Olga V. Chumakova

ORCID: 0000-0003-4839-7628
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About
Contact & Profiles
Research Areas
  • Human Health and Disease
  • Healthcare Systems and Public Health
  • Neuroscience and Neuropharmacology Research
  • Ultrasound and Hyperthermia Applications
  • Legal and Policy Issues
  • Agricultural Development and Policies
  • Child and Adolescent Health
  • Legal and Regulatory Analysis
  • Economic and Technological Systems Analysis
  • Photoacoustic and Ultrasonic Imaging
  • Digital Transformation in Law
  • Regional Economic Development and Innovation
  • Nanoplatforms for cancer theranostics
  • Photoreceptor and optogenetics research
  • Thyroid Disorders and Treatments
  • Industrial Engineering and Technologies
  • Retinoids in leukemia and cellular processes
  • Food Industry and Aquatic Biology
  • Eicosanoids and Hypertension Pharmacology
  • Molecular Sensors and Ion Detection
  • Aerospace, Electronics, Mathematical Modeling
  • Construction Management and Sustainability
  • Photosynthetic Processes and Mechanisms
  • HIV, TB, and STIs Epidemiology
  • Infectious Encephalopathies and Encephalitis

Maternity and Children's Hospital
2024

The University of Texas Health Science Center at Houston
2012-2023

Moscow State University of Civil Engineering
2017-2019

Samara State Agrarian University
2019

The University of Texas Medical Branch at Galveston
2006-2011

Academy of Medical Sciences
2007

Scientific Center of Children's Health
2007

University of Missouri–Kansas City
2002

National Academy of Sciences of Belarus
1996-2000

Type 1 diabetes mellitus (T1DM) is the most common form of in childhood, where, unlike adults, it accounts for more than 90% all cases diabetes. The constant change epidemiology T1DM with significant differences populations and regions requires systematic data collection analysis timely monitoring trends.

10.14341/probl13515 article EN cc-by-nc-sa Problems of Endocrinology 2024-11-04

All-trans-retinoic acid is a metabolite of vitamin A (all-trans-retinol) that functions as an activating ligand for family nuclear retinoic receptors. The intracellular levels in tissues are tightly regulated, although the mechanisms underlying control retinoid metabolism at level specific enzymes not completely understood. In this report we present first characterization substrate specificity novel short-chain dehydrogenase/reductase (SDR) encoded by RalR1/PSDR1, cDNA recently isolated from...

10.1074/jbc.m202588200 article EN cc-by Journal of Biological Chemistry 2002-08-01

All-trans-retinol is the precursor for all-trans-retinoic acid, activating ligand nuclear transcription factors retinoic acid receptors. In cytosol of various cells, most retinol exists in a bound form, complexed with cellular binding protein type I (holo-CRBP). Whether produced from free or form not yet clear. Here, we present evidence that holo-CRBP recognized as substrate by human microsomal short-chain dehydrogenase/reductase (SDR) RoDH-4 K(m) value close to liver concentration...

10.1021/bi026836r article EN Biochemistry 2002-12-31

We developed a methodology for high yield synthesis of gold nanorods (GNR) with narrow band optical absorption centered at 760 nm. GNR were purified from hexadecyltrimethylammonium bromide (CTAB) and coated polyethylene glycol (PEG). The molar ratio between PEG (1÷50000) was optimized to make the conjugate biocompatible PEG-GNR contrast agent optoacoustic (OA) imaging. In vitro toxicity studies showed no significant change in survival rates cultured normal (IEC-6, MDCK) cancer (SKBR3 HEPG2)...

10.1166/nnl.2012.1387 article EN Nanoscience and Nanotechnology Letters 2012-07-01

The aim of the study was improvement and gain in efficiency preventive medical examinations minors. There were studied information statistical materials dispanserization children population Russian Federation 2014 concerning health various age groups terms Federal districts subjects. analyzed indices coverage children’s with routine examination; level structure revealed general primary prevalence; frequency dispensary registration; neediness additional consultations, treatment conditions...

