There is active debate regarding whether diagnosable depression exists on a continuum with subthreshold depressive symptoms or represents categorically distinct phenomenon. To address this question, multiple indexes of dysfunction (psychosocial difficulties, mental health treatment history, and future incidence major substance abuse/dependence) were examined as function the extent in 3 large community samples (adolescent, adult, older adult; N = 3,003). Increasing levels associated...

Despite the brain's central role in sexual function, little is known about relationships between brain activation and response. In this study, we employed functional MRI (fMRI) to examine arousal a group of young, healthy, heterosexual males. Each subject was exposed two sequences video material consisting explicitly erotic (E), relaxing (R) sports (S) segments an unpredictable order. Data on penile turgidity collected using custom-built pneumatic pressure cuff. Both traditional block...

Objectives We examined the reliability, validity, and factor structure of posttraumatic stress diorder (PTSD) Checklist‐Civilian Version (PCL‐C; Blanchard, Jones‐Alexander, Buckley, & Forneris, 1996) among unselected undergraduate students. Participants were 471 students at a large university in Eastern United States not preselected based on trauma history or symptom severity. Results The PCL‐C demonstrated good internal consistency retest reliability. Compared with alternative measures...

Previous research has linked anger suppression with depression. This study extended prior by comparing people who had recovered from a major depression (RD) those never been depressed (ND). The RD group significantly exceeded the ND in degree to which they reported holding and being afraid express it. Also, participants were more likely endorse attitudes consistent silencing self theory, believing must hide their feelings preserve relationships. They also have experienced an attack. Both...

Major depression has been linked with endorsement of irrational beliefs in cross-sectional research, consistent the rational emotive behavior therapy (REBT) model. In this study, authors extended prior research by using multiple measures irrationality and comparing never-depressed (ND) controls people who had recovered from major depression. Contrary to REBT model, recovered-depressed (RD) group did not significantly exceed ND before, during, or after exposure simulated stressful situations....

Abstract Recent reviews of cognitive theories depression have noted that individualized assessment strategies might help to resolve mixed findings regarding the stability depressotypic beliefs and attitudes. We describe encouraging results for an measure one such construct, irrational beliefs. Twenty depression‐prone women (recurrent major depressives in full remission) twenty closely matched never‐depressed controls completed leading forced‐choice measures (the Belief Scale; BS)...

Background. The question of whether unipolar clinical depression differs categorically from limited depressive complaints has important implications for the disorder's assessment, treatment and research. This crucial issue proven difficult to resolve, in part because many studies date have relied on self-report measures or clinically homogeneous samples. We therefore applied Meehl's taxometric method a large, heterogeneous sample, examined latent structure episodes using both structured...

Background: Agitation is both a feature of major depression and common side effect antidepressant treatment. Depressive agitation correlates with overall severity illness suicide risk, whereas treatment-emergent may contribute to early discontinuation pharmacotherapy. Thus, merits investigation as treatment target in clinical depression. Methods: In this study, adults were evaluated for change other mood symptoms during adjunctive divalproex sodium. Twelve patients on antidepressants, who...

Adolescence is a vulnerable developmental phase marked by physical, psychological, and social changes that rapidly expose young people to wide range of new stressors. When differentiating between bipolar disorder teenage "acting out," careful history important. Adolescent psychiatric illness characterized fluctuating episodes mood elevation depression frequently neither recognized nor formally diagnosed. Adolescents with often manifest more nonepisodic, chronic course continuous...

Dear Editor,
 Cancer is a foremost death cause in each country and substantial hindrance to improving life expectancy, accounting for more than 10 million fatalities 2020, or around one every six [1]. Oral cancer among the leading causes of cancer-related mortality developing countries. squamous cell carcinoma (OSCC) widespread type malignancy associated with tobacco usage human papilloma virus infection. The majority people are diagnosed at an advanced stage, 5-year survival rate OSCC...

Bipolar disorder in children and adolescents can easily be misdiagnosed, as symptom patterns overlap with other mood disorders attention-deficit/hyperactivity commonly differ from adult presentations. A detailed description of the child's behavioral history previous treatment response is critical to accurate diagnosis. Although studies are limited, a number psychopharmaceuticals have been shown provide therapeutic benefit. Parent/caregiver educational support essential components successful...