- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Physical Activity and Health
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Cardiovascular and exercise physiology
- Metabolomics and Mass Spectrometry Studies
- RNA regulation and disease
- Nutrition and Health in Aging
- Ginkgo biloba and Cashew Applications
- Renin-Angiotensin System Studies
- Biological and pharmacological studies of plants
- Ginseng Biological Effects and Applications
- Autophagy in Disease and Therapy
- Hormonal Regulation and Hypertension
- Free Radicals and Antioxidants
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Analysis
- Cancer, Hypoxia, and Metabolism
- Coronary Interventions and Diagnostics
- Gastroesophageal reflux and treatments
- Cardiac Valve Diseases and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
First Affiliated Hospital of Zhengzhou University
2014-2024
Zhengzhou People's Hospital
2016
Huazhong University of Science and Technology
2007
Abstract Aims This multicentre observational study aimed to prospectively assess the efficacy of left bundle branch area pacing (LBBAP) in heart failure patients with block (LBBB) and compare 6‐month outcomes between LBBAP biventricular (BVP). Methods results Consecutive LBBB ventricular ejection fraction (LVEF) ≤ 35% were recruited if they had undergone as a primary or rescue strategy from three separate centres March December 2018. Patients who received BVP 2018 retrospectively selected by...
BACKGROUND:The objective of this study was to investigate the molecular mechanism atrial fibrillation (AF), as well negative regulatory relationship between miR-29a-3p and CACNA1C. MATERIAL AND METHODS:We searched online miRNA database (www.mirdb.org) identified binding sequence within 3'-UTR target gene, then conducted luciferase assay verify it. The cells were transfected with ICa,L determined in those cells. RESULTS:We validated CACNA1C be direct gene miR-29a-3p. We also established via...
The aim of the present study was to investigate cardioprotective effect tanshinone IIA and underlying molecular mechanisms. An in vitro model oxidative stress injury established cardiac H9c2 cells, effects IIa were investigated using cell viability, reverse transcription-quantitative polymerase chain reaction western blotting assays. results demonstrated that protects cells from H2O2-induced death a concentration-dependent manner, via mechanism involving microRNA-133 (miR-133), treatment...
Abstract Background Cryoballoon ablation (CBA) and radiofrequency (RFA) are the most common procedures used to treat refractory atrial fibrillation (AF) performed through pulmonary vein isolation (PVI). Studies have shown that CBA can approximately match therapeutic effects of RFA against AF. However, few studies investigated difference between on left remodeling for paroxysmal Objective Atrial is considered pivotal occurrence development AF, therefore we sought assess influence in patients...
Abstract BACKGROUND The non-exercise estimated cardiorespiratory fitness (eCRF) has been recognized as an important predictor of mortality among the general population. This study sought to evaluate relationship between eCRF and from all causes, cardiovascular disease (CVD), cancer in hypertensive adults. METHODS We included 27,437 adults with hypertension National Health Nutrition Examination Survey (NHANES) III 10 NHANES cycles 1999 2018. Multivariate Cox proportional hazard models were...
Abstract Background Stent dislodgement is a rare but particularly challenging complication. However, current treatment strategies are suboptimal. Objective This study sought to preliminarily assess the feasibility of novel self-expanding basket (SEB) catheter successfully retrieve dislodged stent during percutaneous coronary intervention (PCI). Method The SEB designed as tip made superelastic shape nitinol memory alloy, which could automatically expand tightly wrap and flatten deformed...
Atrial fibrillation (AF) is the most common cardiac arrhythmia. High mobility group box 1 (HMGB1) has been demonstrated to be involved in AF, but genetic relationship between them not clear yet. Here, we investigated association functional variants HMGB1 and AF a Chinese Han population.Two (the promoter one rs1045411T/C 3'UTR rs1412125C/T) were selected genotyped 576 patients 869 control subjects. Traditional risk factors, such as age, gender, history of smoking, hypertension diabetes...