A5080257830- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Anesthesia and Pain Management
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Adenosine and Purinergic Signaling
- Cardiac Ischemia and Reperfusion
- Cardiac Arrest and Resuscitation
- Nitric Oxide and Endothelin Effects
- Hip and Femur Fractures
- Blood transfusion and management
- Diversity and Career in Medicine
- Acute Kidney Injury Research
- Liver Disease Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Family and Patient Care in Intensive Care Units
- Surgical Simulation and Training
- Maternal and Perinatal Health Interventions
Tel Aviv University
2016-2025
Tel Aviv Sourasky Medical Center
2014-2024
RWTH Aachen University
2017
University of Pennsylvania
1993-2017
University of Wisconsin–Madison
2017
Hadassah Medical Center
2000-2015
Pain and Rehabilitation Medicine
2015
Shaare Zedek Medical Center
2014
University Medical Center
1998-2014
Stanford Medicine
2014
The debate over the correct perioperative fluid management is unresolved.The impact of two intraoperative regimes on postoperative outcome was prospectively evaluated in 152 patients with an American Society Anesthesiologists physical status I-III who were undergoing elective intraabdominal surgery. Patients randomly assigned to receive intraoperatively either liberal (liberal protocol group [LPG], n = 75; bolus 10 ml/kg followed by 12 ml x kg(-1) h(-1)) or restrictive (restrictive [RPG],...
Awake craniotomy for removal of intraaxial tumors within or adjacent to eloquent brain regions is a well-established procedure. However, awake failures have not been well characterized. In the present study, authors aimed analyze and assess incidence causes failed craniotomy.The database craniotomies performed at Tel Aviv Medical Center between 2003 2010 was reviewed. considered failure if conversion general anesthesia required, adequate mapping monitoring could achieved.Of 488 patients...
Awake craniotomy (AC) for removal of intra-axial brain tumors is a well-established procedure. However, the occurrence and consequences intraoperative seizures during AC have not been well characterized.To analyze incidence, risk factors, AC.The database at Tel Aviv Medical Center between 2003 to 2011 was reviewed. Occurrences were analyzed with respect medical history, medications, tumor characteristics, postoperative outcome.Of 549 ACs performed index period, 477 complete records...
Background Intraoperative hypotension might contribute to the development of postoperative delirium through inadequate cerebral perfusion. However, evidence regarding association between intraoperative and is equivocal. Therefore, hypothesis that associated with in patients older than 70 yr having elective noncardiac surgery was tested . Methods This a retrospective cohort analysis who underwent single tertiary academic center 2020 2021. quantified as area under mean arterial pressure (MAP)...
Background Perioperative myocardial ischemia occurs in 35% of unselected elderly patients undergoing hip fracture surgery. epidural analgesia may reduce the incidence adverse cardiac events. Methods The effect early administration during stressful period, on events was evaluated a prospective randomized study 68 with fractures who either had known coronary artery disease or were at high risk for disease. On admission to emergency room, assigned receive usual care analgesic regimen...
Background Liver resection is a major operation for which, even with the improvements in surgical and anesthetic techniques, reported rate of blood transfusion was rarely less than 30%. About 60% transfused patients require only 1 or 2 units blood, requirement that may be accommodated by use acute normovolemic hemodilution (ANH). Methods The efficacy, hemodynamic effects, safety ANH were investigated randomized, active-control study American Society Anesthesiologists status I-II who...
Safe and effective alternatives are required in labor when epidural analgesia is not appropriate. We hypothesized that patient-controlled IV remifentanil would be inferior to analgesia.This randomized nonblinded controlled noninferiority study healthy women with a singleton fetus vertex presentation was performed at 1 site. Women were receive titrated from 20 mcg up maximum bolus dose of 60 lockout interval 2 minutes, or 0.1% bupivacaine mcg/mL fentanyl (initiation 15 mL; maintenance 10 mL,...
To determine whether intraoperative fluid management affects urine output in patients undergoing laparoscopic bariatric operations.Randomized controlled trial.Academic tertiary referral center.Morbidly obese scheduled to undergo procedures.Patients were randomly assigned receive intraoperatively high (10 mL/kg/h, n = 55) or low (4 52) amounts of Ringer lactate solution.The primary end point was output. Secondary points postoperative creatinine serum concentration and complication...
Significance We studied how anesthesia-induced loss of consciousness (LOC) affects processing external sensory events at single-neuron resolution in epilepsy patients implanted with depth electrodes for clinical treatment. Just before electrode removal, were lightly anesthetized propofol while we presented sounds around LOC. found that auditory responses widespread across the brain during wakefulness. Upon LOC, robust persisted primary cortex high-order regions mostly attenuated. In...
The surgical strategy for the treatment of resectable synchronous hepatic metastases colorectal cancer remains controversial. This study was performed to assess outcome combined resection and liver metastases.The perioperative data, morbidity, survival patients who underwent colon resections from 1988 1999 were compared parameters followed by in a staged setting.198 performed, which 112 procedures 103 done metastatic carcinoma. Twenty six (25%) had 86 with metachronous staging setting....
BackgroundTransfusion of allogeneic blood influences outcome after surgery. Despite widespread availability transfusion guidelines, practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount packed red cells (pRBC) products transfused intraoperatively, describe factors determining throughout Europe.MethodsWe did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit...
To test the hypothesis that in surgical patients ≥70 years, preoperative cognitive impairment is independently associated with postoperative delirium.Postoperative delirium common among elderly and longer hospitalization significant morbidity. Some evidence suggest baseline an important risk factor. Routine screening for both recommended older patients. As of 2019, we implemented such routine perioperative all elective years.Retrospective single-center analysis prospectively collected data...
Integrating artificial intelligence (AI) into intensive care practices can enhance patient by providing real-time predictions and aiding clinical decisions. However, biases in AI models undermine diversity, equity, inclusion (DEI) efforts, particularly visual representations of healthcare professionals. This work aims to examine the demographic representation two text-to-image models, Midjourney ChatGPT DALL-E 2, assess their accuracy depicting characteristics intensivists.
Many drugs are removed by the lung. The pulmonary uptake of one drug can be inhibited when a second, highly accumulated is administered parenterally or as chronic oral treatment. effect inhalational anesthetics on has not been extensively studied and may alter pharmacokinetics intravenously drugs.The propofol lung during single passage through circulation was in four groups anesthetized cats: spontaneously breathing cats (control group, n = 6), whose lungs were mechanically ventilated (n...