Daniel T. Applegate

ORCID: 0000-0003-4904-5165
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About
Contact & Profiles
Research Areas
  • Pain Mechanisms and Treatments
  • Evolution and Paleontology Studies
  • Pancreatic function and diabetes
  • Neuroscience of respiration and sleep
  • Animal Vocal Communication and Behavior
  • Diet and metabolism studies
  • Inflammatory mediators and NSAID effects
  • Bat Biology and Ecology Studies
  • Physiological and biochemical adaptations
  • Osteoarthritis Treatment and Mechanisms
  • Diet, Metabolism, and Disease
  • Mitochondrial Function and Pathology

University of Illinois Chicago
2017-2021

Safe anaerobic metabolism Naked mole-rats live in large colonies deep underground hypoxic conditions. Park et al. found that these animals fuel glycolysis with fructose by a rewired pathway avoids tissue damage (see the Perspective Storz and McClelland). These results provide insight into adaptations this strange social rodent has to make for life underground. They also have implications medical practice, particularly understanding how protect tissues from hypoxia. Science , issue p. 307 ; see 248

10.1126/science.aab3896 article EN Science 2017-04-20

Naked mole-rats are extremely social and vocal rodents, displaying a wide range of functionally distinct call types vocalizing almost continuously. Their vocalizations low frequency, behavioral audiogram has shown that naked mole-rats, like other subterranean mammals, hear only frequencies. Hence, the frequency their hearing appears to be well matched. However, even at frequencies, show very poor auditory thresholds, suggesting communication may effective over short distances. in tunnel...

10.1007/s00359-018-1287-8 article EN cc-by Journal of Comparative Physiology A 2018-09-19
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