A5077843876- Computational Drug Discovery Methods
- Microbial Natural Products and Biosynthesis
- Bioinformatics and Genomic Networks
- Rough Sets and Fuzzy Logic
- Fuzzy Logic and Control Systems
- Data Mining Algorithms and Applications
Centre National de la Recherche Scientifique
2024
Normandie Université
2024
Tunis University
2022-2024
Tunis El Manar University
2022-2024
GREYC
2023-2024
École Nationale Supérieure d'Ingénieurs de Caen
2024
Université de Caen Normandie
2024
Abstract The exploration of chemical space is a fundamental aspect chemoinformatics, particularly when one explores large compound data set to relate structures with molecular properties. In this study, we extend our previous work on visualization at the pharmacophoric level. Instead using conventional binary classification affinity (active vs inactive), introduce refined approach that categorizes compounds into four distinct classes based their activity levels: super active, very and...
Fuzzy Rule-Based Classification Systems (FRBCS) are a very popular and useful tool due to their interpretable classification models based on linguistic variables. However, high number of attributes leads an explosion the rules. In this paper, we interested in ensemble methods applied FRBCS. An regrouping method association rules called SIFRA was proposed solve problem. It determines relevant groups related that will be treated separately by FRBCSs. We propose Genetic Algorithm-based select...