A5012937615- Mesenchymal stem cell research
- Biomedical Ethics and Regulation
- Heme Oxygenase-1 and Carbon Monoxide
- Venous Thromboembolism Diagnosis and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Nitric Oxide and Endothelin Effects
- Hematological disorders and diagnostics
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Estrogen and related hormone effects
- Axon Guidance and Neuronal Signaling
- Lipid metabolism and disorders
- Menopause: Health Impacts and Treatments
- Pancreatitis Pathology and Treatment
- Cancer, Hypoxia, and Metabolism
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Liver Disease Diagnosis and Treatment
- Neurogenesis and neuroplasticity mechanisms
- Hormonal and reproductive studies
- Tissue Engineering and Regenerative Medicine
- Inflammasome and immune disorders
Qinghai University
2024-2025
Qinghai University Affiliated Hospital
2025
Third Hospital of Hebei Medical University
2011
Hebei Medical University
2011
Shanghai Medical College of Fudan University
2006-2008
Abstract To elucidate whether vascular endothelial growth factor (VEGF) improves stroke‐induced striatal neurogenesis, we intraventricularly injected human VEGF 165 ‐expressive plasmid (phVEGF) mixed with liposome into adult rats after a transient middle cerebral artery occlusion (MCAO). The results showed that EGFP, reporter protein, positive cells appeared at 2 hr, further enhanced 4 reached the maximum 3 days and still remained 14 single injection. Treatment phVEGF increased angiogenesis,...
Hypoxia plays a pivotal role in modulating immune responses, especially neutrophils, which are essential components of the innate system. Hypoxia-inducible factor (HIF)-1α, key transcription hypoxic adaptation, regulates cellular metabolism and inflammatory responses. However, impact HIF-1α-dependent glycolysis on formation neutrophil extracellular traps (known as NETosis) under conditions remains unclear. We employed two established models, neutrophils isolated from human whole blood...
ABSTRACT Objective To assess the effects of human umbilical cord‐derived mesenchymal stem cells (hUC‐MSCs) on mitochondrial damage and metabolic disorders induced by acute chronic hypoxia in mouse kidneys. Method Comprehensive analyses were conducted, including histopathology, morphology analysis, biochemical assessments, transcriptomics metabolomics. Results The results revealed that hUC‐MSCs significantly improved renal integrity maintained dynamic balance under both hypoxia. This...