- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Human Health and Disease
- Congenital Heart Disease Studies
- Healthcare Systems and Public Health
- Cardiac Structural Anomalies and Repair
- Cardiovascular Syncope and Autonomic Disorders
- Pharmacological Effects and Toxicity Studies
- Cardiomyopathy and Myosin Studies
- Functional Brain Connectivity Studies
- Cardiac tumors and thrombi
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Neural dynamics and brain function
- Viral Infections and Immunology Research
- Metabolism and Genetic Disorders
- Pulmonary Hypertension Research and Treatments
- Paraoxonase enzyme and polymorphisms
- Epilepsy research and treatment
- Cardiovascular Issues in Pregnancy
- Obsessive-Compulsive Spectrum Disorders
- Folate and B Vitamins Research
Tomsk National Research Medical Center
2017-2024
Russian Academy of Sciences
2008-2024
Institute of the Human Brain
2008-2023
Siberian State Medical University
2019-2020
Pirogov Russian National Research Medical University
2016-2017
Institute of Cardiology
2016
Ministry of Health of the Russian Federation
2016
Academy of Medical Sciences
2010
Heart rhythm disorders (HRDs) are one of the most complex and urgent problems in both adult pediatric cardiology. One important points research field arrhythmology is study mechanisms HRD formation. The that trigger arrhythmias children have their own peculiarity associated with age-related aspects formation cardiovascular system systems responsible for its regulation, primarily autonomic nervous (ANS). article presents current literature data on contribution ANS to information content...
We evaluated EEG frequency abnormalities in resting state (eyes closed and eyes open) a group of chronic schizophrenia patients as compared with healthy subjects. The study included 3 methods analysis deviation characteristics: genuine EEG, current source density (CSD), independent component (gIC). All have shown that the is characterized by enhanced low-frequency (delta theta) high-frequency (beta) activity comparison control group. However, spatial pattern differences was dependent on type...
Aim . To present the experience and assess complications of permanent pacing in children with bradyarrhythmias based on long-term follow-up. Methods Data 145 structurally normal heart implanted pacemakers at age from 1 month to 18 years were retrospectively assessed. The follow-up was 1999 2020 years. Epicardial pacemaker 71 children, endocardial - 74. mean primary implantation 8.67±5.2 Results following disclosed: hemodynamic (heart chamber enlargement dynamics and/or development...
Abstract Background Radiofrequency ablation (RFA) is the standard method of treatment for tachyarrhythmias in school children, and it leads to complete recovery children without structural heart disease. However, RFA young limited by risk complications unstudied remote effects radiofrequency lesions. Objective To present experience arrhythmias results follow‐up younger children. Materials Methods procedures ( n = 255) were performed 209 with from 0 7 years old. The presented atrioventricular...
Abstract Symptoms in patients with obsessive–compulsive disorder (OCD) are associated impairment cognitive control, attention, and action inhibition. We investigated OCD group differences relative to healthy subjects terms of event‐related alpha beta range synchronization (ERS) desynchronization (ERD) during a visually cued Go/NoGo task. Subjects were 62 296 controls (HC). The comparison HC, showed changed value alpha/beta oscillatory power over the central cortex, particular, an increase...
Aim. To optimize treatment tactics in children with arrhythmias based on the evaluation and prediction of therapy efficacy. Material methods. Prospective cohort study was performed from 2007 to 2017 A total 100 patients aged 0 7 years different types significant received prophylactic antiarrhythmic therapy. Data medical history, 12-lead electrocardiography (ECG), Holter ECG monitoring, echocardiography were studied. verify electrophysiological variant tachycardia, some underwent...
Aim: To evaluate the electrical activity of myocardium and radiofrequency (RF) application zone resulting from ablation (RFA) performed at an early age. Material Methods. A prospective follow-up study included three patients who underwent intracardiac electrophysiological (EPS) effective RFA tachycardia for first time reintervention was required in one case 12 years after procedure two cases six it due to recurrent new-onset arrhythmias. During reintervention, electroanatomical mapping...
Highlights For children aged 11–15 years with the duration of ventricular arrhythmias from 1 to 2 years, increased value β-adrenergic reactivity erythrocyte membranes (β-ARM) is characteristic in comparison group healthy same age, which indicates desensitization β-adrenoreceptors. In early postoperative period after elimination ectopic focus as a result radiofrequency ablation β-ARM continues increase. The possibility using index assess state sympathetic part autonomic nervous system...
Cardiac strangulation is a rare but potentially life-threatening mechanical complication associated with epicardial pacemaker implantation in growing children. This article presents 2 case reports of left ventricular 4- and 3-year-old children who had an system implanted at early age. (Level Difficulty: Advanced.).
to study laboratory parameters of endothelial dysfunction (ED) and their correlation with risk factors (RF) cardiovascular diseases at early stages essential arterial hypertension (AH) in adolescents.We examined 299 adolescents aged 12-18 years EAH. According results 24-hour blood pressure (BP) monitoring all patients were divided into three groups: (1) 98 "white coat hypertension", (2) 108 liable AH (LAH), (3) 93 stable (stAH). Control group consisted 27 healthy adolescents. Examination...
This review discusses the role of autoimmune mechanisms in development heart rhythm disturbances and conduction disorders various origins. The search was performed using PubMed, Medline Google Scholar. Specific cardiovascular diseases (dilated cardiomyopathy, myocarditis, disorders) developing childhood adolescence are associated with an increase titer to intracellular proteins specific myocardiocytes cells cardiac system. Candidate autoantibodies markers for response have been selected....
Primary cardiomyopathies in childhood are a rare but serious disease that is common cause of heart failure and the most reason for transplantation children over one year age. Over past decades, diagnosis cardiomyopathy has advanced from traditional clinical imaging methods to new genetic techniques. The article presents review literature data on modern classification primary pediatric features course imaging, which an integral part based morphofunctional phenotype.
Incidence of cardiovascular diseases (CVD) in children is currently increasing and arterial hypertension ranking number one among them. Changes blood vessels can be detected the developing at preclinical stage. Detection these changes enables to prevent further progression increased pressure via package preventive measures.
Aim: To study structural brain changes according to magnetic resonance imaging (MRI) data in adolescents with essential arterial hypertension (AH). A total of 150 12-18-year-old AH were examined. The average age was 14.9±2.0 years. According 24-hour blood pressure monitoring, patients assigned the following groups: group 1 comprised 44 “white coat hypertension”; 2 50 labile hypertension; 3 6 stable AH. MRI performed at MR-imaging unit “Magnetom-OPEN” practical standard. left ventricle...