10.18821/1560-9561-2016-19-5-287-293 article EN Russian Pediatric Journal 2019-04-30

Background. Neonatal screening for congenital hypothyroidism (CH) allows the timely diagnosis of disease and onset replacement therapy. Analytical research in field health care provides basis making managerial decisions, particular by public authorities. Objective — study objective was to analyze results neonatal Russian Federation. Material methods. We analyzed reports local authorities (LHAs) on activities regional medical genetic services, which were monthly submitted Ministry Health The...

10.14341/probl8752 article EN cc-by-nc-sa Problems of Endocrinology 2018-04-09

The paper pointed out that the concept of smart city - is basis for development area within clearly defined borders. It was found each components cities should be offered to format uniform and structuring overall paradigm region.

10.1051/matecconf/201710601030 article EN cc-by MATEC Web of Conferences 2017-01-01

We proposed and have been developing real-time, noninvasive monitoring of blood oxygenation, total hemoglobin concentration, thermotherapy including hyperthermia, coagulation, cryotherapy. In this paper we propose to use the optoacoustic technique for nanoparticle-mediated photothermal therapy (NPT) tumors. NPT is based on heating exogenous strongly-absorbing nanoparticles selectively delivered in Real-time necessary precise tumor with minimal damage normal tissues. study injected PEGylated...

10.1117/12.714302 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2007-02-08

Background. Neonatal screening for congenital hypothyroidism (CH) allows the timely diagnosis of disease and onset replacement therapy. Analytical research in field health care provides basis making managerial decisions, particular by public authorities. Objective — study objective was to analyze results neonatal Russian Federation. Material methods. We analyzed reports local authorities (LHAs) on activities regional medical genetic services, which were monthly submitted Ministry Health The...

10.14341/probl201864114-20 article EN cc-by-nc-sa Problems of Endocrinology 2018-04-09

The article notes that the development of recreation and tourism at present stage society is given more attention, because this type activity for many countries regions strategic, in sphere priority territories, including European Union. authors note tourist recreational activities are considered to be one most profitable world. importance identifying components potential territory their interrelations, as well degree influence on effectiveness tourism. novelty work calculation adapted...

10.14505//jemt.v9.8(32).03 article EN Journal of Environmental Management and Tourism 2019-04-11

The article is dedicated to the problem of insufficient regulation legal status road users in Russia using personal mobility devices (e-scooters, segways, etc.) and rules that apply them. paper analyzes scientific views on this problem. author uses analysis applicable Russian laws available international experience matter express a number proposals aimed at ensuring safe integration contemporary technical pedestrian, bicycle automobile space.

10.18572/2071-1166-2024-3-60-64 article EN Administrative law and procedure 2024-02-29

The international aspect of combating circulation counterfeit goods lies in the fact that are often manufactured outside state where they consumed. This means efficient on global level requires cooperation between various countries, and national level, law enforcement authorities, business citizens.

10.18572/1812-3910-2024-3-39-43 article EN Public international and private international law 2024-08-29

Male rats were injected with ethanol as a 25% solution (3.5 g/kg body weight) and then the duration of retention righting reflex (DRR) well ethanol-induced sleep (DEIS) recorded. On basis DEIS in 60 rats. we selected four groups six each: short-sleep group (SS. 34 ± 5 min). intermediate-sleep (IS. 118 ±3 long-sleep (LS. 186 ±5 min) non-sleep (NS. 0 The striatal crude mitochondrial fraction was assayed for acetylcholinesterase activity (AChE, EC 3.1.1.7) high-affinity choline uptake. NS...

10.1093/oxfordjournals.alcalc.a008134 article EN Alcohol and Alcoholism 1996-03-01

The article presents the interim results of realization activities federal project «Development pediatric health care including creation modern infrastructure for medical aid» included in National «Health care». role Roszdravnadzor and main directions its real-time monitoring system over given regions Russian Federation are demonstrated.

10.35576/article_5d651dbc4c9885.75717307 article EN Vestnik Roszdravnadzora 2019-08-22

10.17223/22253513/19/7 article EN Vestnik Tomskogo gosudarstvennogo universiteta Pravo 2016-03-01
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