A5031591582- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- S100 Proteins and Annexins
- Moyamoya disease diagnosis and treatment
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Cell Adhesion Molecules Research
- Acute Ischemic Stroke Management
- Bone and Dental Protein Studies
- Connective tissue disorders research
- Cardiovascular Health and Disease Prevention
- Oropharyngeal Anatomy and Pathologies
- Tracheal and airway disorders
- Aortic aneurysm repair treatments
- Neurological Complications and Syndromes
- Bacterial Infections and Vaccines
- Infective Endocarditis Diagnosis and Management
- Galectins and Cancer Biology
- Reconstructive Surgery and Microvascular Techniques
- Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
Kobe Kaisei Hospital
2021-2023
Mie University
2013-2022
Mie University Hospital
2017-2018
Mie Chuo Medical Center
2016-2017
National Hospital Organization
2016-2017
Naga Municipal Hospital
2006-2008
JGC (Japan)
1990
OBJECT Tenascin-C (TNC), a matricellular protein, is induced in the brain following subarachnoid hemorrhage (SAH). The authors investigated if TNC causes edema and blood-brain barrier (BBB) disruption experimental SAH. METHODS C57BL/6 wild-type (WT) or knockout (TNKO) mice were subjected to SAH by endovascular puncture. Ninety-seven randomly allocated WT sham-operated (n = 16), TNKO 34), 31) groups. Mice examined means of neuroscore water content 24-48 hours post-SAH; Evans blue dye...
This study aimed to predict recurrence after coil embolization of unruptured cerebral aneurysms with computational fluid dynamics (CFD) using porous media modeling (porous CFD).A total 37 treated coiling were analyzed follow-up angiograms, simulated CFD prior (control CFD), and CFD. Coiled classified into stable or groups according angiogram findings. Morphological parameters, packing density, hemodynamic variables evaluated for their correlations aneurysmal recurrence. We also calculated...
Background & purpose Hyperplastic remodeling (HR) lesions are sometimes found on cerebral aneurysm walls. Atherosclerosis is the results of HR, which may cause an adverse effect surgical treatment for aneurysms. Previous studies have demonstrated that atherosclerotic changes had a correlation with certain hemodynamic characteristics. Therefore, we investigated local characteristics HR aneurysms using computational fluid dynamics (CFD). Methods Twenty-four were CFD and intraoperative video...
Background: Tenascin-C (TNC) has been reported to be a useful biomarker for the activity of inflammatory diseases. This study investigated association between TNC levels in cerebrospinal fluid (CSF) and symptomatic vasospasm after aneurysmal subarachnoid hemorrhage (SAH), prognostic value levels. Methods: were measured CSF 33 consecutive patients diagnosed with SAH Fisher computed tomography group III compared those without subsequent cerebral vasospasm. Factors influencing determined using...
OBJECT Histopathological examination has revealed that ruptured cerebral aneurysms have different hemostatic patterns depending on the location of clot formation. In this study, authors investigated whether had specific hemodynamic features using computational fluid dynamics (CFD) analysis. METHODS Twenty-six middle artery were evaluated by 3D CT angiography and harvested at time clipping. The rupture points assessed means histopathological examination, morphological parameters obtained....
Subarachnoid hemorrhage (SAH) is a devastating disease. Neuronal death an important pathophysiology in the acute phase of SAH, but histopathological features dying neurons have been poorly studied. Using several staining methods including terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and microtubule-associated protein 2 (MAP-2) double immunolabeling, we investigated morphological changes nucleus cytoskeleton sought susceptible areas to neuronal filament perforation SAH...