A5082652419- Endodontics and Root Canal Treatments
- Dental Trauma and Treatments
- Dental materials and restorations
- Immune Response and Inflammation
- Bone and Dental Protein Studies
- dental development and anomalies
- Oral microbiology and periodontitis research
- Laser Applications in Dentistry and Medicine
- Inflammasome and immune disorders
- Oral and Craniofacial Lesions
- Periodontal Regeneration and Treatments
- NF-κB Signaling Pathways
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Oral and Maxillofacial Pathology
- Inflammatory mediators and NSAID effects
- Dental Implant Techniques and Outcomes
- Mesenchymal stem cell research
- Dental Erosion and Treatment
- interferon and immune responses
- Dental Radiography and Imaging
- Oral health in cancer treatment
- Bone Metabolism and Diseases
- Oral Health Pathology and Treatment
- Gout, Hyperuricemia, Uric Acid
- Pancreatic and Hepatic Oncology Research
Universidade de São Paulo
2016-2025
Universidade de Ribeirão Preto
2016-2024
Abstract Aim To assess the efficacy of treatment using a minimally invasive approach (selective removal carious tissue, restoration and preventive strategies) in immature permanent molars with MIH. Design A total 281 patients, aged 6‐8 years, lesions (ICDAS 5‐6), severe MIH, incomplete root formation (one tooth/patient) were included. After clinical radiographic examinations, selective tissue was performed, teeth received interim for 6 months then restored composite resin. Clinical follow‐up...
To evaluate and correlate, in the same research, mRNA expression staining of RANK, RANKL, OPG, TLR2 MyD88 by immunohistochemistry apical periodontitis (AP) progression mice.AP was induced lower first molars thirty-five C57BL/6 mice. They were assigned to four groups according their euthanasia periods (G0, G7, G21 G42). The jaws removed subjected histotechnical processing, real-time reverse transcription-PCR (qRT-PCR). Data analyzed with parametric nonparametric tests (α=0.05).An increase...
To quantify M1 and M2 macrophages in radicular cysts of permanent (n = 14 cases) primary teeth 15 cases).All patients who attended the School Dentistry Ribeirão Preto, University São Paulo with or molars that were scheduled for extraction fulfilled inclusion criteria: absence pain; presence/absence fistulae; extensive coronal destruction due to caries lesions without possibility restoration; pulp necrosis; radiographically visible apical periodontitis; no previous treatment, selected. The...
This study evaluated physiochemical proprieties of a calcium hydroxide-based paste (Calen®) combined with zinc oxide cement at different ratios (1:0.5, 1:0.65, 1:0.8 and 1:1). Materials were compared regarding setting time, pH variation, radiopacity, solubility, dimensional changes, flow release chemical elements. Data analyzed statistically by ANOVA Tukey's test (α=0.05). Longer time higher changes solubility values exhibited 1:0.65 1:0.5 (p<0.05). The the highest all points. All materials...
The aim of this study was to evaluate the IFI16 and IFN-α/β receptors expression during genesis development experimental apical periodontitis (AP) in mice teeth.Apical induced lower first molars 40 C57BL/6 mice. They were divided according periods 2, 7, 14, 21 42 days (n = 8 per group). Five animals used as a control group (without AP). Specimens submitted histological processing for description inflammatory process, immunostaining presence/absence localization (qualitative semi-quantitative...
Abstract Background/Aim The extra‐alveolar dry period and storage medium in which a tooth is kept prior to replantation remain critical factors affecting the survival repair potential of periodontal ligament avulsed teeth. When not immediate, replacement root resorption ( RRR ) most common complication. aim this histological study was evaluate effect immediate controlled‐orthodontic forces healing replanted teeth canine model. Material Methods Sixty maxillary mandibular premolar roots were...
Aim: To compare the apical negative pressure irrigation (ANP) with conventional in teeth of immature dogs periodontitis. Methods: Fifty-two pre-molar root canals were randomly assigned into 4 groups: ANP (n=15); (n=17); healthy (control) (n = 10); and untreated periodontitis (n=10). After induction periodontitis, instrumented using EndoVac® (apical irrigation) or irrigation. The animals euthanized after 90 days. sections stained by HE analyzed under fluorescence microscopy. TRAP...
