Alexandre Coutinho Teixeira de Freitas

ORCID: 0000-0003-4864-4940
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Organ Transplantation Techniques and Outcomes
  • Liver Disease and Transplantation
  • Organ Donation and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Bariatric Surgery and Outcomes
  • Nutrition and Health in Aging
  • Gallbladder and Bile Duct Disorders
  • Occupational Health and Safety in Workplaces
  • Diet and metabolism studies
  • Body Contouring and Surgery
  • Pediatric Hepatobiliary Diseases and Treatments
  • Congenital Anomalies and Fetal Surgery
  • Renal Transplantation Outcomes and Treatments
  • Pancreatic and Hepatic Oncology Research
  • Gastroesophageal reflux and treatments
  • Advanced machining processes and optimization
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Hernia repair and management
  • Abdominal vascular conditions and treatments
  • Trauma and Emergency Care Studies
  • T-cell and B-cell Immunology
  • Gastrointestinal disorders and treatments
  • Appendicitis Diagnosis and Management
  • Pelvic and Acetabular Injuries
  • Healthcare Regulation

Universidade Federal do Paraná
2013-2024

Hospital de Clínicas Universidade Federal do Paraná
2001-2023

Hospital Nossa Senhora das Graças
2007-2022

Universidade Federal Rural do Rio de Janeiro
2022

Escola de Comando e Estado-Maior do Exército
2018

Hospital de Clínicas de Porto Alegre
2015

Brazilian Society of Computational and Applied Mathematics
2010

Universidade Federal do Maranhão
2006

Centro Universitário Curitiba
2005

University of Coimbra
2001

ABSTRACT Background: Median arcuate ligament syndrome(MALS) is a rare condition thatmay cause significant clinical manifestations, including abdominal pain and weight loss. Its diagnosis may be difficult very often delayed. The laparoscopic approach became the standard treatment of MALS. Aim: To assess outcome in patients with Method: data sixpatients MALS who were subjected to sectioning median retrospectively reviewed.The following evaluated: age, gender, diagnostic tests findings, ASA...

10.1590/0102-672020190001e1495 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2020-01-01

The polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women at childbearing age. Metabolic present from 28% to 46% patients with PCOS. Non-alcoholic fatty liver disease (NAFLD) considered hepatic expression metabolic syndrome. There are few published studies that correlate PCOS and NAFLD.To determine prevalence NAFLD PCOS, verify if there a correlation between this population.Study developed Gynecology Department Clinical Hospital Federal University Parana...

10.1590/s0004-28032015000200008 article EN cc-by-nc Arquivos de Gastroenterologia 2015-05-30

Os inibidores da bomba de prótons (IBPs) são medicamentos amplamente utilizados para tratar condições gastrointestinais, como refluxo gastroesofágico e úlceras pépticas. Embora sejam bastante eficazes no curto prazo, o uso prolongado desses remédios pode trazer riscos à saúde, fraturas ósseas relacionadas osteoporose, baixos níveis magnésio sangue (hipomagnesemia), maior chance pneumonia adquirida na comunidade problemas renais. Este estudo teve objetivo analisar, forma crítica, as...

10.69849/revistaft/cs10202501250727 article PT Revista fisio&terapia. 2025-01-25

O câncer gastrointestinal (CGI) é uma das principais causas de mortalidade global, sendo o colorretal, gástrico e esofágico os mais prevalentes, com 2 milhões casos anuais. presente estudo teve como objetivo avaliar tecnologias emergentes no diagnóstico precoce manejo terapêutico do CGI, foco em biomarcadores, inteligência artificial (IA) terapias personalizadas. Realizou-se revisão integrativa utilizando bases dados PubMed, SciELO BVS, considerando estudos publicados entre 2024 2025. Foram...

10.56083/rcv5n1-086 article PT cc-by-nc Revista Contemporânea 2025-01-27

Introduction : Malgré des preuves solides démontrant les bienfaits de l’activité physique sur effets secondaires du cancer sein et traitements associés, nombreuses patientes ont tendance à être physiquement inactives. Comprendre quels facilitateurs quelles barrières influencent leur engagement dans la pratique d’activité physique, son maintien, représente une première étape vers conception d’interventions ciblées visant accroître pratique. Le but cette étude est décrire déterminants associés...

