A5041692298- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- Plant and animal studies
- Chronic Disease Management Strategies
- Genetic diversity and population structure
- Bariatric Surgery and Outcomes
- Diabetes Treatment and Management
- interferon and immune responses
- Global Health Care Issues
- Medication Adherence and Compliance
- SARS-CoV-2 and COVID-19 Research
- Bipolar Disorder and Treatment
- Genetic Associations and Epidemiology
- Medical Coding and Health Information
- Pharmaceutical studies and practices
- COVID-19 Clinical Research Studies
University of Helsinki
2023-2025
Human Technopole
2024-2025
Politecnico di Milano
2024-2025
Institute for Molecular Medicine Finland
2023-2025
Finland University
2023-2024
Abstract Obesity is a major public health challenge. Glucagon-like peptide-1 receptor agonists (GLP1-RA) and bariatric surgery (BS) are effective weight loss interventions; however, the genetic factors influencing treatment response remain largely unexplored. Moreover, most previous studies have focused on race ethnicity rather than ancestry. Here we analyzed 10,960 individuals from 9 multiancestry biobank across 6 countries to assess impact of known loss. Between 12 months, GLP1-RA users...
Low drug adherence is a major obstacle to the benefits of pharmacotherapies and it therefore important identify factors associated with discontinuing or being poorly adherent prescribed treatment regimen. Using high-quality nationwide health registry data genome-wide genotyping, we evaluate impact socio-demographic genetic risk on persistence for 5 common medication classes that require long-term, regular therapy (N = 1,814,591 individuals from Finnish registries, 217,005 Finland Estonia)....
Separate populations at the edge of a species range are receiving great attention and have been shown to be often different from in core area. However, it has rarely tested whether neighboring peripheral genetically evolutionarily similar each other, as expected for their geographical proximity ecological conditions, or differ due historical contingency. We investigated isolation differentiation, within-population genetic diversity evolutionary relationships among multiple cold-adapted...
Abstract Background In Italy, regional governments maintain data warehouses of linked administrative health (AHD) to demographic information including mortality. Legal reporting pathways for death certificate detail bypass the Region, resulting in significant amounts missing on cause and location AHD limiting epidemiological research mortality incidence. this study, we determine first time Italy degree agreement between last hospital diagnosis primary death, how that changes over time....