Gabrielle Sheehan

ORCID: 0009-0003-3864-0863
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About
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Research Areas
  • Transcranial Magnetic Stimulation Studies
  • Attention Deficit Hyperactivity Disorder
  • Functional Brain Connectivity Studies
  • Electroconvulsive Therapy Studies
  • Maritime and Coastal Archaeology
  • Neural and Behavioral Psychology Studies
  • Archaeological and Historical Studies
  • Ancient Mediterranean Archaeology and History
  • Neural dynamics and brain function
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Memory and Neural Mechanisms
  • Identity, Memory, and Therapy

University of East London
2023-2025

Background Transcranial direct current stimulation (tDCS) has been proposed as a novel treatment in major depressive disorder (MDD). However, efficacy and safety of home-based tDCS have not investigated. Methods Fully remote, multisite, double-blind, placebo-controlled, randomized superiority trial MDD was conducted UK USA. Participants were adults 18 years or older, having diagnosis based on DSM-5 criteria, episode at least moderate severity, measured by score >=16 17-item Hamilton...

10.1101/2023.11.27.23299059 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-11-27

Abstract Aim To investigate neural oscillatory networks in major depressive disorder (MDD), effects of home-based transcranial direct current stimulation (tDCS) treatment, and potential predictors treatment remission. Methods In a randomised controlled trial (RCT) tDCS EEG data were acquired subset: 21 MDD participants (16 women) (mean age 36.63 ± 9.71 years) episode moderate to severe severity Hamilton Depression Rating Scale (HAMD) score 18.42 1.80). Participants either active (n=11) or...

10.1101/2024.06.10.24308593 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-06-10

Transcranial direct current stimulation (tDCS) is a potential home-based treatment for major depressive disorder (MDD). In our randomised controlled trial, fully remote, 10-week course of active tDCS showed greater clinical efficacy as compared to sham in double-blind trial (RCT). was administered at 2mA 30-minute sessions bifrontal montage with anode over the left dorsolateral prefrontal cortex (DLPFC) and cathode right DLPFC. Following blinded all participants could receive open label...

10.1101/2024.11.21.24317690 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-11-22

Abstract Background : Major depressive disorder (MDD) is associated with impairments in neuropsychological functioning. A key mechanism memory retrieval the process of inhibiting information that not relevant to specific memory, termed retrieval-induced forgetting (RIF). In MDD, attenuated RIF has been observed, which related memories are suppressed. The effect proposed be mediated by inhibitory functions, and associations rumination have observed. Whether functions verbal learning capacity...

10.21203/rs.3.rs-3553834/v1 preprint EN cc-by Research Square (Research Square) 2023-11-14
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