J.-H. Chen

ORCID: 0009-0003-0464-2035
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Viral-associated cancers and disorders
  • SARS-CoV-2 and COVID-19 Research
  • Molecular Biology Techniques and Applications
  • RNA Research and Splicing
  • Viral Infections and Outbreaks Research
  • Ferroptosis and cancer prognosis
  • Blood disorders and treatments
  • Neutropenia and Cancer Infections
  • Cancer, Lipids, and Metabolism
  • Cardiovascular Disease and Adiposity
  • Influenza Virus Research Studies
  • Oral health in cancer treatment
  • Lymphoma Diagnosis and Treatment
  • Heat shock proteins research

Guangzhou Medical University
2015-2024

University of Macau
2024

Evive Biotech (China)
2024

Guangzhou First People's Hospital
2015

Abstract The identification of ferroptosis‐sensitive cancers is critical for the application ferroptosis‐inducing therapies in cancer therapy. Here, patient‐derived organoid screening models colorectal are established to identify tumors that sensitive This study discovers characterized by mitophagy deficiency hypersensitive therapies. Mechanistically, a novel negative feedback regulatory pathway lipid peroxidation identified, which one important intrinsic anti‐ferroptosis mechanisms cells....

10.1002/advs.202412593 article EN cc-by Advanced Science 2024-12-16

This study aimed to evaluate the immunogenicity non-inferiority and safety of quadrivalent inactivated split-virion influenza vaccine in participants ≥ 3 years old. A total 3,328 were enrolled. Participants 3-8 old administered one or two doses investigational dose control vaccine, whereas other only vaccine. The occurrence adverse events (AEs) after 30 days full-course vaccination serious (SAEs) within 6 months assessed. sero-conversion rates (SCRs) anti-H1N1, H3N2, B(Y), B(V) antibodies...

10.1080/21645515.2023.2245721 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2023-08-01
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