A5007729735- Cancer-related molecular mechanisms research
- Plant Stress Responses and Tolerance
- Plant Genetic and Mutation Studies
- Plant Parasitism and Resistance
- Cancer-related gene regulation
- Substance Abuse Treatment and Outcomes
- MicroRNA in disease regulation
- Behavioral Health and Interventions
- Circular RNAs in diseases
- Alcohol Consumption and Health Effects
- RNA modifications and cancer
Lanzhou University
2024
Army Medical University
2018-2024
Southwest Hospital
2018-2024
Increasing evidence shows microRNAs (miRNAs) are engaged in hepatocelluar carcinoma (HCC). To identify novel feasible miRNA/mRNA pairs involved hepatocarcinogenesis, an in-depth analysis of miRNomes human non-tumor liver and HCC samples was carried out this study. Firstly, differentially expressed miRNAs were obtained from deep sequencing 15 samples, verified independent data The Cancer Genome Atlas (TCGA) database. Then, mRNA targets selected TCGA, the differential with negative...
Lespedeza potaninii, a xerophytic subshrub belonging to the legume family, is native Tengger Desert and highly adapted drought. It has important ecological value due its drought adaptability, but underlying molecular mechanisms remain largely unknown. Here, we report 1.24 Gb chromosome-scale assembly of L. potaninii genome (contig N50 = 15.75 Mb). Our results indicate that underwent an allopolyploid event with 2 subgenomes, A B, presenting asymmetric evolution B subgenome dominance. We...