About
Contact & Profiles
A5071444450
Research Areas
- Andrographolide Research and Applications
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Parkinson's Disease Mechanisms and Treatments
- Inflammasome and immune disorders
- Pharmacological Effects and Toxicity Studies
- Drug Transport and Resistance Mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
- PARP inhibition in cancer therapy
- RNA and protein synthesis mechanisms
University of Bonn
2022-2024
Given the crucial role of main protease (M
10.1021/acs.jmedchem.4c00053
article
EN
Journal of Medicinal Chemistry
2024-05-16
Abstract Naturally occurring compounds represent a vast pool of pharmacologically active entities. One such is andrographolide, which endowed with many beneficial properties, including the activity against severe acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2). To initiate drug repurposing or hit optimization campaign, it imperative to unravel primary mechanism(s) antiviral action andrographolide. Here, we showed by means reporter gene assay that andrographolide exerts its...
10.1002/cmdc.202100732
article
EN
cc-by-nc-nd
ChemMedChem
2022-01-31
10.1016/j.bioorg.2023.106574
article
EN
Bioorganic Chemistry
2023-04-28
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