10.3917/spub.251.0151 article FR Santé Publique 2025-03-11

A leptospirose é uma doença infecciosa zoonótica causada por bactérias do gênero Leptospira, os roedores se mostram como principais reservatórios, capazes de disseminar meio da urina. transmissão para seres humanos dá-se contato com água e solo contaminado. enfermidade destaque no que refere aos problemas saúde pública, possui alta taxa mortalidade morbidade, em regiões clima tropical condições tanto ambientais quanto socioeconômicas sua disseminação. No Brasil, caráter endêmico maior...

10.54033/cadpedv22n6-066 article PT Caderno Pedagógico 2025-04-07

ABSTRACT Background: Laparoscopic cholecystectomy is the preferable treatment for chronic or acute cholecystitis. Some factors may increase rate of laparoscopic conversion to open and perioperative complications. The role gender as a risk factor controversial. Aim: To evaluate on operative findings outcome cholecystectomy. Method: All patients who underwent cholecystitis were included. Demographic, clinical, laboratory, imaging exams, intraoperative postoperative data obtained analyzed. was...

10.1590/0102-672020190001e1438 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2019-01-01

OBJETIVOS: Determinar a opinião e o conhecimento, de uma amostra da população cidade Curitiba, sobre doação transplante órgãos. MÉTODOS: A conhecimento órgãos mil pessoas, com idade superior 18 anos, foram determinados através um questionário 20 perguntas. Os entrevistados avaliados tinham distribuição similar em idade, sexo padrão socioeconômico, escolaridade à brasileira, determinada pelo IBGE. RESULTADOS: maioria dos (87,8%) era favorável Não houve diferença na percentagem relação sexo,...

10.1590/s0104-42302007000500018 article PT cc-by Revista da Associação Médica Brasileira 2007-10-01

Insulin-like growth factor I (IGF-I) is produced almost entirely by the liver and main promoter of anabolic hormone (GH) effects on protein, carbohydrate, lipid metabolism. IGF-I significantly decreased in patients with cirrhosis. Our objective was to determine relationship between circulating MELD (Model for End-stage Liver Disease) cirrhotics subjected orthotopic transplantation (OLT). We also assessed changes its major binding protein (IGF-binding protein-3 or IGFBP-3) after OLT.In a...

10.12659/aot.883819 article EN Annals of Transplantation 2013-01-01

Context Hypogonadism is a common clinical situation in male patients with liver cirrhosis. Objectives The aim of the present study was to evaluate effects orthotopic transplantation on testosterone, free testosterone and sex hormone-binding globulin advanced disease also determine relationship these changes Model for End-stage Liver Disease (MELD) score. Methods In prospective study, serum levels 30 adult end-stage were measured 2 4 hours before 6 months after transplantation. Results Total...

10.1590/s0004-28032014000100012 article EN cc-by-nc Arquivos de Gastroenterologia 2014-03-01

ABSTRACT Background: Serum sodium was incorporated to MELD score for the allocation of liver transplantation In USA in 2016. Hyponatremia significantly increased efficacy predict mortality on waiting list. Such modification not adopted Brazil. Aim: To carry out a simulation using MELD-Na as list ordering criteria state Paraná and compare ordered according score. Methods: The study used data 122 patients hepatic listed at Parana´s Transplantation Central. Two classificatory lists were set up,...

10.1590/0102-672020190001e1460 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2019-01-01

ABSTRACT BACKGROUND: The incidence of biliary duct injuries remains higher in laparoscopic cholecystectomy (LC) comparison to open surgery. Critical View Safety (CVS) was introduced by Strasberg as a strategy for reducing this catastrophic complication. AIM: aim study evaluate how often an adequate CVS is achieved during LC, the determining factors its success, and associated surgical outcomes. METHODS: This prospective study. photographs all patients who underwent LC same surgeon between...

