A5013407142- Neurobiology and Insect Physiology Research
- Hypothalamic control of reproductive hormones
- Neuropeptides and Animal Physiology
- Physiological and biochemical adaptations
- Growth Hormone and Insulin-like Growth Factors
- Regulation of Appetite and Obesity
- Reproductive biology and impacts on aquatic species
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Receptor Mechanisms and Signaling
- Animal Behavior and Reproduction
- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Thyroid Disorders and Treatments
- Amphibian and Reptile Biology
- Antimicrobial Peptides and Activities
- Insect and Arachnid Ecology and Behavior
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Olfactory and Sensory Function Studies
- Adipose Tissue and Metabolism
- Birth, Development, and Health
- Insect and Pesticide Research
- Biochemical Analysis and Sensing Techniques
- Hormonal and reproductive studies
- Circadian rhythm and melatonin
Waseda University
2016-2025
Toho University
2009-2014
Shizuoka University
2001-2013
University of Shizuoka
2007
Japan Science and Technology Agency
2003
Hiroshima University
2002
University of California, San Francisco
1989-2002
Gunma University
1993-2001
Showa University
2001
Gunma Prefectural College of Health Sciences
2001
Ghrelin is a newly discovered peptide that released from the stomach and neurons in hypothalamic arcuate nucleus (ARC) potently stimulates growth hormone release food intake. Neuropeptide-Y (NPY) ARC play an important role stimulation of The present study aimed to determine whether ghrelin directly activates NPY and, if so, explore its signaling mechanisms. Whether respond could be regulated by orexin leptin was also examined. We isolated single rats measured cytosolic Ca2+ concentration...
A decapeptide called sodefrin was isolated from the abdominal gland of cloaca male red-bellied newt, Cynops pyrrhogaster . The native peptide, as well synthetic one, had a female-attracting activity. Sodefrin found in apical portion epithelial cells gland. is apparently species specific because it did not attract females ensicauda This first amphibian pheromone to be identified and peptide vertebrate.
We have identified the amphibian ghrelin from stomach of bullfrog. also examined growth hormone (GH)-releasing activity this novel peptide in both rat and The three forms identified, each comprised 27 or 28 amino acids, possessed 29% sequence identity to mammalian ghrelins. A unique threonine at acid position 3 (Thr(3)) bullfrog differs serine present ghrelins; Thr(3) is acylated by either n-octanoic n-decanoic acid. frog ghrelin-28 has a complete structure GLT...
Neuropeptides similar to the molluscan cardioexcitatory Phe-Met-Arg-Phe-NH 2 have been identified in several vertebrates and characterized by RFa motif at their C terminus (RFa peptides).In this study, we sought identify an amphibian hypothalamic peptide that may regulate secretion of hormones anterior pituitary gland.An acid extract bullfrog hypothalami was passed through C-18 reversed-phase cartridges, then retained material subjected HPLC, initially using a column.RFa immunoreactivity...
Antiserum to prolactin (PRL) of bullfrog (f), Rana catesbeiana, was produced by immunizing rabbits with the highly purified fPRL obtained from adenohypophyses adult bullfrogs. In Ouchterlony's agar double diffusion test, a single precipitin line between antiserum and or pituitary extract. No ovine PRL, bovine growth hormone (GH) fGH. The acetone-dried powder glands which had been incubated much less potency in promoting collagen synthesis tail fin tadpoles than that normal rabbit serum....
We previously identified in the bullfrog a novel hypothalamic RFamide peptide (SLKPAANLPLRF-NH(2)) that stimulated GH release vitro and vivo therefore was designated frog GH-releasing (fGRP). Molecular cloning of cDNA encoding deduced fGRP precursor polypeptide further revealed it encodes its related peptides (fGRP-RP-1, -RP-2, -RP-3). In this study immunoaffinity purification using antibody against conducted to determine whether these three putative fGRP-RPs exist as mature endogenous...
Sodefrin‐like female‐attracting pheromone was purified from the abdominal glands of male sword‐tailed newts, Cynops ensicauda , by gel‐filtration chromatography and reversed‐phase high‐performance liquid chromatography. The final product comprises 10 amino acid residues with sequence SILSKDAQLK which coincided deduced its precursor cDNA. This peptide designated silefrin. silefrin different that sodefrin two residues, substitutions Leu for Pro Gln at positions 3 8, respectively. Both native...
ABSTRACT A single subcutaneous injection of 4 mg monosodium glutamate (MSG) to neonatal female mice resulted in obesity when the became adult. The MSG-treated had significantly smaller contents prolactin and growth hormone (GH) pituitary, as compared with controls at 60, 150 420 days age except for content 60 age. development normal pre-neoplastic mammary systems was markedly suppressed oestrous cycles showed longed periods oestrus shorter dioestrus than those controls. pituitary weight...