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Gabrielle Costlow

ORCID: 0000-0003-4882-0182
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About
Contact & Profiles
A5045081060
Research Areas
  • IL-33, ST2, and ILC Pathways
  • Renal cell carcinoma treatment
  • Organ Donation and Transplantation
  • Renal and related cancers
  • Galectins and Cancer Biology

University of Virginia
 2021-2024

Virginia Commonwealth University
 2023

 ST2+ T-regulatory Cells in Renal Inflammation and Fibrosis following Ischemic Kidney Injury
OPENALEX - Publications 
Vikram Sabapathy AJ Price Nardos Tesfaye Cheru Rajkumar Venkatadri Murat Doğan and 3 more Gabrielle Costlow Saleh Mohammad Rahul Sharma

Key Points IL-33/ST2 alarmin pathway regulates inflammation, fibrosis, and resolution of ischemia-reperfusion injury kidneys. ST2 the transcriptome T-regulatory cells related to suppressive reparative functions. The secretome + hypoxic in an amphiregulin-dependent manner. Background Inflammation is a major cause kidney injury. IL-1 family cytokine IL-33 released from damaged modulates immune response through its receptor expressed on many cell types, including regulatory T (Tregs). Although...

10.1681/asn.0000000000000471 article EN Journal of the American Society of Nephrology 2024-08-26
 Novel Role of ST2+ Tubular Cells in Shaping Immune Microenvironment
OPENALEX - Publications 
Vikram Sabapathy Gabrielle Costlow Franklin Jebaraj Herbert Bushra Mehkri Saleh Mohammad and 1 more Rahul Sharma

10.1681/asn.20233411s1683c article EN Journal of the American Society of Nephrology 2023-11-01
 IL-33 (Interleukin 33)/ST2 (Interleukin 1 Receptor-Like 1) “Alarmin” Signaling Axis Regulates Innate Immune Response in Kidney Injury
OPENALEX - Publications 
Vikram Sabapathy Gabrielle Costlow Saleh Mohammad Sanja Arandjelovic Rahul Sharma

Sabapathy, Vikram; Costlow, Gabrielle; Mohammad, Saleh; Arandjelovic, Sanja; Sharma, Rahul Author Information

10.1681/asn.20223311s1586c article EN Journal of the American Society of Nephrology 2022-11-01
 Modeling ST2/IL-33 “Alarmin” Signaling Through Kidney Organoid-Immune Cell Co-Culture System
OPENALEX - Publications 
Vikram Sabapathy Gabrielle Costlow Saleh Mohammad Rahul Sharma

Sabapathy, Vikram; Costlow, Gabrielle; Mohammad, Saleh; Sharma, Rahul Author Information

10.1681/asn.20223311s1425d article EN Journal of the American Society of Nephrology 2022-11-01
 IL-33/ST2 Alarmin Signaling Axis in Myeloid Cells Regulates Kidney Injury
OPENALEX - Publications 
Vikram Sabapathy Gabrielle Costlow Nardos T. Cheru A. P. Price Rajkumar Venkatadri and 3 more Murat Doğan Saleh Mohammad Rahul Sharma

Sabapathy, Vikram; Costlow, Gabrielle; Cheru, Nardos T.; Price, Airi; Venkatadri, Rajkumar; Dogan, Murat; Mohammad, Saleh; Sharma, Rahul Author Information

10.1681/asn.20213210s1163b article EN Journal of the American Society of Nephrology 2021-10-01
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