Polluted air and the presence of numerous airborne pathogens affect our daily lives. The sensitive fast detection pollutants is crucial for environmental monitoring effective medical diagnostics. Compared to conventional methods (PCR, ELISA, metabolic tests, etc.), biosensors bring a very attractive possibility detect chemicals organic particles with mentioned reliability sensitivity in real time. Moreover, by integrating nanomaterials into biosensor structure, it possible increase...

Abstract Aim To assess the feasibility, safety and efficacy of using a high‐flow nasal cannula (HFNC) for stabilising very preterm infants after birth. Methods A prospective observational study included born at 28 + 0 to 31 6 weeks' gestation between February 2021 December 2022 General University Hospital in Prague. Following delayed cord clamping, HFNC was administered flow rate 8 L/min through infants' nostrils. Criteria switching continuous positive airway pressure (CPAP) or ventilation...

The current generation of neonatal ventilators enables periodic storage set, measured, and calculated ventilatory parameters.

Noninvasive techniques are routinely used for assessment of tissue effects lung ventilation. However, comprehensive studies the response time methods scarce. The aim this study was to compare noninvasive monitoring gas exchange sudden changes in composition inspired gas. A prospective experimental with 16 healthy volunteers conducted. ventilation circuit designed that enabled a fast change inspiratory mixture while allowing spontaneous breathing. inhaled hypoxic mixture, then hypercapnic...

This paper presents a newly-designed and realized Invasive Blood Pressure (IBP) device for the simulation on patient’s monitors. shows improvements extended features with respect to first prototype presented by authors similar systems available in state-of-the-art. A peculiarity of is that all implemented can be customized from developer point view end user. The has been tested, its performances terms accuracy back-loop measurement output blood pressure regulation utilization have described....

In this paper, a new approach for the periodical testing and functionality evaluation of fetal heart rate monitor device based on ultrasound principle is proposed. The design realization are presented, together with description its features functioning tests. designed device, relay element, driven by an electric signal that allows switching at two specific frequencies, used to simulate fetus mother’s heartbeat. simulator was be compliant standard requirements accurate assessment measurement...

Purpose/Aim: High-frequency oscillatory ventilation (HFOV) is a method of that theoretically achieves the goals lung protective in acute respiratory distress syndrome (ARDS) patients. It characterized by rapid delivery small tidal volumes at high frequencies oscillating around continuous distending pressure (CDP). Optimization CDP not an easy task and it titrated empirically clinical practice. The aim this study to investigate whether level consistently affects shape partial oxygen (PaO2)...

<p>Oxygen therapy is an essential treatment of premature infants suffering from hypoxemia. Normoxemia maintained by adjustment the fraction oxygen (FiO<sub>2</sub>) in inhaled gas mixture that set manually or automatically based on peripheral saturation (SpO<sub>2</sub>). Automatic closed-loop systems could be more successful controlling SpO<sub>2</sub> than traditional manual approaches. Computer models neonatal transport have been developed as a...

The aim of the work was to design a metabolic simulator human respiratory system consuming oxygen and producing carbon dioxide. quotient, tidal volume, mechanical parameters other should be similar physiological values in (healthy) men so that could used for simulation artificial ventilation real patients. model consists high-volume plastic box assuring desired lung compliance, propane-butane burner equipped with water-based cooling system, CO2 analyzers "intrapulmonary" gases control...

We are using life-size mannequins within an education subjects, e.g. "Medical devices" for a demonstration of basic principles modern clinical devices such as mechanical lung ventilator. Limitation many simulators is uniformity its outputs same input parameters. This paper describes variability the vital signs mannequin when scenario was used different base patients available at human patient simulator.

The role of high-frequency oscillatory ventilation (HFOV) has long been debated. Numerous studies documented its benefits, whereas several more recent did not prove superiority HFOV over protective conventional mechanical (CV). One the accepted explanations is that CV and act differently, including gas exchange.To investigate a different level coupling or decoupling between oxygenation carbon dioxide elimination during HFOV, we conducted prospective crossover animal study in 11 healthy pigs....

Main purpose of this paper is to describe a propose and compile dynamometric measurement system which would measure the isometric force handgrip. Although, in practice, there have already been mechanic hand dynamometers could evaluate only limited amount information, precisely maximum strength handgrip, our aim full electronic dynamometer. This work focused on design an appropriate hardware software for processing evaluating measured data. By able display graph also actual maximal strength....

Abstract Maintaining a prescribed peripheral oxygen saturation (SpO 2 ) target during routine care of neonates is challenging and inspired fraction (FiO titration practices differ among caregivers centers. Algorithms for automatic feedback control SpO are being developed tested, that would adapt to the changing neonatal organism better maintain required range. While clinical data necessary validate differences in strategies, continuous physiological model oxygenation facilitate baseline...

Medical simulations with whole-body simulators represent a modern and innovative approach in medical education. Interactive human are primarily designed for doctors, nurses other health care personnel. Currently, there many types of available on the market, that differ number simulated parameters costs. We identified several weaknesses to us, namely limited amount palpation sites, missing EEG simulation lack movement after defibrillation shock. The aim this work was extend pulse sites...

Premature newborns often require oxygen support as part of their therapy. Systems for administration are developed to assure adequate oxygenation newborns. Several factors were identified in the systems that contribute time delay between change set inspiratory fraction and its actual delivery tissues. In this study, we aimed reduce physical newborns.We an O2 Flush System (O2-FS) brings source close a patient possible make available rapid compensates ventilator circuit. The O2-FS system is...

Due to the increasing demands of today’s society on visual quality and patient comfort, due growing interest in implantation new more complex intraocular lens (IOL) designs, determining IOL position occupies an important current ophthalmological practice. The dynamic Purkinje meter combines construction static meters, presented recent years, with examination according optical axis IOL.

Abstract The advantages of automatic control the fraction inspired oxygen in neonates have been documented recently published clinical trials. Many algorithms are available, but their comparison is missing literature. A mathematical model neonatal transport could be a useful tool to compare and enhance both manual oxygen. Besides other components, must include module linking arterial (SaO 2 ) peripheral (SpO saturation. pulse oximeter reflect issues SpO measurement typical for practice, such...

Mechanical ventilation is used during respiratory failure in many patients. High-frequency oscillatory as a rescue therapy at adult has minimum monitoring and even tidal volume not routinely measured. Models of the system can contribute to better understanding about principle high-frequency ventilation. The identification simple RLC model described study effect lung compliance upon alveolar pressure discussed. It was shown that reduced minimal whereas it significantly affects an amplitude pressure.