A5000955309- Advanced Radiotherapy Techniques
- Effects of Radiation Exposure
- Glioma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Childhood Cancer Survivors' Quality of Life
- Advances in Oncology and Radiotherapy
- COVID-19 and healthcare impacts
- Ultrasound and Hyperthermia Applications
- Cancer survivorship and care
- Neuroblastoma Research and Treatments
- Radiation Dose and Imaging
- Head and Neck Cancer Studies
- Sarcoma Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Long-Term Effects of COVID-19
- Lung Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Inflammatory Biomarkers in Disease Prognosis
- Breast Cancer Treatment Studies
- Brain Metastases and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Global Health and Surgery
- Ethics in medical practice
- Patient-Provider Communication in Healthcare
- Cancer therapeutics and mechanisms
Applied Design Labs (United States)
2023
Dignity Health
2023
Emory University
2019-2022
Massachusetts General Hospital
2017-2021
Harvard University
2016-2021
Winship Cancer Institute
2019
Emory and Henry College
2019
Boston University
2019
UC Davis Comprehensive Cancer Center
2012-2018
University of California, Davis
2012-2018
Background Individuals of advanced age with comorbidities face a higher risk death from coronavirus disease 2019 (COVID‐19), especially once they are ventilator‐dependent. Respiratory decline in patients COVID‐19 is precipitated by lung‐mediated aberrant immune cytokine storm. Low‐dose lung radiation was used to treat pneumonia the pre‐antibiotic era. Radiation immunomodulatory effects may improve outcomes for select COVID‐19. Methods A single‐institution trial evaluating safety and efficacy...
Phase 1 clinical trials have established low-dose, whole-lung radiation therapy (LD-RT) as safe for patients with coronavirus disease 2019 (COVID-19)-related pneumonia. By focally dampening cytokine hyperactivation, LD-RT may improve outcomes through immunomodulation.
Background/Objectives: The Pediatric Proton Consortium Registry (PPCR) was established to expedite proton outcomes research in the pediatric population requiring radiotherapy. Here we introduce PPCR as a resource oncology community and provide an overview of data available for further study collaboration. Design/Methods: A multi-institutional registry integrated clinical, dosimetric, radiographic, patient-reported patients undergoing radiation therapy conceived May 2010. Massachusetts...
BACKGROUND Radiotherapy (RT) in the pediatric brain tumor population causes late neurocognitive effects. In current study, authors investigated associations between clinical and dosimetric risk factors memory outcomes a cohort of patients treated with proton radiotherapy (PRT). METHODS A total 70 (median age at PRT, 12.1 years [range, 5.0‐22.5 years]) who were PRT identified baseline follow‐up evaluations visual verbal (Children's Memory Scale third edition Wechsler Scale). Whole‐brain as...
<h3>Importance</h3> Survival of patients with head and neck cancer can be affected by competing causes mortality, as well comorbidities that result in radiation treatment interruptions. <h3>Objective</h3> To discern how differences preexisting medical psychosocial potentially influence adherence to therapy according human papillomavirus (HPV) status. <h3>Design, Setting, Participants</h3> Retrospective analysis at a comprehensive center 162 consecutive locally advanced squamous cell...
Abstract Pediatric radiotherapy is a critical part of pediatric oncology protocols and the quality may determine future life for long‐term survivors. Multidisciplinary team decision making provides basis high‐quality care. However, delivery dependent on resources. This article guidelines good radiation therapy in resource‐limited countries based rational procurement maintenance planning, protocol development, three‐dimensional assurance, adequate staff numbers training.
Abstract Purpose The aim of this work was to comprehensively evaluate a new large field ion chamber transmission detector, Integral Quality Monitor (IQM), for online external photon beam verification and quality assurance. device is designed be mounted on the linac accessory tray measure verify energy, shape, gantry position, fluence before during patient treatment. Methods Our institution evaluated newly developed chamber's effect fluence, response dose, detection modification, accuracy...
Abstract This report by the Radiation Oncology Discipline of Children's Group (COG) describes practice patterns pediatric image‐guided radiotherapy (IGRT) based on a member survey and provides recommendations accordingly. The comprised 11 vignettes asking clinicians about their recommended treatment modalities, IGRT preferences, frequency in‐room verification. Technical questions asked physicists imaging protocols, dose reduction, setup correction, adaptive therapy. In this report, COG an...
BACKGROUND To the authors' knowledge, health‐related quality of life (HRQOL) outcomes are not well described in patients with medulloblastoma. The use proton radiotherapy (RT) may translate into an improved HRQOL. In current study, authors report long‐term HRQOL proton‐treated pediatric METHODS study was a prospective cohort medulloblastoma who were treated RT and enrolled between August 5, 2002, October 8, 2015. Both child parent‐proxy Pediatric Quality Life Inventory (PedsQL) surveys...
It is an exciting time for big data efforts in radiation oncology. The use of to help aid both outcomes and decision‐making research becoming a reality. However, there are true challenges that exist the space gathering utilizing performance data. Here, we summarize current state oncology with respect discuss some
Abstract Background Individuals with advanced age and comorbidities face higher risk of death from COVID-19, especially once ventilator-dependent. Respiratory decline in COVID-19 is mediated by a pneumonic aberrant immune cytokine storm. Low-dose radiation was used to treat pneumonia the pre-antibiotic era. Radiation immunomodulatory effects may improve outcomes COVID-19. Methods We performed single-institution phase I/II trial evaluating safety efficacy single-fraction, low-dose, whole-lung...
Phase I clinical trials have established that low-dose, whole-lung radiotherapy (LD-RT) is safe for patients with COVID-19-related pneumonia. By focally dampening cytokine hyperactivation, LD-RT may improve COVID-19 outcomes through immunomodulation. Patients pneumonia were treated 1.5 Gy LD-RT, followed 28 days, and compared to age- comorbidity-matched controls. Eligible hospitalized, SARS-CoV-2 positive, had radiographic consolidations, required supplemental oxygen. Efficacy endpoints time...
Thirty-seven percent of radiation oncology patients reported distress at least once during treatment. Screening every-other-week intervals optimized efficiency and frequency, identifying nearly 90 distressed with 12 screening events.