ABSTRACT Astrocytes are crucial for central nervous system (CNS) development and function, with their differentiation being stringently controlled by epigenetic mechanisms, such as histone modifications. Enhancer of Zeste Homologue 2 (EZH2), a methyltransferase, is essential the suppression gene expression. However, role EZH2 in astrocyte early morphogenesis has remained unclear. Using an astrocyte‐specific Ezh2 knockout (cKO) mouse model, we examined effects deletion on morphogenesis,...

The purpose of this study was to examine the effect environmental performance on subjective well-being against background different levels economic development in China. findings from CGSS2015, combined with quality data using multi-level linear regression analysis method, indicated that public’s satisfaction will significantly enhance their happiness. GDP variable found moderate reference expectation theory, positing people have high expectations happiness provinces a GDP. higher being...

Academic studies on environmental pollution have convincingly acknowledged the salient relevance of ambient pollutant emissions individual life satisfaction. However, an understanding how different dimensions air influence public self-assessment their living condition is required. This research investigates whether objective and subjective evaluation The findings were based data from China Environment Yearbook Social Survey in 2019. multi-level linear regression model found that pollutants...

Bacteroides fragilis (B. fragilis), a crucial commensal bacterium within the gut, has shown connections with hepatic lipid metabolism and inflammation regulation. Nonetheless, role of B. in progression fatty liver hemorrhagic syndrome (FLHS) remains unknown. This study aims to explore ameliorative effects on FLHS laying hens, as well its underlying mechanisms. is first employ chicken model, combining microbiomics oxylipin metabolomics investigate mechanism action intestinal symbiotic...

Though many scholars and practitioners are paying more attention to the health life of public after COVID-19 outbreak, extant literature has so far failed explore variation ambient air quality during this pandemic. The current study attempts fill gap by disentangling causal effects epidemic prevention on in China, measured individual pollutant dimensionless index, from other confounding factors. Using fixed model, article finds that five indicators, PM2.5, PM10, CO, NO2, SO2, significantly...

Purpose The paper examines how local governments’ responses to citizens’ complaints about environment issues are affected when the involve conflicting goals, particularly economic versus environmental goals. This study focuses on responsiveness of provincial governments citizen Local Leader Message Board (LLMB) in China. Design/methodology/approach collected 125,364 environment-related lodged by citizens LLMB from 2013 2021 and identified embodying goals through a Structural Topic Model...

<title>Abstract</title> Objective Social participation is a determinant of active aging and has significant impact on the health middle-aged elderly. This study aims to analyses social level equity among elderly in China, examines moderating role services utilization. Methods Data are extracted from 2018 China Health Retirement Longitudinal Study (CHARLS), which nationally representative survey for people aged 45 years more. The Orderly Logistic model used empirically analyze inequality,...

The revival and development of values education in the world has become a hot topic field new century. With increasing demands government people from all walks life on education, research begun to increase international academic circles. This paper tries adopt method knowledge mapping, select literature “values education” SSCI database 2009 2018 as analysis object, use CiteSpace software analyze education. finds that number publications is year by year, forming core focused pedagogy,...

The artificial fluorinated group of compounds polyfluoroalkyl chemicals (PFCs) has been applied extensively in daily life for decades, and is present food, drinking water, indoor dust. nephrotoxicity PFCs widely studied its characteristics being mainly excreted through passing urine affecting urodynamics. This work aimed to investigate the relationship between occurrence urge urinary incontinence (UUI) United States (US) population.There were 3157 eligible female participants retrieved from...

Good political skills can help subordinates disguise their ingratiation as organizational citizenship behavior.Few studies has told us what measures should be taken when the managers can't tell difference between behavior and ingratiation.In this paper, survey data were collected at two different time points from 338 subordinate 128 supervisors 6 electronic manufacturing enterprises located in Beijing, china.The conclusion of paper is that leaders make sure trust themselves they such kind or...

To better study managers' contextual ambidextrous abilities, this research investigates the relationship between network consistency and ambidexterity based on complex adaptive system theory in dynamic environment.The is tested by using primary survey data from organizational members.The author collected 108 at level.Through hierarchical regression analyses, conclusion that formal informal emotional first low then increase abilities a U-shaped relationship.Theoretical contributions empirical...

Objective According to analyse SCI papers published by hospital faculties during the period of 2010-2015, this paper discussed influential factors and strategies for publishing from perspective scientific research management, proposed suggestions administrative department leaderships decision-making. Methods Taking database developed Institute Scientific Information (ISI) as data resource. Literature analysis method was used analyze 2010-2015 in terms amount, subject development ,...

Plural leadership is an important development trend of the group mode. At present, a large quantity literature has conducted theoretical and empirical research on plural leadership, among which, most key concern effectiveness leadership. From early exploration relationship between two variables to introduction mediating mechanisms moderator that influence strength or direction this relationship, academics have in-depth studies. However, there are still different views around current For...