A5071416264- Cancer Immunotherapy and Biomarkers
- BRCA gene mutations in cancer
- Glutathione Transferases and Polymorphisms
- Ferroptosis and cancer prognosis
- Paraoxonase enzyme and polymorphisms
- Cancer, Lipids, and Metabolism
- Cancer Genomics and Diagnostics
- Estrogen and related hormone effects
- Diet, Metabolism, and Disease
China Three Gorges University
2018-2024
Tamoxifen treatment is important assistant for estrogen-receptor-positive breast cancer (BRCA) after resection. This study aimed to identify signatures predicting the prognosis of patients with BRCA tamoxifen treatment. Data gene-specific DNA methylation (DM), as well corresponding clinical data BRCA, were obtained from The Cancer Genome Atlas and followed by systematic bioinformatics analyses. After mapping these DM CPG sites onto genes, we finally 352 relapse-free survival (RFS) associated...
Breast cancer (BC) has emerged as an extremely destructive malignancy, causing significant harm to female patients and society at large. Proteomic research holds great promise for early diagnosis treatment of diseases, the integration proteomics with genomics can offer valuable assistance in diagnosis, treatment, improved prognosis BC patients. In this study, we downloaded breast protein expression data from The Cancer Genome Atlas (TCGA) combined construct a proteomic-based prognostic model...