10.1590/0102-6720202400034e1827 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2024-01-01

INTRODUÇÃO: Muitas substâncias de origem vegetal são utilizadas desde os primórdios da civilização com finalidade melhorar a cicatrização. Dentre elas, foi demonstrado em ratos que o extrato folhas secas Passiflora edulis tem efeito antiinflamatório. OBJETIVO: Investigar do na cicatrização das gastrorrafias ratos. MÉTODOS: Foram utilizados 40 Wistar, machos, adultos, divididos dois grupos 20 denominados grupo Controle e (GP GC) subdivididos 10 acordo momento óbito, no 3º 7º dias...

10.1590/s0102-86502006000800009 article PT cc-by Acta Cirúrgica Brasileira 2006-01-01

<i>Background/Aims: </i>Our objective is to assess donor complications in all right hepatic lobe living-donor liver transplantation (LDLT) at our center. <i>Methods:</i> Of a total of 352 transplantations performed, 60 were right-lobe LDLT. Most donors (88.3%) related the recipients. <i>Results:</i> Mean hospital stay was 5.4 8 0.6 days. No occurred due preoperative evaluation. received one or two units autologous blood transfusion. Only 5 (8.3%) needed...

10.1159/000102898 article EN Digestive Surgery 2007-01-01

CONTEXT: Presently the MELD score is used as waiting list criterion for liver transplantation in Brazil. In this method more critical patients are considered priority to transplantation. OBJECTIVE: To compare results of when chronologic was organ allocation (pre-MELD era) with period (MELD one unit METHODS: The charts subjected at Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, PR, Brazil, were reviewed from January 2001 August 2008. Patients divided into two groups:...

10.1590/s0004-28032010000300004 article EN cc-by-nc Arquivos de Gastroenterologia 2010-09-01

ABSTRACT Background: Biliary reconstitution has been considered the Achilles’s heel of liver transplantations due to its high rate postoperative complications. Aim: To evaluate risk factors for occurrence biliary strictures and leakages, most efficient methods their treatment. Method: Of 310 patients who underwent transplantation between 2001 2015, 182 medical records were retrospectively analyzed. Evaluated included demographic profile, type reconstitution, presence vascular complications,...

10.1590/0102-6720201700020011 article EN cc-by ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2017-06-01

INTRODUÇÃO: A cicatrização é evento biológico complexo envolvendo inflamação, quimiotaxia, proliferação celular, diferenciação e remodelação. Na medicina popular brasileira, utiliza-se a Aroeira para tratar as mais diversas situações patológicas No Estado do Maranhão - Brasil, extensivamente utilizada no tratamento de afecções aparelho respiratório, digestivo ginecológico. As anastomoses intestinais sempre foram motivo preocupação cirurgiões constituem, até hoje assunto polêmico repleto...

10.1590/s0102-86502006000900008 article PT cc-by Acta Cirúrgica Brasileira 2006-01-01

Urinary incontinence is well documented as a comorbidity of obesity. Studies demonstrate improvement incontinency after weight loss. However, the mechanisms are still not clear.To analyze effects bariatric surgery on pelvic floor function in women.Thirty women were invited to participate. They waiting for surgery. Evaluations done pre-operative period and one year It comprehended: body mass index, urinary prevalence, quality life through King's Health Questionnaire, muscular contraction...

10.1590/s0102-67202012000400010 article EN ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2012-12-01

Objective: To evaluate the influence of end-stage liver disease and orthotopic transplantation in pituitary function hormone metabolism before after transplantation.Methods: In a prospective study, serum levels follicle stimulating (FSH), luteinizing (LH), estradiol (E2) prolactin (PRL) 30 male patients with cirrhosis were determined two to four hours six months transplantation. The results compared according Model for End-stage Liver Disease (MELD).Results: have hypogonadism. FSH was...

10.1590/0100-69912014006007 article EN cc-by Revista do Colégio Brasileiro de Cirurgiões 2014-12-01
Coming Soon ...