A5054219189- dental development and anomalies
- Oral Health Pathology and Treatment
- Cancer-related molecular mechanisms research
- Craniofacial Disorders and Treatments
- Head and Neck Cancer Studies
- Dental Trauma and Treatments
- Connective tissue disorders research
- Facial Nerve Paralysis Treatment and Research
- Oral and Maxillofacial Pathology
- Orthodontics and Dentofacial Orthopedics
- Osteoarthritis Treatment and Mechanisms
- MicroRNA in disease regulation
- Temporomandibular Joint Disorders
- Circular RNAs in diseases
First Affiliated Hospital of Xi'an Jiaotong University
2022-2023
Oral lichen planus (OLP) is a potentially malignant condition with unclear etiology. This study aimed to identify potential biomarkers and mechanisms for OLP progression through bioinformatics analyses.Gene Expression Omnibus (GEO) datasets were screened differentially expressed genes (DEGs) between patients healthy individuals. The functions enriched pathways of the DEGs identified. Sequencing dataset GSE70665 was then used analyze role in development oral squamous cell carcinoma (OSCC)....
Abstract The molecular mechanisms underlying osteogenic differentiation of periodontal ligament stem cells (PDLSCs) under mechanical tension remain unclear. This study aimed to identify a potential long non‐coding ribonucleic acids (lncRNAs)/circular RNAs (circRNAs)‐microRNAs (miRNAs)‐messenger (mRNAs) network in tension‐induced PDLSCs. PDLSCs were isolated from the healthy human ligament, identified, cultured, and exposed tensile force. expression markers was examined, whole transcriptome...
Purpose: The role of periodontal ligament stem cells (PDLSCs) in mediating osteogenesis involved orthodontic tooth movement (OTM) is well established. However, various relevant vitro studies vary the frequency tension. effect tensile on mechanotransduction PDLSCs not clear. current study aimed to determine different frequencies osteogenic differentiation and identify important mechano-sensitivity genes. Methods: Human were isolated, identified, subjected cyclic equibiaxial strain 12% at 0.1...
Periodontal ligament distraction (PDLD) can accelerate orthodontic tooth movement (OTM). However, the effect of stretch frequency on osseous formation during PDLD remains unclear. Here, we sought to identify osteogenic remodelling periodontium.(i) In vitro, five human periodontal stem cell (PDLSC) cultures were randomized either static conditions or exposure a cyclic force involving 12% deformation at frequencies 0.3, 0.5, 0.7 1.0 Hz for 12 h, and differentiation PDLSCs was assessed using...