A5101444965- Myasthenia Gravis and Thymoma
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac electrophysiology and arrhythmias
- Tracheal and airway disorders
- Complement system in diseases
- Gastrointestinal disorders and treatments
- Pituitary Gland Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Ion channel regulation and function
- Venous Thromboembolism Diagnosis and Management
- Lymphoma Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Hemoglobinopathies and Related Disorders
- Traditional and Medicinal Uses of Annonaceae
- Pancreatic and Hepatic Oncology Research
- Cardiac Arrest and Resuscitation
- Adenosine and Purinergic Signaling
- Ultrasound in Clinical Applications
- Adrenal and Paraganglionic Tumors
- Polyomavirus and related diseases
- Schizophrenia research and treatment
- Nosocomial Infections in ICU
- Ion Transport and Channel Regulation
- ECG Monitoring and Analysis
Kentucky State University
2024
Healthwise
2022
Creighton University
2021
Interfaith Medical Center
2014-2020
St. John's Riverside Hospital
2018
Carilion Clinic
2018
American College of Chest Physicians
2017
Pokhara University
2013
Background Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common chronic condition. Approximately 70% of type 2 diabetes mellitus (T2DM) patients have a liver; progression to non-alcoholic steatohepatitis (NASH) dramatically increases risks cirrhosis and hepatocellular carcinoma. The aim our study was assess profile enzymes in subjects with T2DM NAFLD. Method This cross-sectional clinic-based T2DM. An ultrasonography abdomen done all order examine presence liver. Body mass...
BackgroundPatients with obstructive sleep apnea-hypopnea syndrome (OSAHS) present a variety of sleep-related symptoms. In polysomnography, architecture is almost always abnormal, but it not known which the sleep-stage abnormalities are related to Finding key abnormality that cause symptoms may be therapeutic importance alleviate So far mainstay treatment continuous positive airway pressure (CPAP)/bi-level (BIPAP) therapy, many patients non-compliant it. Correcting by pharmacotherapy become...
Background: Drug utilization research has been defined by the WHO as .the marketing, distribution, prescription and use of drugs in a society, with special emphasis on resulting medical, social economic consequences. Several studies drug conducted many developed countries shows wide evidence irrational use. Objectives: To assess pattern Primary Health Care (PHC) facilities Kaski district, Western Nepal. Methods :A prospective cross-sectional descriptive study was 11 PHC district using core...
Foreign body aspiration (FBA) is more common in children than adults with about 80% occurring aged less 15 years. FBA often overlooked as a potential cause of airway obstruction especially if there no asphyxiation. We present case 45-year-old male alcohol abuse who presented post-obstructive pneumonia secondary to tooth unknown duration. The was removed via flexible bronchoscopy (FBr) and we will discuss the use FBr for foreign (FB) removal, which FB can be easily by FBr, different...
Clozapine is the preferred antipsychotic used for treatment of resistant schizophrenia with suicidal ideation. The drug started at a low dose and gradually increased to target 300-450 mg/day. It well known cause agranulocytosis neutropenia. Several cases fatal sepsis have been reported in neutropenic patients emphasis placed on monitoring agranulocytosis; however, clozapine also causes intestinal hypomotility constipation, which if unrecognized can lead obstruction, bowel necrosis,...
Brugada syndrome is an inherited arrhythmogenic disease, characterised by a coved-type ST segment elevation in right precordial leads and increased risk of sudden cardiac death due to ventricular arrhythmia. To unmask or exacerbate ECG pattern, class IA IC antiarrhythmic agents are used, clinicians can predict high-risk patient. However, phenytoin, one the IB agents, may induce pattern at supra-therapeutic level this association has rarely been reported. We describe case patient with...
With the rising incidence of hepatocellular carcinoma (HCC), ongoing efforts should be focused on providing equitable and state-of-the-art care to patients.The aim this study was determine survival patients with HCC seen at a high-proportion Safety Net Hospital (h-SNH), where loco-regional therapy hepatology services are available liver transplantation (LT) is referred outside facilities.A retrospective cohort conducted all Valley Wise Health Center (VWHC) over ten-year period. Clinical...
Objective: We present a rare case of pernicious anemia presented as multi-organ dysfunction syndrome, later found to have pseudo-thrombotic thrombocytopenic purpura. Methods: An 86-year-old female with respiratory distress, altered mental status, acute renal failure and was intubated in emergency room. She severe anemia, thrombocytopenia, high lactate, lactate dehydrogenase low haptoglobin. Peripheral smear revealed multilobulated neutrophils schistocytes, poikilocytes anisocytes. Results:...
