A5113264447- Genetics, Bioinformatics, and Biomedical Research
- Effects and risks of endocrine disrupting chemicals
- Enzyme Production and Characterization
- Per- and polyfluoroalkyl substances research
- Advanced Proteomics Techniques and Applications
- Toxic Organic Pollutants Impact
Anhui University
2024
Per- and polyfluoroalkyl substances (PFAS) are widely used persistent synthetic chemicals that have been linked to adverse health effects. While the behavior of PFAS has evaluated in environment, our understanding reaction products mammalian systems is limited. This study identified biological transformation generated mass spectral libraries facilitate an automated search identification. The 27 PFAS, spanning 5 chemical subclasses (alcohols, sulfonamides, carboxylic acids, ethers, esters),...
Natural enzymes are often difficult to meet the needs of application and research in terms activity, enantiomer selectivity or thermal stability. Therefore, it is an important task enzyme engineering explore efficient molecular modification technologies improve properties such enzymes. The mainly include rational design, directed evolution, artificial intelligence-assisted design. Directed evolution design experiment-driven approaches have been successfully applied engineering. However, due...