A5019717582- Cell Image Analysis Techniques
- AI in cancer detection
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Proteoglycans and glycosaminoglycans research
- Salivary Gland Tumors Diagnosis and Treatment
- Caveolin-1 and cellular processes
- Ubiquitin and proteasome pathways
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Nutritional Studies and Diet
- Radiomics and Machine Learning in Medical Imaging
- Oral Health Pathology and Treatment
- Cancer-related Molecular Pathways
- Gastric Cancer Management and Outcomes
Shaukat Khanum Memorial Cancer Hospital and Research Center
2019-2024
Objective The mitotic activity index is an important prognostic factor in the diagnosis of cancer. task mitosis detection difficult as nuclei are microscopic size and partially labeled, there many more non-mitotic compared to ones. In this paper, we highlight challenges current pipelines propose a method tackle these challenges. Methods Our proposed methodology inspired from recent research on deep learning extensive analysis dataset training pipeline. We first used MiDoG′22 for training,...
The aim of this pilot study was to identify proteins associated with advancement colon cancer (CC).A quantitative proteomics approach used determine the global changes in proteome primary from patients non-cancer normal (NC), non-adenomatous polyp (NAP), non-metastatic tumor (CC NM) and metastatic M) tissues, up- down-regulated proteins. Total protein extracted each biopsy, trypsin-digested, iTRAQ-labeled resulting peptides separated using strong cation exchange (SCX) reverse-phase (RP)...
The aim of the study is to identify cornulin (CRNN) protein expression associated with advancement tongue squamous cell carcinoma (TSCC). A comparison addictive (containing potential carcinogens) versus non-addiction causative agents was expected allow detection differences in CRNN TSCC. Bespoke tissue microarrays (TMAs) were prepared and immunohistochemistry (IHC) performed determine changes epithelial cells node-negative (pN-), node-positive (pN+) TSCC non-cancer patients' oral tissues....
Introduction: Asian developing countries share the burden of colorectal cancer (CRC) with rising mortality rates. This prospective study aims to apprehend clinical relevance age, gender, lifestyle choices (dietary habits and addiction), body mass index (BMI) occurrence progression colon (CC). Methods: A cohort non-cancer CC patients South-Central origin registered for screening colonoscopy or surgery at Shaukat Khanum Memorial Cancer Hospital Research Centre (SKMCH&RC), Lahore, Pakistan,...
Abstract Oral squamous cell carcinoma (OSCC) is the most prevalent subtype of head and neck cancers that has a disproportionately high incidence mortality in developing countries South-Central Asia, including Pakistan. The standard treatment for OSCC generally consists surgery combined with radiotherapy or chemotherapy; however, overall survival rates have not improved, only ~50% patients survive disease. Therefore, identifying validating new drug targets can provide therapeutic options...