Denise Lester

ORCID: 0009-0003-3074-6057
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About
Contact & Profiles
Research Areas
  • Pain Management and Treatment
  • Shoulder Injury and Treatment
  • Spine and Intervertebral Disc Pathology
  • Nerve Injury and Rehabilitation
  • Musculoskeletal pain and rehabilitation
  • Stroke Rehabilitation and Recovery
  • Muscle activation and electromyography studies
  • Pain Mechanisms and Treatments
  • Spinal Cord Injury Research
  • Medical Imaging and Analysis
  • Neuroscience and Neural Engineering
  • Transcranial Magnetic Stimulation Studies
  • Parkinson's Disease and Spinal Disorders
  • Soft Robotics and Applications
  • Peripheral Nerve Disorders
  • Health, Medicine and Society
  • Surgical Simulation and Training
  • Advanced MRI Techniques and Applications
  • Cardiac pacing and defibrillation studies
  • Anatomy and Medical Technology
  • Cancer Treatment and Pharmacology
  • Shoulder and Clavicle Injuries
  • Vagus Nerve Stimulation Research
  • Anesthesia and Pain Management

Hunter Holmes McGuire VA Medical Center
2019-2025

Virginia Commonwealth University
2022-2025

VA Central California Health Care System
2021-2025

University Health System
2022

Virginia Commonwealth University Medical Center
2020

Abstract Introduction Chronic pain and reduced function are significant problems for Military Service members Veterans following amputation. Peripheral nerve stimulation (PNS) is a promising therapy, but PNS systems have traditionally been limited by invasiveness complications. Recently, novel percutaneous system was developed to reduce the risk of complications enable delivery without surgery. Materials Methods Percutaneous evaluated determine if provides relief from residual phantom limb...

10.1093/milmed/usz114 article EN cc-by-nc Military Medicine 2019-05-21

Two persons with chronic motor complete spinal cord injury (SCI) were implanted percutaneous epidural stimulation (SCES) leads to enable control below the level (NCT04782947). Through a period of temporary followed by permanent SCES implantation, mapping was conducted primarily optimize configurations enabling volitional movement and training standing stepping as secondary outcome. In both participants, enabled voluntary increased muscle activation decreased assistance during...

10.1038/s41467-023-37845-7 article EN cc-by Nature Communications 2023-04-12

Introduction & aim: Temporary (60-day) percutaneous peripheral nerve stimulation (PNS) has demonstrated effectiveness for the treatment of chronic post-amputation pain, and this pilot study aims to evaluate feasibility temporary PNS acute pain. Patients methods: Sixteen veterans undergoing lower extremity amputation received standard medical therapy or alone. Results: The group reported greater reductions in average phantom limb residual pain daily opioid consumption, there were fewer...

10.2217/pmt-2021-0087 article EN cc-by-nc-nd Pain Management 2021-11-11

Introduction: Implanted spinal cord epidural stimulation (SCES) is an emerging neuromodulation approach that increases the excitability of central pattern generator [CPG] and enhances tonic rhythmic motor patterns after injury (SCI). We determine effects exoskeleton-assisted walking [EAW] + [ES] resistance training [RT] on volitional control as a primary outcome, well autonomic cardiovascular profile, body composition, bladder function compared to EAW delayed ES noRT in persons with...

10.3390/jcm14061829 article EN Journal of Clinical Medicine 2025-03-08

10.1016/j.neurom.2024.06.099 article EN Neuromodulation Technology at the Neural Interface 2024-10-01
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