Yan Sun

ORCID: 0000-0003-4838-0877
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Research Areas
  • Cancer Immunotherapy and Biomarkers
  • Fatty Acid Research and Health
  • Eicosanoids and Hypertension Pharmacology
  • Natural Products and Biological Research
  • Iron Metabolism and Disorders
  • HIV, Drug Use, Sexual Risk
  • Schizophrenia research and treatment
  • Peptidase Inhibition and Analysis
  • Hemoglobinopathies and Related Disorders
  • Renal cell carcinoma treatment
  • CAR-T cell therapy research
  • Metabolism and Genetic Disorders
  • Inflammatory Biomarkers in Disease Prognosis
  • Hypertrophic osteoarthropathy and related conditions
  • Organ Transplantation Techniques and Outcomes
  • Extracellular vesicles in disease
  • Genomics and Rare Diseases
  • Colorectal and Anal Carcinomas
  • Advanced Neuroimaging Techniques and Applications
  • HIV/AIDS Research and Interventions
  • Parathyroid Disorders and Treatments
  • Mast cells and histamine
  • Aortic Thrombus and Embolism
  • Pancreatic and Hepatic Oncology Research
  • Ion channel regulation and function

Peking University
2024

Peking University Cancer Hospital
2024

BGI Genomics
2023

BGI Group (China)
2023

Dalian Municipal Central Hospital
2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2021

Capital Medical University
2021

Dalian Medical University
2014-2016

Kinjo Gakuin University
2006

Research Articles| January 26 2009 Démonstrations cliniques d'une série d'affections de l'oesophage Subject Area: Gastroenterology M. Michaud Lausanne Search for other works by this author on: This Site PubMed Google Scholar Gastroenterologia (1939) 64 (5-6): 263–267. https://doi.org/10.1159/000197809 Content Tools Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter LinkedIn Email Get Permissions Cite Citation Michaud; l'oesophage....

10.1159/000097809 article EN KARGER eBooks 2006-01-01

Abstract Penpulimab is an anti-programmed cell death-1 (PD-1) IgG1 antibody with no Fc gamma receptor (FcγR) binding activity, and thus theoretically reduced immune-related adverse events (irAEs) while maintaining efficacy. This single-arm, phase II trial conducted across 20 tertiary care centers in China enrolled adult patients metastatic nasopharyngeal carcinoma (NPC) who had failed two or more lines of previous systemic chemotherapy. Patients received 200-mg penpulimab intravenously every...

10.1038/s41392-024-01865-6 article EN cc-by Signal Transduction and Targeted Therapy 2024-06-18

With the rapidly evolving of immune checkpoint inhibitors (ICIs), it has shown remarkable clinical benefits in treating various cancers. However, immune-related adverse events (irAEs) remain a significant challenge management patients undergoing immunotherapy. There are limited data about immunotherapy re-challenge with renal clear cell cancer who had irAE initial ICI therapy. In this study, we reported case patient advanced developed serious irAEs but also achieved partial remission tumor...

10.3389/fimmu.2023.1270828 article EN cc-by Frontiers in Immunology 2023-10-17

Objectives As one of the most common hereditary diseases, thalassemia affects a large number people in China. The aim this study was to investigate feasibility method based on next-generation sequencing (NGS) for screening carriers among high school students Shaoguan area. Materials and Methods NGS-based performed using 25,910 recruited from 38 schools. yield systematically analyzed. Before screening, lecture how disease is inherited, symptoms thalassemia, prevent it given 28,780 students....

10.1177/09691413231188069 article EN Journal of Medical Screening 2023-07-12

Abstract The abnormality of large-conductance calcium-activated potassium channels (BK channels) is an important factor in inducing vascular inflammation. BK channel agonists can readily recover function and improve However, it not clear how to dysfunction caused by downregulation protein expression. This study found that angiotensin II-1 receptor autoantibodies (AT1-AA), which are widely present the body various types cardiovascular diseases, down-regulate expression induce Further research...

10.1101/2021.10.17.464722 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-10-17
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