A5093772011- Attention Deficit Hyperactivity Disorder
- Genetics and Neurodevelopmental Disorders
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
MRC Cognition and Brain Sciences Unit
2025
University of Cambridge
2025
Executive function, an umbrella term used to describe the goal-directed regulation of thoughts, actions, and emotions, is important dimension implicated in neurodiversity established malleable predictor multiple adult outcomes. Neurodevelopmental differences have been linked both executive function strengths weaknesses, but evidence for associations between specific profiles neurodevelopmental conditions mixed. In this exploratory study, we adopt unsupervised machine learning approach...
Loss-of-function ZDHHC9 variants are associated with X-linked intellectual disability (XLID), rolandic epilepsy (RE) and developmental language difficulties. This study integrates human neurophysiological data a computational model to identify potential neural mechanism explaining ZDHHC9-associated differences in cortical function cognition. Magnetoencephalography (MEG) was collected during an auditory roving oddball paradigm from eight individuals loss-of-function variant (ZDHHC9 group)...
Loss-of-function ZDHHC9 variants are associated with X-linked intellectual disability (XLID), rolandic epilepsy (RE) and developmental language difficulties. This study integrates human neurophysiological data a computational model to identify potential neural mechanism explaining ZDHHC9-associated differences in cortical function cognition. Magnetoencephalography (MEG) was collected during an auditory roving oddball paradigm from eight individuals loss-of-function variant (ZDHHC9 group)...