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Research Areas
- 3D Printing in Biomedical Research
- Pluripotent Stem Cells Research
- Neuroscience and Neural Engineering
Universitat de Barcelona
2022
Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the brain. Here we investigated whether neuronal derived induced pluripotent stem cells (hiPSCs) feature key advantages compared with rodent cultures. Using calcium fluorescence imaging, tracked spontaneous activity in hiPSC-derived, human, rat their dynamic functional behavior as they matured. We observed that hiPSC-derived...
10.1016/j.stemcr.2022.11.014
article
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cc-by-nc-nd
Stem Cell Reports
2022-12-22
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