A5059985491- Neurobiology of Language and Bilingualism
- Transcranial Magnetic Stimulation Studies
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Heart Rate Variability and Autonomic Control
- Dementia and Cognitive Impairment Research
- Functional Brain Connectivity Studies
- Spatial Neglect and Hemispheric Dysfunction
- Cardiovascular and exercise physiology
- Heart Failure Treatment and Management
- Non-Invasive Vital Sign Monitoring
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
- Language Development and Disorders
- Cognitive Functions and Memory
- Epilepsy research and treatment
- Cardiovascular Syncope and Autonomic Disorders
- Action Observation and Synchronization
- ECG Monitoring and Analysis
- Text Readability and Simplification
- Pharmacological Effects and Toxicity Studies
- Cystic Fibrosis Research Advances
- Frailty in Older Adults
- Protein Degradation and Inhibitors
Istituti di Ricovero e Cura a Carattere Scientifico
2005-2025
Centro San Giovanni di Dio Fatebenefratelli
2017-2025
University of Brescia
2003-2021
Vita-Salute San Raffaele University
2017-2018
Fondazione Salvatore Maugeri
2005-2007
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2006
Istituti Clinici Scientifici Maugeri
2003-2005
Paced breathing (PB) around 0.25 Hz has been advocated as a means to avoid confounding and standardize measurements in short-term investigations of autonomic cardiovascular regulation. Controversy remains, however, whether it causes any alteration control. We addressed this issue 40 supine, middle-aged, healthy volunteers by assessing the changes induced PB (0.25 for 8 min) on 1) ventilatory parameters, 2) indexes control function, 3) spectral variability. Subjects were grouped into group 1...
In recent years, the potential usefulness of cognitive training procedures in normal aging and mild impairment (MCI) have received increased attention.The main aim this study was to evaluate efficacy face-to-face virtual reality rehabilitation system (VRRS) compare it that treatment as usual for individuals with MCI. Moreover, we assessed possibility prolonging effects a telerehabilitation system.A total 49 subjects MCI were assigned 1 3 groups randomized controlled trial design: (a) those...
Parkinson's Disease (PD) with mild cognitive impairment (MCI) (PD-MCI) represents one of the most dreaded complications for patients PD and is associated a higher risk developing dementia. Although transcranial direct current stimulation (tDCS) has been demonstrated to improve motor non-motor symptoms in PD, date, no study investigated effects tDCS on Theory Mind (ToM), i.e., ability understand predict other people's behaviours, PD-MCI.In this randomized, double-blind, sham-controlled study,...
Episodic memory is impaired in amnestic mild cognitive impairment (aMCI), which posited as a potential prodromal form of Alzheimer's disease. Reactivated existing memories become sensitive to modification during reconsolidation. There evidence that the lateral prefrontal cortex (PFC) plays causal role episodic Transcranial direct current stimulation (tDCS) applied PFC after contextual reminder enhanced performance up 1 month, conceivably through reconsolidation, older adults with subjective...
The default mode (DMN) and the salience (SN) networks show functional hypo-connectivity in Alzheimer's disease (AD) behavioral variant of frontotemporal dementia (bvFTD), respectively, along with patterns hyper-connectivity. We tested clinical neurobiological effects noninvasive stimulation over these 45 patients (AD bvFTD) who received either anodal (target network: DMN AD, SN or cathodal bvFTD). evaluated changes clinical, cognitive, structural connectivity, perfusion measures. In both...
Abstract Background: Hereditary hemochromatosis is a recessive disorder characterized by iron accumulation in parenchymal cells, followed organ damage and failure. The mainly attributable to the C282Y H63D mutations HFE gene, but additional HFE, transferrin receptor 2 (TfR2), hepcidin genes have been reported. copresence of different may explain phenotypic heterogeneity its variable penetrance. Methods: We used denaturing HPLC (DHPLC) for rapid DNA scanning (exons 2, 3, 4), hepcidin, TfR2 4...
Episodic memory is critical to daily life functioning. This type of declarative declines with age and the earliest cognitive function be compromised in Alzheimer's disease (AD). Subjective complaints are commonly reported by older adults have been considered a risk factor for developing AD. The possibilities prevention disorders increased substantially recent years. Previous studies shown that anodal transcranial Direct Current Stimulation (tDCS) applied over left lateral prefrontal cortex...
Abstract Episodic memory shows the largest degree of age-related decline. Anodal transcranial Direct Current Stimulation (tDCS) can enhance episodic in aging but there is also evidence response variability even when using identical stimulation parameters. To explore which inter-individual factors (i.e. age, education, encoding performance, cognitive reserve, tDCS group and timing application) may directly and/or indirectly modulate verbal recall, we used data from our previous studies that...
Background: Healthy cognitive functioning is a primary component of well-being, independence, and successful aging. Cognitive deficits can arise from various conditions, such as brain injury, mental illness, neurological disorders. Rehabilitation highly specialized service limited to patients who have access institutional settings. In response this unmet need, telehealth solutions are ideal for triggering the migration care clinics patients’ homes. Objectives: The aim EARLY-COGN^3 will be...
Abstract Aging is accompanied by changes in cognitive abilities and a great interest spreading among researchers about aging impact on social cognition skills, such as the Theory of Mind (ToM). Transcranial direct current stimulation (tDCS) has been used studies founding evidence sex-related different effects ToM task young people sample. In this randomized, double-blind, sham-controlled study, we applied one active sham tDCS session medial prefrontal cortex (mPFC) during task, including...
<b><i>Background:</i></b> We evaluated the psychometric proprieties of Screening for Aphasia in NeuroDegeneration (SAND) battery Italian primary progressive aphasia (PPA) and movement disorder (MD) patients. <b><i>Methods:</i></b> The sample included 30 consecutive PPA 45 MD patients who completed SAND together with a clinical interview neurological/neuropsychological examination 130 healthy controls (HC)....
The observation of neurological patients showing selective impairments for specific conceptual categories contributed in the development semantic memory theories. Here, we studied two (P01, P02), affected, respectively, by variant Primary Progressive Aphasia (sv-PPA) and Cortico-Basal Syndrome (CBS). An implicit lexical decision task, including concrete (animals, tools) abstract (emotions, social, quantity) concepts, was administered to healthy controls.P01 P02 showed an abolished priming...
Background In recent years, an increasing number of studies have examined the potential efficacy cognitive training procedures in individuals with normal ageing and mild impairment (MCI). Objective The aims this study were to (i) evaluate Virtual Reality Rehabilitation System (VRRS) combined anodal transcranial direct current stimulation (tDCS) applied left dorsolateral prefrontal cortex compared placebo tDCS VRRS (ii) determine how prolong beneficial effects treatment. A total 109 subjects...
Transcranial Direct Current Stimulation (tDCS) has become an increasingly promising tool for understanding the relationship between brain and behavior. The purpose of this study was to investigate whether magnitude sex- age-related tDCS effects previously found in medial prefrontal cortex (mPFC) during a Theory Mind (ToM) task correlates with social cognition performance; particular, we explored different patterns activity would be detected high- low-performing participants. For this, young...
Memory impairment is among one of the greatest cognitive complaints in midlife and old age. Considering importance good memory functioning everyday life, it crucial to study interventions that can reduce natural decline this function. Transcranial Magnetic Stimulation (TMS) studies have demonstrated lateral prefrontal cortex (PFC) plays a causal role enhancing episodic recall through reconsolidation. Using similar paradigm with transcranial direct current stimulation (tDCS) over left PFC,...