A5019769736- Bone Tissue Engineering Materials
- Endodontics and Root Canal Treatments
- Dental Implant Techniques and Outcomes
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Periodontal Regeneration and Treatments
- Photodynamic Therapy Research Studies
- Advanced Drug Delivery Systems
- Laser Applications in Dentistry and Medicine
- Mesenchymal stem cell research
- Oral health in cancer treatment
- Salivary Gland Disorders and Functions
- Steroid Chemistry and Biochemistry
- Oral Health Pathology and Treatment
- Nanoplatforms for cancer theranostics
- Inflammatory mediators and NSAID effects
- Pigment Synthesis and Properties
- Nicotinic Acetylcholine Receptors Study
- Air Quality and Health Impacts
- TGF-β signaling in diseases
- Cancer-related gene regulation
- Dental Radiography and Imaging
- Electrospun Nanofibers in Biomedical Applications
- Occupational exposure and asthma
- Phytochemistry and Biological Activities
Shahid Beheshti University of Medical Sciences
2016-2025
Shahid Beheshti University
2021-2023
Tehran University of Medical Sciences
2011-2013
University of Tehran
2007-2011
Biotechnology Research Center
2011
In the pharmaceutical industry, hard- and soft-shelled capsules are typically made from gelatin, commonly derived bovine porcine sources. To ensure that products comply with halal regulations in Muslim countries (no allowed), development of a valid, reliable, quick, most importantly, cost-effective tests utmost importance.We developed species-specific duplex polymerase chain reaction (PCR) assay targeting 149 bp 271 mitochondrial DNA (mtDNA) to simultaneously detect both (in one at same...
Different degrees of clinical success have been reported for synthetic, allograft, and xenograft bone substitutes in human trials. Although these clinically investigated, their vitro effects on cell differentiation remain unclear. Proliferation, differentiation, attachment dental pulp stem cells (DPSCs) to β-tricalcium phosphate (β-TCP), freeze-dried allograft (FDBA), deproteinized bovine mineral (DBBM) were compared this study. MTT assay, measurement total DNA, reverse transcriptase...
Abstract Pirfenidone (PFD), one acceptable medication for treating idiopathic pulmonary fibrosis (IPF), is not well tolerated by patients at full doses. Hence, employing of some approaches such as combination therapy may be applicable increasing therapeutic efficacy PFD. Losartan (LOS), an angiotensin II receptor antagonist, could a suitable candidate because its stabilizing effect on the function IPF patients. Therefore, this study aimed to investigate effects LOS in with PFD bleomycin...
This study aimed to assess the cytotoxicity and proliferation effects of cold ceramic (CC) on stem cells from human exfoliated deciduous teeth(SHEDs) compared mineral trioxide aggregate(MTA). In this in vitro study, fresh set MTA CC for SHEDs was assessed after 24 72 h using methyl thiazolyl tetrazolium(MTT) assay. The scratch test used evaluate cell migration, while morphology adhesion were by scanning electron microscopy (SEM). Data analyzed one-way ANOVA Tukey (alpha = 0.05). At h,...
This study compared the antioxidant, cytotoxic, and antibacterial effects of Citrus reticulata (C. reticulata) peel Olea europaea (O. europaea) leaf hydroalcoholic extracts essential oils. In this in vitro study, effect C. O. oils was evaluated on Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) by agar diffusion test. Their minimum inhibitory concentration (MIC) bactericidal (MBC) were determined broth microdilution method. cytotoxicity against human gingival fibroblasts...
This in vitro study assessed the effects of bonding application time (immediate vs. 24-hour delay) and strategy [self-etch (SE) etch-and-rinse (ER)] on cytotoxicity three calcium silicate-based cements [calcium-enriched mixture (CEM) cement, ProRoot mineral trioxide aggregate (MTA) Biodentine] at 1mm 2mm thicknesses. Specimens (n=20 per group) were fabricated using CEM, MTA, Biodentine. Scotchbond Universal was applied immediately or after 24 hours via SE ER strategies. Cytotoxicity cement...
Background . Focusing on novel drug combinations that target different pathways especially apoptosis and MAPK could be a rationale for combination therapy in successful treatment of lung cancer. Concurrent use cyclooxygenase (COX) inhibitors with arsenic trioxide (ATO) might possible option. Methods Cytotoxicity ATO, dexamethasone (Dex), celecoxib (Cel), Indomethacin (Indo) individually or was determined at 24, 48, 72 hrs A549 cancer cells. The COX-2 gene protein expression, pathway...
This study assessed the effect of low-level laser irradiation (LLLI) on proliferation and osteogenic differentiation dental pulp stem cells (DPSCs). DPSCs were exposed to 810 nm light (0.1, 0.2, or 0.3 J cm−2) for 7 d (60 s daily). The negative control group (cells in regular medium) positive medium (OM)) not lased. One OM was irradiated with operated at 0.2 cm−2. Cell viability evaluated 24 h one week after last day using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)...
The objective of the present study is to report effects beta-increase and alpha- increase EEG feedback training along with alpha-theta biofeedback in two patients diagnosed anxiety disorder. Symptom Checklist-90-Revised (SCL-90-R) patients' self reports were used as measures treatment efficacy. Following 30 sessions within a three-month period, reported significant reduction anxiety-related symptoms. At one-year follow-up, results SCL-90-R showed all clinical scales normal range. In...
Nicotine has adverse cellular and molecular effects on oral mucosa, bone, teeth. Vitamin E (α-tocopherol) vitamin C (ascorbic acid) are biological antioxidants with positive wound healing bone formation. This in vitro study sought to assess the cytotoxic of different concentrations nicotine cotinine (a metabolite nicotine) MG-63 osteoblast-like cells human gingival fibroblasts (HGFs) presence absence antioxidant vitamins (separately combined). Cell viability proliferation were assessed using...
Different compounds of smoking (e.g., nicotine and cotinine) are risk factors for various diseases such as oral cancer periodontal diseases. Some studies reported the negative effects on cell proliferation differentiation. The present in vitro study assessed cotinine (long-acting metabolite nicotine) attachment viability human gingival fibroblast (HGF) cells to tooth root surfaces.A total 70 teeth specimens were placed into 48-well culture plates covered with HGF suspension, complete...
In the present study, we aimed to fabricate poly-lactic-co-glycolic acid (PLGA) microspheres containing a mixture of three antibiotics-minocycline, metronidazole, and ciprofloxacin (MMC)-to assess their efficacy properties.MMC were loaded onto PLGA biopolymer at 1:1:1 ratio using double emulsion technique. The morphology was observed by (SEM). controlled release antibiotics evaluated over an 18-day period. antibacterial released against Aggregatibacter actinomycetemcomitans measuring...
The purpose of the present study was to compare cytotoxicity Reso-Pac and Coe-Pak periodontal dressing.According ISO-10993-12:2012, 1-, 3- 7-day extracts two dressings were prepared in cell culture medium exposed cultured lines. Cell viability proliferation at 24 h 72 following exposure evaluated using quantitative MTT assay.The results showed a significant (P < 0.05) reduction cells compared control group (no extract). slightly decreased group. Understudy materials greater against human...