A5034998258- Congenital Heart Disease Studies
- Zebrafish Biomedical Research Applications
- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Vibrio bacteria research studies
- Congenital heart defects research
Max Planck Institute for Heart and Lung Research
2024
German Centre for Cardiovascular Research
2024
Haverford College
2008
Cardiac contractions and hemodynamic forces are essential for organ development homeostasis. Control over cardiac can be achieved pharmacologically or optogenetically. However, these approaches lack specificity require direct access to the heart. Here, we compare two genetic control by modulating levels of sarcomeric protein Tnnt2a in zebrafish. We first recombine a newly generated tnnt2a floxed allele using multiple lines expressing Cre under cardiomyocyte-specific promoters, show that it...
Viruses that infect phytoplankton are abundant in all regions of the global ocean. Despite their ubiquity, little is understood regarding how biotic interactions can alter virus infection success as well fate hosts. In previous work, bacterially derived compound 2-heptyl-4-quinolone (HHQ) has been shown to protect cosmopolitan coccolithophore Emiliania huxleyi from virus-induced mortality. The present study explores potential mechanisms through which protection conferred. Using a suite...