Background: Pituitary adenomas (PAs) are the most prevalent neuroendocrine tumour. Inflammation, both within tumour microenvironment and systemically, plays a role in biology. Haematological laboratory data serves as an initial cost-effective approach. This study explores association between haematological indices (e.g., NLR, PLR, LMR) PA characteristics (tumour size, sellar erosion, cavernous sinus invasion). Methods: A retrospective (2018–January 2023) analysed preoperative (such...

Background: The current World Health Organization (WHO) 2021 classification of human glioma is based on key molecular biomarkers to define neoplastic entities. This review further delineates mutant IDH (isocitrate dehydrogenase) from wild-type disease, a necessity given the large survival gap between and tumors. In Indonesia, there are currently few reports distribution significance these mutations. Therefore, this research aims determine relationship mutations, as well clinicopathological...

Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus not feasible. We are presenting our experience treating intractable epilepsy patients by CCT procedures.We observed 16 who underwent (male female ratio 7:9; adult pediatric 3:13). Initial seizure frequency was reported ranged from 1 2 daily very often (more than 20 episodes daily).Our observation showed that among with attacks,...

Hemispherotomy is a surgical treatment indicated in patients with drug-resistant epilepsy due to unilateral hemispheric pathology. less invasive compared hemispherectomy. We reviewed our experience performing 24 hemispherotomy and report the results of 16 prolonged follow-up this relatively uncommon procedure two centers Indonesia. This retrospective observational study conducted from 1999 July 2019 neurosurgical Semarang, Surgical techniques included vertical parasagittal (VPH),...

Background: Exposure of the shunt is a rare but severe complication after ventriculoperitoneal (VP) placement. It unclear whether particular levels cerebrospinal fluids (CSF) protein, glucose, or polymorphonuclears (PMNs) may influence the shunt exposure in high-risk individuals.This study aims to find relation between CSF parameters and exposure.Methods: Examined preoperative characteristics included colour, PMNs content 513 patients with hydrocephalus. Mann-Whitney test was used...

Introduction: The main objective of the surgical procedure is to achieve maximum resections with minimal functional neurological deficits for patient intrinsic tumors near eloquent cortical area. awake craniotomy currently key option achieving optimum safe resection. We report our two years experience in establishing an Kariadi General Hospital, evaluating adoption technique and outcome surgery.Methods: This a retrospective study analyzed data from all patient's medical records, who have...

Abstract Approximately 26–30% of temporal lobe epilepsy (TLE) cases display a normal-appearing magnetic resonance image (MRI) leading to difficulty in determining the epileptogenic focus. This causes challenges surgical management, especially countries with limited resources. The medical records 154 patients MRI TLE who underwent surgery between July 1999 and 2019 our centre Indonesia were examined. primary outcome was Engel classification seizures. Anterior lobectomy performed 85.1%...

Background: Meningioma is a pathological condition in the central nervous system (CNS), while obesity defined as excess fat accumulation body, which associated with adverse effects on health. Obesity characterized by an increase Body Mass Index (BMI) and Waist Hip Ratio (WHR). Research relationship of BMI, WHR meningioma has been widely carried out various countries Europe, however, it not done much Asian countries, especially Indonesia. Objective: To prove BMI risk factors for incidence...

Introduction: Spinal tumors are rare lesions. The incidence of spinal is about 0.5-2.5 cases per 100,000 population year.1 Thirty percent located intradural. Twenty to thirty intradural schwannoma and neurofibroma.2 Surgery the leading choice for schwannomas neurofibromas that grow progressively or cause neurological deficits.2,3,4 Currently, minimally invasive surgery developing rapidly, including on spine surgery.Better outcomes expected in endoscopic compared conventional techniques.This...

Background: Even with optimized anti-epileptic medications, 30% of epilepsy patients will be refractory and this condition leads to cognitive psychosocial decline, resulting in worse quality life higher mortality. With 0,75% prevalence, there are more than 2.0 million epileptic Indonesia, about 360.000 refractory, half them potential candidates for surgery (ES). After 17 years since the first ES on July 1999, number increases every year reaching around 50 cases per year. By end 2017, Â total...

Objective: Among imaging modalities, ultrasonography (US) is one of the most versatilechoice, with its low cost, lack radiation exposure, and minimally disrupted surgery flow.We described use characteristics intraoperative in selectedcases our center to assist intracranial tumor resection.
 Methods :Seventy patients wereoperated from 2011 2018 at Kariadi Hospital help US. Fifty sixpercents cases were cystic tumors, 25% abscess 19% metastatic tumors Weused seven parameters measure...

