A5101188317- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Bladder and Urothelial Cancer Treatments
- Neutropenia and Cancer Infections
- Colorectal and Anal Carcinomas
- Pancreatic and Hepatic Oncology Research
- Immunotherapy and Immune Responses
- Colorectal Cancer Treatments and Studies
- Immune Cell Function and Interaction
- Urinary and Genital Oncology Studies
- Lymphoma Diagnosis and Treatment
- Opioid Use Disorder Treatment
- Growth and nutrition in plants
- Workplace Violence and Bullying
- Plant Micronutrient Interactions and Effects
- Musculoskeletal pain and rehabilitation
- Blood Pressure and Hypertension Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Brain Metastases and Treatment
- Cassava research and cyanide
- Melanoma and MAPK Pathways
- Gut microbiota and health
Universidad de las Fuerzas Armadas ESPE
2025
Hospital Universitario Ramón y Cajal
2024
Instituto Ramón y Cajal de Investigación Sanitaria
2024
Instituto Cajal
2022-2024
Tufts University
2022
Previous studies have suggested a negative impact of steroids on the efficacy immune checkpoint inhibitors (ICI), but how this effect is modulated by dosage and time administration yet to be clarified. We performed retrospective analysis 475 patients with advanced solid tumors treated ICI as monotherapy from 2015 2022. Data regarding immune-related adverse events (irAEs) clinical outcomes were collected. For each patient, daily steroid dose (in mg/kg prednisone) was registered until disease...
Abstract Background Immune checkpoint inhibitors (ICI) have changed the therapeutic landscape of many solid tumors. Modulation intestinal microbiota by antibiotics (Abx) has been suggested to impact on ICI outcomes. Methods Retrospective analysis 475 patients with advanced tumors treated from 2015 2022. For each patient, use Abx was recorded 1 month before initiation until disease progression or death. The objective response rates (ORR), control (DCR), progression-free survival (PFS), and...
El adecuado manejo nutricional es crucial para el desarrollo y producción de cannabinoides en cultivo Cannabis sativa var. Cherry Oregon. Esta investigación tuvo por objetivo evaluar efecto cinco concentraciones solución nutritiva Steiner la fenología del cáñamo medicinal, determinar dosis óptima contenido (cannabidiol [CBD] tetrahidrocannabinol [THC]). La fue realizada Instituto Nacional Investigaciones Agropecuarias [INIAP], Estación Experimental Santa Catalina [EESC], Ecuador, condiciones...
Abstract Previous studies have suggested a negative impact of steroids on the efficacy immune checkpoint inhibitors (ICI), but how this effect is modulated by dosage and time administration yet to be clarified. We performed retrospective analysis 475 patients with advanced solid tumors treated ICI as monotherapy from 2015 2022. Data regarding immune-related adverse events (irAEs) clinical outcomes were collected. For each patient, daily steroid dose (in mg/kg prednisone) was registered until...
12083 Background: The detrimental impact of steroids (ST) on patients receiving immune checkpoint inhibitors (ICI) has been described in several studies. However, the influence indication, time administration, and dosage is more controversial. Methods: This a retrospective analysis 475 with advanced solid tumors treated ICI at tertiary university hospital, between 2015 2022. Data related to baseline characteristics clinical outcomes were collected. For each patient, daily ST dose (equivalent...