Martina Moreno-Fina

ORCID: 0000-0003-4828-8667
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About
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Research Areas
  • 3D Printing in Biomedical Research
  • Pluripotent Stem Cells Research
  • Neuroscience and Neural Engineering

Universitat de Barcelona
2022

Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the brain. Here we investigated whether neuronal derived induced pluripotent stem cells (hiPSCs) feature key advantages compared with rodent cultures. Using calcium fluorescence imaging, tracked spontaneous activity in hiPSC-derived, human, rat their dynamic functional behavior as they matured. We observed that hiPSC-derived...

10.1016/j.stemcr.2022.11.014 article EN cc-by-nc-nd Stem Cell Reports 2022-12-22
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