- Blockchain Technology Applications and Security
- Privacy-Preserving Technologies in Data
- Hearing, Cochlea, Tinnitus, Genetics
- Inflammasome and immune disorders
- Cellular transport and secretion
- Vestibular and auditory disorders
- Access Control and Trust
- Brain Tumor Detection and Classification
- Genomics and Rare Diseases
- IoT and Edge/Fog Computing
Hebei Medical University
2022-2024
Second Hospital of Hebei Medical University
2022-2024
University of South China
2022
With the continuous development of cryptocurrencies, blockchain technology has received extensive attention, and performance systems is constrained by consensus algorithms. In view problems high communication complexity complex process in PBFT algorithm, this paper An improvement scheme algorithm based on voting mechanism proposed. Before running protocol, nodes network vote to generate a set nodes, remaining are used as accounting nodes. At same time, traditional optimized. scheme, master...
In view of the phenomenon node voting not actively and gang crime in DPOS consensus mechanism, this paper proposes an improved scheme based on credit score, which comprehensively calculates score according to behavior record error rate, equity holders vote so as make witnesses elected more credible. The recommendation algorithm is introduced reduce centralization nodes. An incentive mechanism award points nodes that positively produce correct blocks, punish malicious Experimental results...
Background Hearing loss is considered one of the most common sensory nervous system defects, about 60% which are caused by genetic factors. Mutations in GSDME gene responsible for post-lingual, progressive, autosomal dominant hearing loss. This study aimed to characterize mutations and clinical features a Chinese family. Methods After evaluations, high-throughput DNA sequencing was conducted using samples from this Sanger performed verify suspected variants. A detailed genotype phenotype...
Abstract Hearing loss is considered one of the most common sensory neurological defects, with approximately 60% cases attributed to genetic factors. Human pathogenic variants in TBC1D24 gene are associated various clinical phenotypes, including dominant nonsyndromic hearing DFNA65, characterized by progressive after development language. This study provides an in-depth analysis causative and mutations a family hereditary deafness. We recruited three-generation autosomal (ADNSHL) conducted...
Due to concentrated and costless equity, the Proof-of-Stake (PoS) consensus mechanism is prone bifurcation block-out right determination concerns, which impacts blockchain system's stability. To address aforementioned issues, a new PoS based on memory presented. improve competition method of by long-term short-term memory, difficulty calculation workload proof, proof. The experimental results show that compared with mechanism, PoSaM weakens dominance equity over nodes' rights; it improves...