A5062242919- Occupational and environmental lung diseases
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer Cells and Metastasis
- Mitochondrial Function and Pathology
- Fatty Acid Research and Health
- Folate and B Vitamins Research
- Tissue Engineering and Regenerative Medicine
- Cancer Research and Treatments
- Hormonal Regulation and Hypertension
- Metabolism and Genetic Disorders
- S100 Proteins and Annexins
- Clinical Nutrition and Gastroenterology
- Research studies in Vietnam
- Alzheimer's disease research and treatments
- Vitamin C and Antioxidants Research
- Cancer, Lipids, and Metabolism
- Adipose Tissue and Metabolism
- Renal function and acid-base balance
- Evaluation Methods in Various Fields
- Traumatic Brain Injury Research
- Dialysis and Renal Disease Management
Icahn School of Medicine at Mount Sinai
2024
Roskamp Institute
2016-2020
Viet Duc Hospital
2019
Abstract Immunotherapies have shown great promise in pleural mesothelioma (PM), yet most patients still do not achieve significant clinical response, highlighting the importance of improving understanding tumor microenvironment (TME). Here, we utilized high-throughput, single-cell RNA sequencing (scRNA-seq) to de novo identify 54 expression programs and construct a comprehensive cellular catalog PM TME. We found four cancer-intrinsic associated with poor disease outcome novel fetal-like,...
Mục tiêu: Mô tả tình trạng dinh dưỡng và một số yếu tố liên quan tới của phụ nữ có thai đến khám tại Bệnh viện E năm 2024. Phương pháp: Nghiên cứu cắt ngang được tiến hành từ tháng 8/2024 10/2024, phỏng vấn 111 theo bộ câu hỏi thiết kế sẵn cân, đo nhân trắc. Kết quả: Trước khi mang thai, tỷ lệ thiếu năng lượng trường diễn là 15,3%, thừa cân 12,6%. quả sàng lọc 35,1% nguy cơ suy vừa; 7,2% nặng. Tỷ tăng dưới khuyến nghị 66,7%, trên 12,9%. Các tuổi mẹ ³ 35 (OR=2,9; 95%CI: 1,1-7,3; p<0,05),...
The contribution of apolipoprotein E (APOE) E4 to the cerebrovascular dysfunction in Alzheimer's disease (AD) is characterized by presence severe cerebral amyloid angiopathy, increased blood-brain-barrier (BBB) breakdown, reduced vascularization, and basement membrane thinning carriers compared non-carriers. It has also been proposed that diminished capacity apoE4 protein transport essential polyunsaturated fatty acids (PUFAs) are required for structural functional maintenance vascular...
<p>Molecular dissection of T cell programs and IC molecules shows association with scS-score</p>
<p>Fetal-like, cancer-specific PLVAP+ endothelial cells associate with angiogenesis</p>
<p>NK cell IC blockade targeting NKG2A as a novel therapeutic strategy in PM</p>
<div>Abstract<p>Immunotherapies have shown great promise in pleural mesothelioma (PM), yet most patients still do not achieve significant clinical response, highlighting the importance of improving understanding tumor microenvironment (TME). Here, we utilized high-throughput, single-cell RNA sequencing (scRNA-seq) to <i>de novo</i> identify 54 expression programs and construct a comprehensive cellular catalog PM TME. We found four cancer-intrinsic associated with poor...
<p>Unbiased discovery of PM cancer programs and association with patient survival</p>
<p>Macrophages in scS-high PM express CXCL9/10/11 and likely contribute to T-cell infiltration</p>
<p>Single-cell catalogue of PM tumor and PBMC samples</p>
The apolipoprotein (APOE) e4 allele is one of the strongest genetic risk factors for Alzheimer’s disease (AD). While apoE4 protein well known its limited capacity to transport lipids, little examination has been performed on blood lipids in context status and their collective contributions AD. Lipidomic analyses were serum samples from a longitudinal cohort cognitively normal subjects, subset whom converted mild cognitive impairment (MCI)/AD within 2 3 years. To examine relation APOE...
Ahmed, B.1; Bisotto, S.1; Michel, C.1; Nguyen, T.2; Schiller, P. W.1; Lavoie, J. L.1Author Information
Hyperphosphatemia and dyslipidemia are the important modifiable risk factors for cardiovascular disease in patients with end-stage renal diseases. is associated increased mortality among dialysis patients. Non-calcium phosphate binders lipid lowering agents not frequently used developing countries due to limited resources. Various additional treatments can add value controlling these conditions reduce cost. The aim of this study was assess effect nicotinic acid on hyperphosphatemia...