ACANTHOCYTOSIS has been characterized as a genetic disorder manifested by the appearance of spiny red cells in peripheral blood smear, abnormal lipid metabolism usually involving absent β-lipoproteins, steatorrhea, retinitis pigmentosa, and alterations central nervous systems including atrophy certain muscle groups.¹In 1966 complete review this was published Farquhar Ways.² In 1960 Levine et al³gave preliminary report patient family presented paper. The...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSIMPLIFICATION OF THE GATTERMANN SYNTHESIS HYDROXY ALDEHYDESRoger Adams and I. LevineCite this: J. Am. Chem. Soc. 1923, 45, 10, 2373–2377Publication Date (Print):October 1, 1923Publication History Published online1 May 2002Published inissue 1 October 1923https://pubs.acs.org/doi/10.1021/ja01663a020https://doi.org/10.1021/ja01663a020research-articleACS PublicationsRequest reuse permissionsArticle Views1180Altmetric-Citations61LEARN ABOUT THESE...

MIGRAINE has been defined as an affection characterized by paroxysmal attacks in which a distinctive type of headache, usually unilateral, is the most constant feature, commonly accompanied nausea and vomiting. This condition more common females occurs preponderatingly neurotic families. The immediate exciting cause attack individuals who are predisposed to it any undue fatigue or excitement nervous system. These patients very often show symptoms suggestive either irritation paralysis...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of olefin and aromatic hydrocarbonsW. F. Faragher, J. C. Morrell, I. M. LevineCite this: Ind. Eng. Chem. Anal. Ed. 1930, 2, 1, 18–24Publication Date (Print):January 1930Publication History Published online1 May 2002Published inissue 1 January 1930https://pubs.acs.org/doi/10.1021/ac50069a008https://doi.org/10.1021/ac50069a008research-articleACS PublicationsRequest reuse permissionsArticle Views88Altmetric-Citations7LEARN ABOUT THESE...

Abstract Background In patients with inflammatory bowel disease (IBD), multimorbidity obesity and type 2 diabetes is common increasing. Glucagon-like peptide 1 (GLP-1) receptor agonists are increasingly being prescribed for IBD, yet their impact on IBD largely unknown. We aimed to assess the of GLP-1 course IBD. Methods identified all at a large academic healthcare network between 2009 2023. analyzed demographics characteristics in year pre- post–GLP-1 agonist prescription matched them...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of olefins by bromine titrationJ. C. Morrell and I. M. LevineCite this: Ind. Eng. Chem. Anal. Ed. 1932, 4, 3, 319–321Publication Date (Print):July 1, 1932Publication History Published online1 May 2002Published inissue 1 July 1932https://doi.org/10.1021/ac50079a035RIGHTS & PERMISSIONSArticle Views188Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008...

Abstract Background Capsule endoscopy (CE) provides a novel approach to evaluate obscure gastrointestinal bleeding. Yet CE is not routinely utilized in the inpatient setting for variety of reasons. We sought identify factors that predict complete and diagnostically meaningful CE, as well assess impact on further hospital management.1 na d2 Methods conducted retrospective review patients undergoing at tertiary referral, academic center over 3 year period. analyzed data patient demographics,...

Telephone telemetry of bioelectric signals was developed primarily as a physiological monitoring device for patients unable to come the medical electronic laboratory. In addition, it provides patient and physician with immediate diagnostic consultation facilities interpretation data without regard distance. Any signal may at this time be telemetered. Multiplexing devices, now under development, will facilitate simultaneous multiple signals.

Sacroiliitis is an inflammatory arthritis of the sacroiliac joints and associated with bowel disease (IBD). Yet, sacroiliitis often goes undiagnosed in IBD, clinical association between IBD activity not well established. Patients Crohn's (CD) receive magnetic resonance enterography (MRE) to assess activity, affording clinicians opportunity evaluate for presence sacroiliitis. We aimed identify prevalence characteristics CD patients undergoing MRE.All MRE any indication 2014 2018 at referral...

IN THE military veteran population, excessive sweating of the palms and soles is not an uncommon complaint. Of one thousand consecutive dermatological patients with service-connected skin disorders, 30 were found to have hyperhidrosis hands and/or feet, 21 had dishidrosis. These cases all carefully diagnosed selected by eliminating fungus pyogenic infections, sensitization dermatitis, eczematoid eruptions. According Hopkins his associates,¹symmetrical lividities described as...

In preclinical studies, 5‐imino‐2,2,4,4‐tetrakis (trifluoromethyl) imidazolidine (EXP 338) revealed potential muscle relaxant action at nontoxic levels in experimental animals. Our evaluation was carried out on 15 spastic multiple sclerosis patients. Eotablished methods of inducing spasticity and recording skeletal hypertonia quantitatively extracting integrated electromyogram data were used. Five patients tested directly the polygraph laboratory 10 home via telephone telemetry...

A procedure for direct recording of the electromyogram in polygraph laboratory, integration raw data, and distant monitoring EMG is presented graphic form. telephone telemetry system known as telmedography or telemedography, especially useful obtaining ECG EEG data from nonambulatory patients their homes, also described. The accompanying figures serve to illustrate equipment involved laboratory recording, its uses bedridden with neurospastic disorders, obiective obtained.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTApproximate determination of olefin and aromatic hydrocarbonsJ. C. Morrell I. M. LevineCite this: Ind. Eng. Chem. Anal. Ed. 1932, 4, 3, 321–322Publication Date (Print):July 1, 1932Publication History Published online1 May 2002Published inissue 1 July 1932https://pubs.acs.org/doi/10.1021/ac50079a036https://doi.org/10.1021/ac50079a036research-articleACS PublicationsRequest reuse permissionsArticle Views31Altmetric-Citations2LEARN ABOUT THESE...

Ustekinumab is used to treat autoimmune inflammatory diseases including psoriatic arthritis and Crohn's disease. Hematologic side effects have not been previously described. We present a patient who developed thrombocytopenia after starting ustekinumab. report 38 year old male with Treatment history included 6-mercaptopurine (discontinued due neutropenia), adalimumab infliximab (both discontinued loss of response anti-drug antibodies). Thus, ustekinumab was initiated. At initiation, the...