Hidenori Une

ORCID: 0009-0000-2600-1624
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Research Areas
  • Oral health in cancer treatment
  • Platelet Disorders and Treatments
  • Head and Neck Cancer Studies
  • Cell Adhesion Molecules Research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Salivary Gland Disorders and Functions
  • Magnesium in Health and Disease
  • Air Quality and Health Impacts
  • Hedgehog Signaling Pathway Studies
  • Oral and gingival health research
  • Cancer Diagnosis and Treatment

Chugoku Central Hospital
2018-2023

Oral microbiota may be associated with serious local or systemic medical conditions resulting from chemotherapy. This study was conducted to evaluate the changes in oral following initiation of chemotherapy patients hematopoietic malignancies and identify characteristics mucositis. samples were collected 57 at 2 time points: before start 8 20 days after chemotherapy, when chemotherapy-induced mucositis often occurs, 16S rRNA metagenomic analyses performed. Comparative linear discriminant...

10.1177/15347354231159309 article EN cc-by-nc Integrative Cancer Therapies 2023-01-01

CD81, a transmembrane protein belonging to the tetraspanin family, has recently attracted attention as therapeutic target for cancer owing its important role in human biology; however, there is no previous knowledge regarding CD81 expression parotid cancer. Therefore, this study aimed investigate and involvement cell proliferation. Tissue samples were collected from 36 patients with cancer, including 10 salivary duct carcinoma (SDC), 16 mucoepidermoid (MEC), five adenoid cystic (ACC), ex...

10.1016/j.ajoms.2023.08.012 article EN cc-by-nc-nd Journal of Oral and Maxillofacial Surgery Medicine and Pathology 2023-08-18

Cetuximab is a molecular targeting drug used to treat various malignant tumors. Although patients with head and neck cancer treated cetuximab had longer survival, notable adverse effects were frequently observed as compared who received chemotherapy cytotoxic drugs. In this study, we investigated cetuximab-induced hypomagnesemia in oral cancer. From February 2013 through May 2017, 33 combination or radiotherapy studied. Among the patients, 17 (51.5%) presented symptoms of 3 (9.1%) Grade 3/4...

10.5794/jjoms.64.634 article EN Japanese Journal of Oral & Maxillofacial Surgery 2018-11-20

Abstract Objectives CD81, a transmembrane protein belonging to the tetraspanin family, has recently attracted attention as therapeutic target for cancer owing its important role in human biology; however, there is no previous knowledge regarding CD81 expression parotid cancer. Therefore, this study aimed investigate and involvement cell proliferation. Materials Methods Tissue samples were collected from 36 patients with cancer, including 10 salivary duct carcinoma (SDC), 16 mucoepidermoid...

10.21203/rs.3.rs-3037775/v1 preprint EN cc-by Research Square (Research Square) 2023-06-15

Abstract Background Recently, the gut microbiota has been shown to play an important role in response and resistance chemotherapy. Although there is much knowledge about chemotherapy-induced changes microbiota, chemotherapy-associated oral remain unclear. Herein, we aimed evaluate associated with initiation of chemotherapy patients malignant hematopoietic tumors. Methods Oral samples were collected before 8–20 days after start from 50 tumors who starting for first time. The 16S ribosomal RNA...

10.21203/rs.3.rs-854887/v1 preprint EN cc-by Research Square (Research Square) 2021-08-31
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