A5090368151- Analytical chemistry methods development
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Chromatography
- Biochemical Acid Research Studies
- Electrochemical sensors and biosensors
- Coenzyme Q10 studies and effects
- Muscle metabolism and nutrition
- Pesticide Residue Analysis and Safety
- Environmental Chemistry and Analysis
- Environmental Toxicology and Ecotoxicology
Taras Shevchenko National University of Kyiv
2021-2024
The release of hazardous chemicals into aquatic environments has long been a known problem, but its full impact only recently realized. This study presents validated liquid chromatography–mass spectrometry (HPLC–MS/MS) method for detecting pharmaceutical and pesticide residues in mussels (Mytilus galloprovincialis). An innovative MS-compatible extraction was developed validated, demonstrating successful recovery rates analytes at three different concentration levels (25–95%). detected the...
A method of headspace solid phase microextraction using polydimethylsiloxane/divinylbenzene coating has been developed and applied for the determination some aromatic aldehydes in tea samples. The conditions derivatization benzaldehyde, 2,4-dimethylbenzaldehyde, 4-methoxybenzaldehyde, 2-furaldehyde with o-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine (PFBHA) aqueous solution have optimized. It is shown that amount analytes can be adsorpted at pH 4,0 increases 3–5 times compared to adsorption...
Background. One of the main advantages chromatography is ability to separate and simultaneously determine a large number compounds. In case analysis aldehydes, in addition optimization chromatographic separation detection, methods are designed include sample preparation derivatization with selection optimal conditions. Among available literature, there some that enable determination ranging from few 80 or more carbonyl compounds simultaneously, varying sensitivity. The aim this work was...
Idebenone (IDB) (2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone) is a compound synthesized in the early 1980s. Initially developed for treatment of cognitive disturbances and Alzheimer’s disease, IDB now studied Friedreich’s ataxia, Leber’s hereditary optic neuropathy (LHON), or Duchenne muscular dystrophy. The greatest disadvantage its low solubility water, resulting bioavailability. Galenic preparations customized doses are common pediatric patients, which can often prove to...