The COVID-19 pandemic led to changes in academic teaching and dental education, but the impact on professors' mental health quality of life remains poorly understood. Thus, objective this study was evaluate impacts social distancing online related anxiety Brazilian professors. This a cross-sectional conducted from August 2020 October 2020. Three instruments were used an version: questionnaire about personal data, information activities, Generalized Anxiety Disorders 7 (GAD7) scale,...
The aim of this study was to evaluate the subcutaneous connective tissue response isogenic mice exposed tricalcium silicate (Biodentine) and aggregated mineral trioxide (ProRoot MTA). A total 120 were divided into 4 groups in 3 different experimental periods (7, 21 63 days): Biodentine; Pro-Root MTA; zinc oxide-eugenol and; Negative control - Sham. After microscopic descriptive, semi-quantitative quantitative analysis inflammatory process analyzed on H&E sections evaluation gene expression...
The aim of this study was to evaluate the subcutaneous connective tissue response isogenic mice after implantation different glass ionomer-based cements (EQUIA® Forte Fil, EQUIA® Fil and Ketac™ Universal Aplicap™). Eighty-seven BALB/c were allocated in 12 groups, 9 considered as experimental groups (Ketac, E. at 7, 21 63 days) 3 controls (empty polyethylene tubes days). After periods, surrounding implanted material removed subjected histotechnical processing staining with hematoxylin eosin....
Periodontal destruction can be the result of different known and yet-to-be-discovered biological pathways. Recent human genetic association studies have implicated interferon-gamma inducible protein 16 (IFI16) absent in melanoma 2 (AIM2) with high periodontal interleukin (IL)-1β levels more destructive disease, but mechanistic evidence is lacking. Here, we sought to experimentally validate these observational associations better understand IFI16 AIM2's roles periodontitis.Periodontitis was...
The color stability and surface uniformity are very important properties for dental aesthetics. Objective: To evaluate the roughness of different composites after artificial accelerated aging (AAA). Methods: Samples were made using silorane-based Filtek P90 (3M-ESPE), nanohybrid Tetric N-Ceram (Ivoclar Vivadent), GC Kalore (GC Company). Ceramic D. Sign Vivadent) Ketac N100 (3M-ESPE) resin-modified glass ionomer cement (RMGIC) served as controls. values recorded before AAA non-C-UV (300...
<title>Abstract</title> Objectives The present study evaluated the phenotypic characterization of M1 and M2 macrophage subtypes during development periapical lesion (PL). Materials Methods PL was induced in lower first molars 96 mice. After experimental periods 2, 7, 14, 21, 42 days, animals were euthanized jaws dissected submitted to following analyzes: microscopic descriptive analysis fluorescence microscopy morphometry size (mm<sup>2</sup>); quantitative gene expression by qRT-PCR for...
Abstract To evaluate the inflammatory tissue response to BioRoot™ RCS (BR) and AH Plus Jet (AHPJ) sealers implanted in mice subcutaneous tissue. It was hypothesized that BR would be milder than AHPJ. An vivo study carried out using isogenic mice. The were during standardized surgical procedures. evaluated by microscopic analysis von Kossa reaction reactionary around specimens after 7, 21, 63 days. For comparisons, a zinc oxide eugenol sealer (ZOE) used as positive control, addition negative...
Purpose: Recent studies have suggested that disruptions in the RANKL/RANK/OPG system might be involved enamel conditions. The aim of this study was to test whether genetic polymorphisms RANK, RANKL and OPG are associated with dental caries, developmental defects (DDE) microhardness. Study design: Saliva samples were collected from two subsets for purpose genomic DNA extraction. In first subset, composed 248 children, caries DDE evaluated during their clinical examination. second 72 buccal...
The objective of this in vivo study was to assess the effect root canal irrigation by negative and positive apical pressure on expression molecules that are an indicative cell differentiation with mineralizing phenotype teeth dogs incomplete rhizogenesis induced periapical lesion. A total 30 (60 roots) were distributed into 3 groups (n=20): EndoVac®, Conventional Control. After 90 days, routine histotechnical procedures performed sections submitted immunohistochemical technique for staining...
The high rate of root resorption resulting from tooth replantation represents a serious clinical problem. In order to prevent ankylosis and replacement resorption, the contemporary literature highlights importance using flexible stabilization for traumatized teeth. For this purpose, orthodontic devices may be promising obtaining better prognosis periodontal repair. aim study was evaluate effect an active splinting protocol with controlled force in dog's teeth following replantation.Sixty...