A5054157148- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Shoulder Injury and Treatment
- Inflammatory Bowel Disease
- Neuroendocrine Tumor Research Advances
- Microscopic Colitis
- Nerve Injury and Rehabilitation
- Neuroblastoma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Intramuscular injections and effects
- Vascular Procedures and Complications
- Clostridium difficile and Clostridium perfringens research
- Celiac Disease Research and Management
- Lung Cancer Research Studies
- Pregnancy and Medication Impact
- Dupuytren's Contracture and Treatments
- Congenital limb and hand anomalies
- Orthopaedic implants and arthroplasty
- Pain Mechanisms and Treatments
- Cancer Immunotherapy and Biomarkers
- Musculoskeletal synovial abnormalities and treatments
- Gut microbiota and health
- Ultrasound in Clinical Applications
- Bone fractures and treatments
Guy's and St Thomas' NHS Foundation Trust
2025
King's College Hospital
2021-2023
King's College London
2023
King's College Hospital NHS Foundation Trust
2017-2018
Imperial College London
2015-2016
University of Oxford
2014
Science Oxford
2014
Abstract Background Faecal microbiota transplant (FMT) is an effective treatment strategy for recurrent Clostridioides difficile infection (rCDI)1, but its role in ulcerative colitis (UC), another disease involving gut dysbiosis, less certain2. Methods Patients with active UC at St Thomas’ hospital, London were given FMT according to patient preference and MDT decision. Local approval was granted the new procedure process May 2018. 200ml (80g stool 0.9% saline 12.5% glycerol) deposited...
The purpose of this study was to compare the initial and final outcome range motion in MCP-J PIP-J single digit Dupuytren's Contracture treated with either open surgical excision or manipulation after collagenase clostridium histolyticum (CCH; Xiapex) injection.Ten patients group. measurements were statistically compared using student t-test a p-value 0.05. There no statistical difference pre-treatment status total active movement (TAM) between two groups.Open release achieved better...
Sequential drug treatment with biological agents in ulcerative colitis (UC) is becoming increasingly complex. There are few studies comparing head-to-head outcomes second-line treatments. The study assesses whether using anti-tumour necrosis factor (anti-TNF)-α therapy following the α4β7 integrin blocker vedolizumab (VDZ) or VDZ after an anti-TNF has more favourable clinical UC a real-world outpatient setting.Patients who were exposed to first-line (adalimumab infliximab) subsequently...
Shoulder pain is very common in diabetic patients and often treated with steroid injections, subsequent increases blood glucose levels or the need for additional insulin being questioned. We report a case of significant prolonged elevation resultant requirement type 1 man after single 40 mg injection triamcinolone shoulder pain. Within 48 h, as assessed by visual analogue scale (0–10) was reduced to zero, but elevated requirements continued 4 weeks injection. This finding suggests that...
We present the case of a 75-year-old woman with haemochromatosis who developed 5-year-long right ulnar non-union after shortening osteotomy to correct malunited Colles’ fracture. Standard surgical treatment for non-unions was attempted on 19 March 2008 and again 20 April 2009, but persisted 8 May 2012, as confirmed by CT scan. Vascular bone grafting refixation then considered, patient declined this extensive operation, instead choosing try non-invasive low-intensity pulsed ultrasound an...
Pancreatic metastases (PMs) from neuroendocrine neoplasms (NENs) are rare but the increased sensitivity of new diagnostic tools such as 68 Ga-DOTATATE PET/CT has resulted in their recognition at initial diagnosis or follow-up. A retrospective analysis data patients six tertiary referral centres was performed order to identify characteristics and prognostic significance PMs with NENs. We used a control group 69 age-, sex- primary tumour - matched NEN same cohort stage IV disease no PMs....
We present the case of a 47-year-old man who developed non-union left radius following an open double barrel fracture to forearm sustained in road traffic accident.Whilst initially treated with internal fixation, only ulna united.The patient then underwent two failed radial revision surgeries exchange plate and simple bone grafting.A third attempt rescue was made vascularised graft, using composite fibula/skin free flap.However, within one week vascular anastomosis failed, whole flap, except...
Carpal tunnel syndrome is the most common peripheral neuropathy presenting to specialist hand and wrist clinics. Surgical decompression of carpal considered if non-surgical options have failed. outcomes may be impaired damage nerve extensive. Despite conflicting evidence, there mounting evidence that surgical for are worse in more elderly populations. Indeed, it was found 50% patients with bilateral aged over 60 completely absent sensory conduction. More extensive older patient groups due...
Thoracic outlet syndrome presents a diagnostic and management challenge to general practitioners, physicians surgeons alike. It is classified into three categories depending on the specific structure believed be impinged at thoracic (vein, artery or nerve), all of which involve pain in upper extremity. The principles generally stepwise escalation from conservative measures such as physiotherapy, activity posture modulations addition analgesic medications before surgical decompression...
Abstract Background Drug choice and order in Inflammatory Bowel Disease (IBD) is an important challenge becoming increasingly complex. There are few studies comparing head-to-head outcomes second line treatments Ulcerative Colitis (UC). It unclear if using anti-Tumour Necrosis Factor-a (anti-TNF) therapy following vedolizumab (VDZ) or VDZ after anti-TNF has a more favourable outcome UC real-world outpatient setting. Methods Patients with who were exposed to first-line (adalimumab/ADA...
<h3>Introduction</h3> Persistent villous atrophy (VA) occurs in up to 66% (Lebwohl et al 2013) following a diagnosis of coeliac disease (CD) despite gluten free diet. Refractory (RCD) affects 0.3-4% all patients with CD (Baggus 2019) and manifests persistent or recurrent classic malabsorptive symptoms weight loss diarrhoea. RCD is subclassified by intra-epithelial lymphocyte (IEL) immunophenotyping T-cell receptor (TCR) clonality into RCD1 RCD2. RCD2 carries high rate progression...