Meningioma is a tumor that developed from arachnoid caps cell and growing at any site inside the cranium, tuberculum sellae meningioma one of them. Surgery without damaging brain primary goal. One important point in successful operation meningiomas surgery approach. There are many approaches meningioma. Our department uses three to remove tumor: supraorbital, subfrontal unilateral interhemispheric, subfrontal/frontobasal. The consideration choosing approach based on risk benefit according...

Abstract Objective: The IDH1 mutation status is one of the main factors indicated prognosis patients with astrocytic malignancies; yet, targeted sequencing not readily available in countries limited resources. We aimed to analyze association between examination and overall survival rates diffuse tumor patients. Methods: This retrospective cohort multicenter study included 327 patients, January 2017 – December 2022. immunohistochemistry or PCR data MGMT status, WHO classification, Karnofsky...

Introduction: Cavernous malformations of the brainstem are groups dilated sinusoidal tracts. The surgical excision cavernous abnormalities is high-risk and challenging. Clinical manifestations due to mass effect or hemorrhage, as well MRI studies, have become valuable factors in determining most appropriate procedure for cavernoma achieve safe entry zone brainstem. Case: A case report on a reported here. 10-year-old male with pontomesencephalic presented. was surgically removed using lateral...

Link of Video Abstract: https://youtu.be/JhROjWPKuAc Background: Primary spinal cord tumors are rare central nervous system that could develop at any age and have different management strategies based on the histopathological types. However, there is a lack literature in Indonesia regarding epidemiology surgical treatment patients with tumors. This study aims to review address incidence primary Dr. Kariadi Hospital, Semarang. Methods: A retrospective descriptive was conducted using medical...

Penetrating cervical spinal cord injury (SCI) is a rare clinical entity that requires multitude of health care specialists for proper management. The unpredictable nature penetrating SCI and complex systemic sequela contribute to the high mortality rates SCI. An 18-year-old-male patient was admitted emergency department with tetraparesis following neck. Radiological examination revealed fractures C4 C5 spinous processes extensive intradural pneumorrhachis. managed operatively laminectomy,...

Latar belakang: Glioblastoma (GBM) berhubungan dengan peningkatan hiperkoagulabilitas dan risiko dari venous thromboembolism (VTE) (termasuk Deep Vein Thrombosis (DVT)). VTE merupakan komplikasi kardiovaskular atau respirasi yang sering ditemukan pada pasien-pasien dirawat inap karena COVID-19. Hubungan mengenai kasus GBM COVID-19 belum pernah dibahas sebelumnya. Laporan ini akan membahas tentang seorang wanita usia 55 tahun DVT hasil PCR SARS-CoV-2 positif di RSUP Dr. Kariadi.
 kasus:...

Background : High grade Gliomas (HGGs) (World Health Organization III and IV) are aggressive brain tumors with a poor prognosis. Serum concentrations of GFAP EGFR theoretically raised in glioma patients, especially primary HGGs
 Aim To look at serum levels patients (Low Grade High-Grade Glioma) see if they were related to clinical outcome, MRI parameter pathological features.
 Method Between 2020-2021, pre-operative blood samples taken from 39 radiologically diagnosed who performed...

Latar belakang : Rinore liquor cerebro spinal (LCS) adalah kebocoran LCS yang terjadi karena adanya defek pada basis kranii sehingga terdapat hubungan antara intrakranial dengan cavum nasal. Sternberg’s canal merupakan kongenital di dinding lateral sphenoid. Kasus ini menjelaskan etiologi serta penatalaksanaan pasien rinore dan meningoensefalokel.
 Laporan kasus Dilaporkan wanita usia 32 tahun keluhan keluar cairan hidung kiri terkadang mengalir deras, hilang timbul selama 1 disertai...

Background: Cushing’s syndrome is condition caused by excessive glucocorticoid with insomnia as one of its neuropsychiatric manifestation. may be adrenocorticotropin hormone (ACTH-dependent), for example from ACTH producing pituitary tumors, or overproduction cortisol adrenocortical tumors. In this report, we presented a case manifesting chronic adrenal cortical adenoma and microadenoma.Case presentation: A 30-year-old woman was consulted the Neurologic Department to Internal Medicine chief...

Background: Degenerative spinal disease increases in proportion to life expectancy. Surgical treatments that play an essential role the management of degenerative have evolved from open surgery minimally invasive as well endoscopic surgery. Advanced pathological understanding, diagnostic imaging, and instrument progress support for The study aims report current situation treat diseases Department Neurosurgery Kariadi Hospital.Method: Review Endoscopy Spine Surgery case Hospital with...