A5101549365- Gut microbiota and health
- Atrial Fibrillation Management and Outcomes
- Gastrointestinal motility and disorders
- Meta-analysis and systematic reviews
- Cardiac Arrhythmias and Treatments
- Metallurgical Processes and Thermodynamics
- Iron and Steelmaking Processes
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Mycorrhizal Fungi and Plant Interactions
- Traditional Chinese Medicine Studies
- Acute Ischemic Stroke Management
- Circular RNAs in diseases
- Metal Extraction and Bioleaching
- Cancer-related molecular mechanisms research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Advanced Battery Materials and Technologies
- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Nematode management and characterization studies
- Advanced Fiber Laser Technologies
- Antiplatelet Therapy and Cardiovascular Diseases
- MicroRNA in disease regulation
University of Alberta
2024-2025
Fujian Medical University
2018-2025
Second Affiliated Hospital of Fujian Medical University
2018-2025
Shanghai Institute of Optics and Fine Mechanics
2025
Third Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Shaoxing University
2019-2024
Harbin Institute of Technology
2024
Xidian University
2024
Liaoning Provincial People's Hospital
2024
Abstract Background The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was identified as overexpressed HCC cases through bioinformatics analysis. This study aimed to investigate the oncogenic properties and mechanisms circPIAS1 development. Methods Functional analyses were conducted assess circPIAS1’s impact on cell proliferation, migration, ferroptosis. Xenograft mouse models employed evaluate effects tumor growth...
Trace elements play a critical role in the pathogenesis of autism spectrum disorders (ASD). The aim this study was to investigate serum levels zinc (Zn) and copper (Cu) Chinese children with ASD. Sixty patients (48 males, 12 females) diagnosed ASD 60 healthy sex-matched age-matched control participants were assessed for Zn Cu content at admission. severity also evaluated using Childhood Autism Rating Scale (CARS) score. results indicated that mean Zn/Cu ratio significantly lower compared...
Functional constipation (FC) is a gastrointestinal disorder with high incidence, and it seriously affects patients' physical mental health. Several studies have shown that the gut microbiome associated FC, but these produced inconsistent findings, few reflecting relationship between metabolites. This study used 16S rRNA microbial genomics non-target metabolome based on liquid chromatography-mass spectrometry to analyze microbiota composition serum metabolic profiles of 30 FC patients 28...
Constipation is a major health concern worldwide, requiring effective and safe treatment options. This study mainly focused on three species nine strains of bifidobacteria from different sources to their abilities relieve constipation induced by loperamide in BALB/C mice. By monitoring constipation-related indicators, it was found that only Bifidobacterium longum (B. longum) relieved constipation, which indicated had inter-species differences relieving constipation. Furthermore, through the...
The occurrence of non-alcoholic fatty liver disease (NAFLD) is closely related to intestinal microbiota disturbance, and probiotics has become a new strategy assist in alleviating NAFLD. In order investigate the effect Bifidobacterium on NAFLD possible pathway, model was established by using high-fat diet (HFD) for 18 weeks. Fourteen strains were selected (seven adolescentis seven bifidum) intervention. effects different bifidobacteria evaluated from cell injury, fat deposition, inflammatory...
Constipation is a major health concern worldwide and requires effective safe treatment options. In this study, we selected ten strains of two species lactobacilli to identify whether they were against constipation induced by loperamide administration in BALB/c mice. Monitoring constipation-related indicators indicated that Lactobacillus paracasei (L. paracasei) mainly acted on the whole intestinal peristalsis relieve constipation. Furthermore, through detection biological, chemical,...
Controversies exist concerning the association between serum lipids and ischemic stroke. To investigate relationship lipid, apolipoprotein E (apoE) genotype risk of We measured concentrations lipids, lipoprotein (a) [Lp(a)], apoE genotype, as well distribution other potential factors, in 90 pairs age- sex-matched stroke patients stroke-free controls. The prevalence hypertension, family history smoking drinking habits were significantly higher cases than Total cholesterol, low-density Lp(a)...
Cathartic colon (CC), a type of slow-transit constipation caused by the long-term use stimulant laxatives, does not have precise and effective treatment. This study aimed to evaluate ability Bifidobacterium bifidum CCFM1163 relieve CC investigate its underlying mechanism. Male C57BL/6J mice were treated with senna extract for 8 weeks, followed 2-week treatment B. CCFM1163. The results revealed that effectively alleviated symptoms. possible mechanism in relieving was analyzed measuring...
Bifidobacterium animalis subsp. lactis pretreatment coordinately regulates colonic and serum metabolites, influencing the systemic immune responses of neonatal rats to Salmonella infection.
Uncontrolled lithium (Li) dendrite formation presents major safety risks and challenges in the Li host design. A novel approach is introduced, using a valence gradient iron nanoparticles (Fe0, Fe2+, Fe3+) to stabilize anodes. An Fe0 component, with fast diffusion, ensures steady supply of Fe2+ Fe3+ components, which have slower diffusion. This coordinated interplay between slow diffusion uniformizes deposition near substrate, effectively reducing rate growth. The as-prepared framework...
We present a novel, to the best of our knowledge, fiber-optic radio frequency (RF) phase synchronization scheme utilizing division multiplexing, eliminating need for time reference. The method begins by generating two homologous RF signals with an integer multiple relationship. These are then modulated onto same laser carrier through intensity modulation. A detector 2π rad range is used measure variations in lower signal induced fiber link. An optical delay line compensates fiber-induced...
Immunoglobulin A (IgA), as the most secreted immunoglobulin in intestine, plays an irreplaceable role mucosal immunity regulation. Previous studies have indicated that Lactobacillus showed strain specificity stimulating secretion of IgA through intestinal lymphocytes. The reason for this phenomenon is not clear. current been aimed at exploring effect a on host's but mechanism behind it has seriously studied. Based this, we selected five strains fermentum isolated from different individuals...