A5024009972- HIV-related health complications and treatments
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Vaccine Coverage and Hesitancy
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Child and Adolescent Health
- Healthcare Systems and Challenges
- Respiratory viral infections research
University of Liverpool
2023-2024
Health Protection Research Unit in Emerging and Zoonotic Infections at University of Liverpool
2023-2024
Newcastle University
2017-2021
Abstract Objective To quantify changes in inequalities uptake of childhood vaccination during a period steadily declining overall rates England. Design Longitudinal study. Setting General practice data for five vaccines administered to children (first and second doses the measles, mumps, rubella vaccine (MMR1 MMR2, respectively), rotavirus vaccine, pneumococcal conjugate (PCV) booster, six-in-one (DTaP/IPV/Hib/HepB) covering diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type...
Validated screening tools for HIV-associated neurocognitive disorders (HAND) are lacking the newly emergent ageing population of people living with HIV (PLWH) in sub-Saharan Africa (SSA). We aimed to validate and compare diagnostic accuracy two cognitive tools, International dementia scale (IHDS), Identification Interventions Dementia Elderly Africans (IDEA) screen, identification HAND older PLWH Tanzania. A systematic sample 253 aged ≥ 50 attending a Government clinic Tanzania were screened...
HIV-associated neurocognitive disorders (HANDs) are prevalent in older people living with HIV (PLWH) worldwide. HAND prevalence and incidence studies of the newly emergent population combination antiretroviral therapy (cART)-treated PLWH sub-Saharan Africa currently lacking. We aimed to estimate using robust measures stable, cART-treated adults under long-term follow-up Tanzania report cognitive comorbidities.Longitudinal study.A systematic sample consenting HIV-positive aged ≥50 years...
HIV-associated neurocognitive disorder (HAND), although prevalent, remains a poorly researched cause of morbidity particularly in sub-Saharan Africa (SSA). We aimed to explore the risk factors for HAND people aged 50 and over under regular follow-up at government HIV clinic Tanzania.HIV-positive adults years were approached recruitment routine appointment 4-month period. A diagnostic assessment was implemented, including full medical/neurological collateral history from relative....
Abstract In the UK, incidence and prevalence of inflammatory bowel disease (IBD) is increasing in paediatric populations. Environmental factors including acute gastroenteritis episodes (AGE) may impact IBD development. Infant rotavirus vaccination has been shown to significantly reduce AGE. This study aims explore association between with live oral vaccines A population-based cohort was used, analysing primary care data from Clinical Practice Research Datalink Aurum. Participants included...
<h3>Objective</h3> HIV infection is a major cause of disease burden and disability across sub-Saharan Africa (SSA). HIV-associated neurocognitive impairment (HAND) estimated to affect 8 million people with the continent associated increased mortality morbidity. As result demographic transition coverage combination antiretroviral therapy (cART) proportion aged 50 over living in SSA predicted triple (to 9 by 2040). Despite this, few published data exist on prevalence of, or risk factors for,...
Abstract Objective This study aims to quantify changes in inequalities childhood vaccination uptake the context of steadily declining overall rates England. Design Cross-sectional longitudinal study. Setting We analysed general practice (GP) level data for five vaccinations (MMR1, MMR2, rotavirus, pneumococcal (PCV) booster and six-in-one vaccine) from Cover Vaccination Uptake Evaluated Rapidly dataset Participants Children under 5 years age eligible paediatric immunisations between April...