A5016067447- Cardiovascular and Diving-Related Complications
- Diabetic Foot Ulcer Assessment and Management
- Injury Epidemiology and Prevention
- Acute Ischemic Stroke Management
- Restraint-Related Deaths
- Respiratory Support and Mechanisms
- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Bone and Joint Diseases
- Trauma Management and Diagnosis
- Cancer, Hypoxia, and Metabolism
- Sinusitis and nasal conditions
- Botulinum Toxin and Related Neurological Disorders
- Barrier Structure and Function Studies
- Head and Neck Surgical Oncology
- Neuroscience of respiration and sleep
- Glioma Diagnosis and Treatment
- Pneumothorax, Barotrauma, Emphysema
- Reconstructive Surgery and Microvascular Techniques
- Organ Transplantation Techniques and Outcomes
- Autopsy Techniques and Outcomes
- Mesenchymal stem cell research
- High Altitude and Hypoxia
- Cardiac Arrest and Resuscitation
- Colorectal Cancer Surgical Treatments
Istanbul University
2011-2022
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2013
National Hyperbaric Centre
2012
The effects of hyperbaric oxygen (HBO) therapy on oxidant/antioxidant metabolism are controversial and its hepatic regeneration not known. In this study, we investigated a possible beneficial effect HBO oxidant antioxidants levels during liver regeneration. To conduct seventy percent hepatectomy was performed forty-eight Spraggue-Dawley rats the were divided into two equal groups: HBO-treated group untreated (non-HBO group). We determined malondialdehyde (MDA), an oxidative stress marker,...
Temozolomide (TMZ) has anti-tumor activity in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are limited because hypoxic tumor microenvironment. We examined combined effects TMZ-HBO a rat glioma model.After stereotactic injection C6/LacZ cells into Wistar rats brain, were randomly assigned to three treatment groups [group 1, control treatment; group 2, TMZ alone; 3, combination and HBO]. Rats sacrificed 18 days after treatment,...
Objective: The functional evaluation of the effect hyperbaric oxygen therapy (HBOT) onset time on cochlea by using distortion product otoacoustic emission. Study Design: Animal study. Methods: Twenty-four Wistar albino rats were divided into six groups and their right ears directly exposed to a 110-dB sound pressure level (1-12 kHz) white noise for 25 minutes. first group was considered control group. HBOT started at 1 hour postexposure second group, 2 hours third 6 fourth 24 fifth 48 sixth...
Adriamycin extravasation is a serious problem that can lead to severe local necrosis and damage underlying nerves, tendon, muscle. There are some experimental studies in which conflicting results were reported about the beneficial effects of hyperbaric oxygen (HBO) adriamycin-induced skin lesions. In this study effect HBO on healing wounds was investigated Wistar-Albino rat model. Ninetyfive rats underwent injection 0.7-ml adriamycin solution (2 mg per milliliter) subcutaneously right upper...
Inhalation of 100% oxygen in a hyperbaric chamber has been accepted as useful treatment for patients with various pathologies who suffer from hypoxia. The oxidative effects (HBO) on RBCs have investigated animals but there is not enough data hemorheological paramet ers following HBO (HBOT). In this study, we the effect and haematological parameters during treatment. Red blood cell (RBC) deformability aggregation, plasma viscosity superoxide dismutase activity were underwent HBOT....
Due to the increasing popularity in recreational diving long-term health consequences of this sport have aroused interest community. Although not as important dysbaric osteonecrosis, ischemic brain lesions, or neurophysiological symptoms, paranasal sinus mucosal hypertrophy (PSMH) has also been discussed being more prevalent among divers. In study, we used magnetic resonance imaging (MRI) compare asymptomatic divers with control subjects for PSMH.We enrolled 79 male (34.0 +/- 5.7 yr) and...
In this study, we investigated the effect of hyperbaric oxygen therapy (HBOT) on morphology estradiol valerate (EV) induced polycystic ovary (PCO) to find a new treatment modality for improvement PCO. The rats were divided into four groups. Group1, control; group 2, PCO group; 3, with HBOT and 4, normal HBOT. was by single intramuscular injection 4 mg EV in adult cycling rats. Other ovaries had oil as placebo. applied third fourth groups six weeks. Histopathologic evaluation all performed &...
The snorkel, which allows swimmers to keep their face down in the water while breathing, is widely used by divers, spear fishermen and monofin swimmers. A snorkel adds an additional dead space of 160 - 170 ml causes increase concentration CO2 inspired gas due expired air trapped then re-inspired. In this study metabolic ventilatory response rebreathing were investigated twelve human subjects. 2900 C Sensor Medics analyzer was breath-by-breath mode for measurements. Ventilation (VE),...
Cisplatin is an antineoplastic agent, used in the treatment of different types malignant neoplasms. Side effects such as ototoxicity, nephrotoxicity, and bone marrow toxicity are main limitations its clinical use. The aim present study was to evaluate possible hyperbaric oxygen (HBO) therapy a protective agent cisplatin-induced ototoxicity rats.A total 30 adult Wistar rats (60 ears) were divided into five equal groups. Group 1 control group; group 2 HBO 3 received 15 mg/kg cisplatin...
Pulmonary barotrauma (PBT) is a recognised risk of compressed gas diving. Any reason that causes air trapping in the lung during ascent may cause PBT by increasing intrapulmonary pressure. Chest x ray examination mandatory for medical certification professional divers many countries, but pulmonary lesions such as an cyst lungs cannot always be detected plain chest examination. Computed tomography (CT) reliable, expensive measure detecting abnormalities divers. Three cases with cysts are...
Dysbaric osteonecrosis (DON) is regarded as an occupational disease for caisson workers, commercial, and military divers. Magnetic resonance imaging (MRI) was suggested the surveillance of divers DON. This study aimed to determine prevalence DON in Turkish Navy divers.The shoulder, hip, knee joints 106 male were screened with MRI. A questionnaire used obtain information about subjects' medical history diving experience.The mean age 34.3 +/- 5.8 yr. The had spent average 12.1 6.1 yr at their...
OBJECTIVE: Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal ischemic colonic anastomoses in rats.METHODS: Eighty male Wistar rats were divided into eight groups (n = 10).In first four groups, nonischemic anastomosis performed, whereas remaining performed.In 5, 6, 7, 8, ischemia established by ligating 2 cm mesocolon either side anastomosis.The control (1 5) received no treatment.Hyperbaric initiated immediately after surgery...