A5022289907- Pharmaceutical Practices and Patient Outcomes
- Pain Management and Opioid Use
- Medication Adherence and Compliance
- Pharmacological Effects and Toxicity Studies
- Pharmacy and Medical Practices
- Pharmacovigilance and Adverse Drug Reactions
- Pharmacogenetics and Drug Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Drug Transport and Resistance Mechanisms
- Palliative Care and End-of-Life Issues
- Opioid Use Disorder Treatment
- Delphi Technique in Research
- Artificial Intelligence in Healthcare and Education
- Lung Cancer Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Intramuscular injections and effects
- Schizophrenia research and treatment
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Cancer survivorship and care
- Clinical practice guidelines implementation
- Chemotherapy-induced cardiotoxicity and mitigation
- Drug-Induced Hepatotoxicity and Protection
- Pharmaceutical Economics and Policy
- Blood Pressure and Hypertension Studies
Xiangya Hospital Central South University
2021-2025
Central South University
2021-2025
Wuhan University of Science and Technology
2023-2025
Dali University
2021-2023
Zhejiang Normal University
2023
National Clinical Research
2023
Patients with chronic conditions need multiple medications daily to manage their condition. However, most patients have poor compliance, which affects the effectiveness of treatment. To address these challenges, we establish a medication reminder system for intelligent generation universal schedule (UMS) remind diseases take accurately and improve safety home medication.
Background With the climbing incidence of type 2 diabetes, health care system is under pressure to manage patients with this condition properly. Particularly, pharmacological therapy constitutes most fundamental means controlling blood glucose levels and preventing progression complications. However, its effectiveness often hindered by factors such as treatment complexity, polypharmacy, poor patient adherence. As new technologies, artificial intelligence digital technologies are covering all...
Self-management of ambulatory cancer pain is full challenges. Motivated by the need for better management, we developed a WeChat-supported platform, Medication Housekeeper (MediHK), to enhance communication, optimize outcomes, and promote self-management in home setting.We conducted randomized controlled trial assess whether joint physician-pharmacist team through MediHK would provide patients with pain.Patients were randomly assigned either an intervention group or control group. During...
In China, pharmacists have started to manage cancer pain at outpatient clinics. This retrospective study performed a tertiary teaching hospital was aimed evaluate the effects of physician-pharmacist joint clinic for management. The between December 2016 and August 2019 included 113 outpatients with moderate severe cancer-related pain. Patients were divided into two groups according each patient visited: (joint group, n = 59) or physician-only (usual 54). Brief Pain Inventory (BPI) Morisky...
Background: There exists no broad agreement of experts on the practice pharmaceutical care for cancer pain management in outpatient clinics. Objectives: This study aimed to use Delphi consensus process provide expert recommendations clinics from point view clinical and future trials. Methods: A comprehensive literature review was conducted draft initial practice. In this process, 30-40 senior various provinces China were invited rank items during two consultations. The definitions included a...
Central nervous system adverse events (AEs) occur when oxycodone is used in combination with benzodiazepines, antidepressants and anticonvulsants. There have been no reports of central AEs alone or oxycodone. Based on USA Food Drug Administration Adverse Event Reporting System (FAERS) data, this study aims to explore the risk signals anticonvulsants, provide a reference for safe rational use drug.
1. Breviscapine was an active ingredient of flavonoid glycosides. Our present study conducted to evaluate the impact breviscapine on pharmacokinetics losartan and its metabolite E-3174, that relationship with gene polymorphism CYP2C9 in healthy Chinese volunteers, provide a basis for clinical rational drug use.2. The genotypes 217 subjects were determined using PCR-RFLP. Twelve selected known (six CYP2C9*1/*3 six CYP2C9*1/*1) two-phase randomised crossover design study. These given daily...
Objective: To examine whether joint management of cancer pain by physicians and pharmacists in clinics provides economic advantages from the perspective Chinese healthcare system. Methods: From February 2018 to March 2020, 100 patients who visited clinic at Xiangya Hospital Central South University were included. These randomly assigned either control or intervention groups. The group received regular outpatient services a physician, while physician medication education provided pharmacist....
To explore OTC (over-the-counter drugs) in Chinese community pharmacies often causes ADE (adverse drug event) elderly patients.
The use of anticholinergic drugs in the elderly may lead to negative events such as falls, delirium, urinary retention and cognitive decline, higher number use, more occur. This study aims analyze risk factors associated with prescription total outpatients evaluate rationality drugs, provide a reference for reducing adverse effects drugs.
Background: Breviscapine is a flavonoid extracted from Erigeron breviscapus (Vant.) Hand.-Mazz., and mainly contains scutellarin. Nuclear receptors play important roles in regulating transporter drug metabolic enzymes. Objective: To investigate the regulatory effects of scutellarin on CYP3A4 2C19 HepG2 Caco-2 cells based nuclear PXR CAR. Methods: The proteins mRNA levels CYP2C19 treated with were detected by Western Blot RT-qPCR. Using assays dual-luciferase reporter, promoter sequences...
In late 2019, coronavirus disease (COVID-19) began to spread globally and is highly contagious. Due its exceptionally rapid high mortality rate, it not yet possible be eradicated. order halt the of COVID-19, there a pressing need for effective screening infected patients immediate medical intervention. The absence accurate methods identify has led model early diagnosis with suspected having COVID-19 reduce probability missed misdiagnosis. Modern automatic image recognition techniques are an...
<sec> <title>BACKGROUND</title> Self-management of ambulatory cancer pain is full challenges. Motivated by the need for better management, we developed a WeChat-supported platform, Medication Housekeeper (MediHK), to enhance communication, optimize outcomes, and promote self-management in home setting. </sec> <title>OBJECTIVE</title> We conducted randomized controlled trial assess whether joint physician-pharmacist team through MediHK would provide patients with pain. <title>METHODS</title>...
Abstract Objective Comparing the characteristics of end-of-dose failure patients and non-end-of-dose in Chinese population exploring factors that may affect occurrence cancer pain patients. Methods The outpatient with from 2016 to 2019 were collected through hospital information system, included who met following criteria: average numerical rating scale ≥4 points within 3 days after taking oxycodone sustained-release preparation, titrated an effective therapeutic dose suitable for patients,...
<sec> <title>BACKGROUND</title> Self-management of ambulatory cancer pain is full challenges. Motivated by the need for better management, we developed a WeChat-supported platform, Medication Housekeeper (MediHK), to enhance communication, optimize outcomes, and promote self-management in home setting. </sec> <title>OBJECTIVE</title> We conducted randomized controlled trial assess whether joint physician-pharmacist team through MediHK would provide patients with pain. <title>METHODS</title>...