Bullous pemphigoid did not follow the course of Gastric Carcinoma relapse and remisson, unlike malignant acanthosis nigricans which was in alignment with paraneoplastic effect Carcinoma.

Prurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects patient's quality life. Previous reports highlighted role Ketogenic diet in triggering young female patients, however, no study reported occurrence siblings one family, unrelated to ketogenic diet. Here, we report two sisters diagnosed without undergoing

Actinomycosis is a rare, chronic, and slow-progressing bacterial infection caused by Actinomyces species. The condition's rarity, nonspecific clinical symptoms, occasional occurrence in atypical locations often lead to delays diagnosis, which are critical for initiating timely treatment preventing further complications. We report the case of an 82-year-old man who initially developed pustules on dorsum his left hand, gradually progressed over 15 years into exophytic mass. Histopathological...

ABSTRACT MAC is a rare adnexal tumor with nonspecific clinical presentation. Dermatologists should consider the diagnosis of when there solitary, longstanding lesion aberrant behavior supported by typical pathological findings sweat gland malignant changes.

Introduction: Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder is a rare (PCS-TCLPD) characterized by solitary erythematous plaque or nodule on the face, neck, upper trunk with favorable outcome. Very rarely multiple plaques masses may be seen in which precise evaluation should performed to exclude other primary lymphoma. Case presentation: Here we report case of recalcitrant small/ medium sized 55-year-old male patient who responded well Rituximab injection but had...

Granuloma annulare is a noninfectious, granulomatous skin disorder that typically presents as symmetrical, asymptomatic, annular, or arciform plaques with slightly raised edges, often found on the back of hands feet. This report highlights successful use tofacitinib in treating resistant/generalized granuloma 66-year-old male known history hepatitis B, demonstrating its potential an effective therapeutic option.

Key Clinical Message IgA pemphigus is usually treated by Dapsone. Recalcitrant cases may be Colchicine, Sulfapyridine, or Acitretin. Some patients with recurrent severe disease not respond to the aforementioned medications. Our study highlights role of TNFa inhibitor as an alternative modality in treatment recalcitrant pemphigus. Abstract a rare autoimmune blistering characterized pruritic, annular, vesiculopustular eruption. In pemphigus, there are autoantibodies targeting keratinocyte cell...

A 3-year-old boy was referred to Razi Dermatology Hospital due multiple pruritic plaques on the trunk and proximal extremities for 2 months. His parent reported multiple, self-healing, similar skin eruptions since 1 year ago. They denied any preceding pain or edema before eruptions. Physical examination revealed annular arcuate-like erythematous in posterior neck, face, trunk, back, proximal, distal lower (Figure 1A–C). The central clearing noticed some of lesions. Initial lab test complete...

Pyogenic granuloma presents clinically as a rapidly growing, friable, red papule of skin or mucosa, commonly measuring less than 10 mm with frequent bleeding due to ulceration. Angioproliferative diseases including pyogenic and cherry angioma have been reported during COVID-19 infection following vaccination.

Alopecia areata (AA) is a common chronic relapsing nonscarring alopecia. Severe forms of AA commonly manifest during childhood. Treatment challenging due to the variability disease course as well unpredictable responses treatment. There no uniform approved treatment for cure or sustained remission in children till now. Tofacitinib emerged novel drug AA, but few studies have been conducted on its safety and efficacy children. Limitation this study includes retrospective nature, small sample...

ABSTRACT Representative clinical images in this study can increase awareness regarding the similarity between benign adnexal tumor and malignant melanoma highlight importance of pathological examination.