Background Contrast-induced nephropathy (CIN) is one of the leading causes morbidity and mortality including increased financial burden in high risk patients undergoing percutaneous coronary intervention (PCI). Methods This an observational prospective study. We aimed to study incidence CIN Nepalese populations compare outcome international reprinted values with artery disease (CAD) PCI. All consecutive CAD PCI between February 2010 July were enrolled Results One hundred fifty-two during six...
Introduction . Acquired thrombotic thrombocytopenic purpura (TTP) has been associated with different autoimmune disorders. However, its association pernicious anemia is rarely reported. Case Report A 46-year-old male presented blood in sputum and urine for one day. The vitals were stable. physical examination was significant icterus. Lab tests’ results revealed leukocytosis, macrocytic anemia, severe thrombocytopenia, renal dysfunction, unconjugated hyperbilirubinemia. He had an elevated...
Association of thymoma with myasthenia gravis, pure red cell aplasia, and aplastic anemia is well documented. However, complicated by acquired amegakaryocytic thrombocytopenia (AAMT) rarely reported. Here, we present a case 60-year-old male past medical history recurrent invasive who presented cough blood in sputum. He was found to have severe normocytic normochromic that did not improve intravenous steroids or multiple transfusions cells platelets. Subsequent bone marrow biopsy showed...
Objective: Our study aimed to determine the national estimates of 30-day all-cause readmission rate among patients with spontaneous pneumothorax and investigate burden these readmissions in terms mortality, length stay hospitalization costs USA. Methods: We utilized Nationwide Readmission Database for 2013-2014 identified adults a primary diagnosis pneumothorax. analyzed reported patient- hospital-level variables cohort. outcome was rate, including reasons readmission. secondary outcomes...
Introduction: The aim of our study is to determine the clinical, biochemical, and imaging factors that affect duration hospital stay in patients admitted with normotensive acute pulmonary embolism. Methods: This was a single-center retrospective conducted community New York metropolitan area for from October 2015 2017. Results: A total 79 were included, mean age 55.76 (SD = 17.33), 29 cases males (37%) 50 females (63%). Among all patients, 17 had short length (LOS) (≤2 days) 62 long LOS (>2...
An isolated descending colonic stricture is an unlikely complication of acute pancreatitis, with the nonspecific symptoms making overall diagnosis difficult. Crohn’s disease (CD) and tuberculosis (TB) are two common etiologies may present similarly to related pancreatitis. Unfortunately, colonoscopy biopsy often cannot determine etiology, surgical resection be needed provide both symptomatic relief confirm diagnosis. As a result, produce diagnostic dilemma CD TB as all 3 conditions...
Dronedarone is a class III antiarrhythmic agent and potent blocker of multiple intracardiac ion channels with many electrophysical properties common amiodarone. Oral dronedarone, 400 mg twice daily, approved for the maintenance normal sinus rhythm in patients history atrial fibrillation (AF) or flutter. It primarily used paroxysmal persistent AF relatively new therapeutic which non-iodinated congener amiodarone hypothesized to have far lesser side effects. Photosensitivity an uncommon effect...
Sarcoidosis is a granulomatous disease of unknown etiology which may present with systemic manifestations. The diagnosis gastric sarcoidosis needs much effort to accomplish as it exceedingly rare, and the treatment usually recommended exclusively for symptomatic disease. Here, we case in 31-year old black female patient symptoms nausea epigastric pain. A was mainly based on presence non-necrotizing granulomas biopsy following esophagogastroduodenoscopy (EGD). She treated steroid high dose at...
Abstract Non-small cell lung cancer (NSCLC) is a primary type of and leading cause cancer-related mortality worldwide. The Warburg effect, characterized by increased glycolysis reduced oxidative phosphorylation, hallmark NSCLC presents therapeutic target. Annonacin, natural compound found in fruits from the Annonaceae family, interferes with phosphorylation inhibiting mitochondrial complex I. 2-deoxy-d-glucose (2DG), glucose analog, disrupts glycolysis. This study examines effects Annonacin...
Objectives: Lymphoplasmacytic lymphoma (LPL) is a mature B cell that usually involves the bone marrow, spleen and lymph nodes. Extramedullary involvement, including lung, rarely reported. Case description: A 73-year-old female initially presented to our hospital complaining of productive cough white-colour sputum for three weeks duration. She reported unintentional weight loss ten pounds over last five months. There was no history haemoptysis, fever, night sweats, chills, recent infections...
Lyme disease is a multisystem infection caused by the spirochete Borrelia burgdorferi sensu stricto that manifests with characteristic symptoms in patients. Patients are identified based on their clinical and then diagnosed through enzyme-linked immunosorbent assay (ELISA), Western blot, blood culture techniques. Here, we present case of 75-year-old, Northeast suburban resident complaining unstable gait, high fevers, malaise, myalgia, confusion. This patient’s were nonspecific, his lab...