A5010276364- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Reproductive Health and Technologies
- Reproductive System and Pregnancy
- Ovarian function and disorders
- COVID-19 Impact on Reproduction
- Sexual Differentiation and Disorders
- Reproductive biology and impacts on aquatic species
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Physiology in Livestock
- Seed Germination and Physiology
- Preterm Birth and Chorioamnionitis
- COVID-19 and healthcare impacts
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Iran University of Medical Sciences
2019-2023
Isfahan University of Medical Sciences
2014
University of Tehran
2014
The DNA integrity of spermatozoa that attach to fallopian tube (FT) cells is higher than do not attach. FT epithelial can distinguish normal and abnormal sperm chromatin. This study investigated the effects with a high-DNA fragmentation index (DFI) from men unexplained repeated implantation failure (RIF) on Toll-like receptor (TLR) signaling pathway in human vitro.Ten RIF history high-DFI 10 healthy donors low-DFI comprised (>30%) control (<30%) groups, respectively. After fresh semen...
Although the role of myo-inositol (MYO) in promoting oocyte quality PCOS patients has been documented human studies; cellular effects this supplement on oocytes have not directly examined due to ethical limitations. In first phase study, MYO dosimetry was carried out simultaneously with model development. An effective dose obtained following assessment fasting insulin and testosterone levels using ELISA ovarian morphology appraisal by histopathology. second phase, continuous administration...
Spermatogenesis is a process in which animals generate spermatozoa from spermatogonial stem cells (SSCs). Successful vitro differentiation of SSCs towards spermatids holds significant promise for regeneration impaired spermatogenesis. The present study aims to evaluate the efficiency 3D culture containing naringenin on proliferation and potentials mouse SSCs. In this study, multi‐walled carbon nanotubes (MWCNTs) were incorporated into poly( l ‐lactic acid) (PLLA) fibers via electrospinning...
Background: In about 40% of the couples, cause infertility problems is attributed to men because low sperm production and disturbed motility sperm. Pieces evidence show that Myo-inositol has a potential role for treatment morphology male fertility. Objectives: This study aimed determine effect on parameters fertility rate in patients with oligoasthenospermia treated by intrauterine insemination (IUI). Materials Methods: was randomized clinical trial conducted 37 IUI during 2016-2017. this...
Background: Hormonal imbalance is one of the important etiological factors for Oligoasthenoteratospermias (OAT). Objective: This study aimed to evaluate effects hormonal changes including prolactin, TSH, testosterone, luteinizing hormone, follicle-stimulating and anti-Mullerian hormone on sperm DNA fragmentation in normal men compared with OAT design a clinical algorithm comprehensive male factor infertilities. Materials Methods: We consecutively selected 60 candidates referred infertility...
There is a correlation between teratozoospermia and production of reactive oxygen species leading to poor assisted reproductive techniques outcomes. This study aimed examine the effect plasma-rich in growth factors (PRGF) on teratozoospermic samples. Twenty-five samples were included this study. After sperm preparation, it was divided into four groups, including 0 (control), 1, 5, 10% PRGF. Sperm motility, viability (eosin-nigrosin staining), morphology (Papanicolaou DNA fragmentation (sperm...
The cryopreservation-thawing process of spermatozoa cells has negative impacts on their structure, function, and fertility parameters, which are known as cryoinjury. Asthenozoospermia patients more susceptible to Granulocyte-macrophage colony-stimulating factor (GM-CSF) increases sperm glucose uptake via the induction transporters, resulting in increased motility. This study aimed investigate efficiency GM-CSF supplementation cryopreservation media for semen samples asthenoteratozoospermia...
Although intracytoplasmic sperm injection (ICSI) is a way to deal with in vitro fertilization failure, 3% of couples still experience repeated failure after attempted ICSI, despite having within normal parameters. These patients are challenging group whose cannot fertilize the egg during ICSI. Unfortunately, no test can predict risk failure. Phospholipase C zeta (PLCζ) and transition nuclear proteins (TNPs) essential factors for chromatin packaging maturation. This study aimed assess PLCζ1...
Abstract Study question Can GM-CSF as a sperm medium supplement improve quality in OAT men? Summary answer can be used to men by activating the PI3K/Akt pathway. What is known already patients have very low parameters, including morphology, count, and motility, which adversely affect results of assisted reproduction technologies. It seems development media necessary parameters these patients. natural growth factor produced reproductive organs, culture supplemented with widely commercially...
Abstract Study question Which sperm preparation technique separate the best quality sperm? Summary answer Microfluidic method improved parameters and decreased DNA damage. What is known already About 40% of infertility issues are due to male factor. One causes associated with low high level fragmentation. Sperm techniques in ICSI procedures used order obtain best-quality sperm. design, size, duration The present study was designed compare Microfluidic, Zeta potential, Magnetic Activated Cell...