- Neuroblastoma Research and Treatments
- Systemic Lupus Erythematosus Research
- Cleft Lip and Palate Research
- Circadian rhythm and melatonin
- Signaling Pathways in Disease
- HIV, Drug Use, Sexual Risk
- T-cell and B-cell Immunology
- Glioma Diagnosis and Treatment
- dental development and anomalies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Air Quality and Health Impacts
- HIV/AIDS Research and Interventions
- Immune Cell Function and Interaction
- Craniofacial Disorders and Treatments
- Syphilis Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Pituitary Gland Disorders and Treatments
- Light effects on plants
- Circular RNAs in diseases
- Cardiovascular Health and Risk Factors
- Meningioma and schwannoma management
- Epigenetics and DNA Methylation
China Resources (China)
2024
Wuhan University of Science and Technology
2024
Anhui Medical University
2009-2022
First Affiliated Hospital of Anhui Medical University
2020
Anhui Provincial Hospital
2009-2019
The pineal hormone, melatonin (MLT), has been shown to have therapeutic effects in patients with gastric cancer; however, the mechanisms for anti-cancer are unknown. We investigated of on cell proliferation, apoptosis, colony formation and migration adenocarcinoma line, SGC7901, using MTT assay, Hoechst 33258 staining, flow cytometry, western blot, caspase-3 activity soft agar scratch-wound assay. Our results showed that could inhibit efficiency, it promoted apoptosis SGC7901 cells. findings...
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease, in which sunlight (especially ultraviolet B (UVB) 290–320 nm) known to induce exacerbation of disease. DNA methylation regulates gene expression, and hypomethylation associated with abnormal cell function SLE. The purpose this study was investigate the effect UVB on SLE its significance pathogenesis Forty-five patients 20 healthy controls were enrolled study, involved investigation methyltransferase 1 (DNMT1)...
Objective Distant metastasis or local recurrence is the leading cause of death in some patients with thyroid cancer (TC), a malignant tumor endocrine system. Circular RNA circ_0067934 (circ_0067934) has been reported to be connected tumorigenesis multiple tumors. However, there are few reports on role and regulatory mechanisms TC. Materials methods The expression levels circ_0067934, protein kinase C iota (PRKCI), microRNA-1304 (miR-1304), C-X-C chemokine receptor types 1 (CXCR1) were...
The 3 major subphenotypes observed in patients with nonsyndromic orofacial clefts (NSOFCs) are cleft lip only (NSCLO), palate (NSCLP), and (NSCPO). However, the genetic architecture underlying NSCPO is largely unknown. Here we performed a 2-stage genome-wide association study (GWAS) on replication analyses of selected variants other NSOFCs from Chinese Han population. We identified novel locus (15q24.3) known (1q32.2) where or near gene reached significance (2.80 × 10 −13 < P 1.72 −08 )...
The aims of this paper were to find out the status HIV and syphilis infection examine sexual behaviours between men who have sex with only (MSM/M) both women (MSM/W), as well determine correlates for among MSM/M MSM/W, respectively. Among 1693 MSM participated in study, proportions MSM/W 82.1% 17.9%, prevalences 7.0% 6.6% 11.9% 13.2%, subset, included having more partners, being receptive or insertive anal sex. living Chengdu was associated using condoms inconsistently during infection....