A5085727687- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Photoreceptor and optogenetics research
- Porphyrin and Phthalocyanine Chemistry
- Photochemistry and Electron Transfer Studies
- Supramolecular Chemistry and Complexes
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Molecular Junctions and Nanostructures
- Radical Photochemical Reactions
- Chemical Synthesis and Analysis
- Lanthanide and Transition Metal Complexes
- Multimedia Communication and Technology
- Synthetic Organic Chemistry Methods
- Supramolecular Self-Assembly in Materials
- Organic Chemistry Cycloaddition Reactions
- Photochromic and Fluorescence Chemistry
- Photosynthetic Processes and Mechanisms
- Click Chemistry and Applications
- Chemical Thermodynamics and Molecular Structure
- Neuroscience and Neural Engineering
- Molecular spectroscopy and chirality
- Spectroscopy and Laser Applications
Queen's University Belfast
2015-2025
University of Colombo
2023
BTG International (United Kingdom)
2015-2020
Queen's University
1993-2020
Nara Women's University
2003-2004
Abstract Currently available approaches to molecular‐scale logic gates are summarized and compared. These include: chemically‐controlled fluorescent transmittance‐based switches concerned with small molecules, DNA oligonucleotides fluorescence readout, oligonucleotide reactions DNA‐based catalysts, chemically‐gated photochromics, reversibly denaturable proteins, molecular machines optical electronic signals, two‐photon fluorophores multichromophoric transient switches. The photochemical...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTIntegration of Logic Functions and Sequential Operation Gates at the Molecular-ScaleA. Prasanna de Silva, Isabelle M. Dixon, H. Q. Nimal Gunaratne, Thorfinnur Gunnlaugsson, Pamela R. S. Maxwell, Terence E. RiceView Author Information School Chemistry, Queen's University Belfast BT9 5AG, Northern Ireland Cite this: J. Am. Chem. Soc. 1999, 121, 6, 1393–1394Publication Date (Web):January 28, 1999Publication History Received13 August...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTMolecular Photoionic AND Logic Gates with Bright Fluorescence and "Off−On" Digital ActionA. Prasanna de Silva, H. Q. Nimal Gunaratne, Colin P. McCoyView Author Information School of Chemistry, Queen's University Belfast BT9 5AG, Northern Ireland Cite this: J. Am. Chem. Soc. 1997, 119, 33, 7891–7892Publication Date (Web):August 20, 1997Publication History Received17 April 1997Published online20 August inissue 1...
Poly(N-isopropylacrylamide) in aqueous solution undergoes a phase transition at approximately 32 degrees C. The fluorescence properties of benzofurazans are affected by solvent polarity. We combine these two characteristics for the first time to develop sensitive fluorescent molecular thermometers. Five monomers having benzofurazan skeleton were synthesized, and copolymers N-isopropylacrylamide (NIPAM) small quantity monomer obtained investigate their properties. With increase temperature,...
Abstract Chemists are now able to emulate the ideas and instruments of mathematics computer science with molecules. The integration molecular logic gates into small arrays has been a growth area during last few years. design principles underlying collection these cases examined. Some computing molecules applicable in medical‐ biotechnologies. Cases blood diagnostics, ‘lab‐on‐a‐molecule’ systems, computational identification objects included.
Constructs of fluorophores, receptors, spacers, <sup>1</sup>O<sub>2</sub> sensitizers, enzymes and oligonucleotides play their part in advancing the field molecular logic-based computation.
This short review illustrates how the wealth of receptors and ligands available within coordination/supramolecular chemistry can serve as a launch-pad for producing information-handling optical-based molecular devices various kinds: sensors, assay reagents, logic gates even small-scale number processors. Such diverse range information-handlers allows addressing problems in different areas from common viewpoint. The viewpoint is strengthened further when we find that design principles are...
The green luminescence of the terbium complex 1 is increased by a factor 16 when amino groups in side chains are protonated. Because its has lifetime 0.62 ms, this can serve as an effective pH sensor intrinsically fluorescent environments.
Luminescent molecular thermometers are new-generation analytical tools. These consist of species and inform us temperature by means light signals that can be detected with high sensitivity. Therefore, luminescent have a great advantage in measuring the tiny spaces. In this article, reviewed terms their mechanisms features.
The importance of the modular structure 'fluor-spacer-amine 'is pointed out for design fluorescent molecular sensors pH according to principle photoinduced electron transfer (PET). Anthracen-9-yl methylamines (24) and some azacrown ether analogues (15 23) are examined in this context. They show pH-dependent fluorescence quantum yields describable by eqn. (5) while all other electronic spectral parameters remain essentially pH-invariant. range pKa values these understandable terms macrocyclic...
Fluorescent molecular thermometers based on polymers showing a temperature-induced phase transition and labeled with polarity-sensitive fluorescent benzofurazans are the most sensitive known. Here we show simple effective method for modulating temperature ranges of such temperature-responsive polymers. 4-N-(2-Acryloyloxyethyl)-N-methylamino-7-N,N-dimethylaminosulfonyl-2,1,3-benzoxadiazole was adopted as benzofurazan, nine copolymers two kinds acrylamide derivative (N-n-propylacrylamide,...
Hi-fi mapping: Multiplexing fluorescent sensors that simultaneously target proton concentration and polarity move to micellar nanospaces, self-regulate their positions, report pKa values wavelengths, which are controlled by local environments. Such sensory functions enable maps of gradients near membranes be drawn.
The use of a water-soluble, thermo-responsive polymer as highly sensitive fluorescence-lifetime probe microfluidic temperature is demonstrated. fluorescence lifetime poly(N-isopropylacrylamide) labelled with benzofurazan fluorophore shown to have steep dependence on around the phase transition and photophysical origin this response established. unusual fluorescent in conjunction imaging microscopy (FLIM) enables spatial variation device be mapped, micron scale, resolution less than 0.1 °C....
Abstract Molecular-logic based computation (MLBC) has grown by accumulating many examples of combinational logic gates and a few sequential variants. In spite inspirations being available in biology, there are virtually no MLBC chemistry where operations integrated. Here we report simple alcohol-ketone redox interconversion which switches macrocycle between large or small cavity, with erect aromatic walls create deep hydrophobic space collapsed respectively. Small guests can be captured...
Molecular logic-based computation for a variety of uses is occurring in over thousand laboratories worldwide, where supramolecular associations are key.
Sensor 1 signals the simultaneous presence of sodium and phosphate with an increased fluorescence signal in manner a photoionic AND logic gate.