A5016895169- Glaucoma and retinal disorders
- Workplace Health and Well-being
- Hippo pathway signaling and YAP/TAZ
- Proteoglycans and glycosaminoglycans research
- Pancreatic and Hepatic Oncology Research
- Retinal Development and Disorders
- Health, psychology, and well-being
- Musculoskeletal pain and rehabilitation
- TGF-β signaling in diseases
- Corneal Surgery and Treatments
- Protein Degradation and Inhibitors
- Agriculture and Farm Safety
- Cerebrospinal fluid and hydrocephalus
- Cultural Competency in Health Care
- Calpain Protease Function and Regulation
- Work-Family Balance Challenges
- Obesity, Physical Activity, Diet
- Medical and Biological Sciences
- Workplace Violence and Bullying
- Digital Imaging in Medicine
- S100 Proteins and Annexins
- Traumatic Brain Injury and Neurovascular Disturbances
- Axon Guidance and Neuronal Signaling
- Radiomics and Machine Learning in Medical Imaging
- Retinal and Macular Surgery
Manhattan Eye, Ear and Throat Hospital
2025
Northwell Health
2025
SUNY Upstate Medical University
2020-2024
Texas Tech University
2023-2024
Vanderbilt University Medical Center
2024
The University of Texas Health Science Center at San Antonio
2021-2023
The University of Texas Health Science Center at Houston
2023
Impairment of the trabecular meshwork (TM) is principal cause increased outflow resistance in glaucomatous eye. Yes-associated protein (YAP) and transcriptional coactivator with PDZ binding motif (TAZ) are emerging as potential mediators TM cell/tissue dysfunction. Furthermore, YAP/TAZ activity was recently found to be controlled by mevalonate pathway non-ocular cells. Clinically used statins block cascade were shown improve cell pathobiology; yet, link signaling not investigated. In this...
Purpose We sought to re-evaluate the utility of inpatient ocular Candidiasis screening, subsequent interventions, and outcomes, ultimately guide alignment between American Academy Ophthalmology (AAO) Infectious Diseases Society America (IDSA) guidelines.
BackgroundPerioperative vision loss following nonocular surgery is a rare but devastating complication. It typically occurs spinal, cardiac, or head and neck procedures with ischaemic optic neuropathy being the primary cause. Despite increased understanding of potential risk factors, such as prolonged prone positioning, anaemia hypotension, legal implications remain underexplored. This study investigates malpractice litigation outcomes related to perioperative in US.MethodsWe conducted...
Interactions between trabecular meshwork (TM) cells and their extracellular matrix (ECM) are critical for normal outflow function in the healthy eye. Multifactorial dysregulation of TM is principal cause elevated intraocular pressure that strongly associated with glaucomatous vision loss. Key characteristics diseased pathologic contraction actin stress fiber assembly, contributing to overall tissue stiffening. Among first-line glaucoma medications, Rho-associated kinase inhibitor (ROCKi)...
AbstractObjective Work-family conflict has been shown to adversely affect individuals’ health and function, particularly among individuals with chronic pain. The current study’s longitudinal serial mediation model examined whether work-to-family predicted greater pain interference through higher levels of family strain loneliness midlife adults pain.Methods measures study consisted 303 participants from two waves the national Midlife in United States (MIDUS) at wave II 2004 2006 (Mage = 57,...
Abstract Purpose Impairment of the trabecular meshwork (TM) is principal cause increased outflow resistance in glaucomatous eye. Yes-associated protein (YAP) and transcriptional coactivator with PDZ binding motif (TAZ) are emerging as potential mediators TM cell/tissue dysfunction. Furthermore, YAP/TAZ activity was recently found to be controlled by mevalonate pathway non-ocular cells. Clinically-used statins block cascade were shown improve cell pathobiology; yet, link signaling not...
Abstract As increasing numbers of MRIs and other scans are ordered for unrelated diseases, more people being diagnosed with cystic neoplasms the pancreas. While many or most these will likely remain benign, intraductal papillary mucinous (IPMNs) have a risk progression to cancer IPMN is now recognized as another precursor pancreatic ductal adenocarcinoma. We investigating mechanisms by which IPMNs progress from benign malignant disease in order identify markers targets block that...
Chronic pain is a prevalent condition with significant impacts on individuals' lives, including heightened stress and impaired physiological functioning. Given that work family are the two main social domains where manifests, this study aimed to investigate interactions between chronic pain, work-family stressors, diurnal cortisol patterns understand how affects daily life responses. We identified 1,413 adults matched controls within MIDUS II samples examine spillover, home levels across...
Introduction Melanotic schwannoma (MS) is a rare neoplasm composed of Schwann cells with melanosomes in various maturation stages. While MS typically observed spinal nerve roots or peripheral nerves, their involvement intraocular structures uncommon. Here, we present case spontaneous globe rupture as the presenting feature extension MS. Methods Enucleation was performed to remove lesion. Confirmatory light microscopy and immunohistochemistry were used properly diagnose differentiate from...
748 Background: Pancreatic cancer ranks 4th among cancers as a cause of death in the United States and 85- 90% pancreatic are ductal adenocarcinoma (PDAC). Previous studies have demonstrated 2 major types precursors to PDAC including intraepithelial neoplasia (PanIN) intraductal papillary mucinous (IPMN); mechanisms by which IPMNs give rise incompletely defined. We hypothesize that SMAD4 signaling is specifically involved IPMN pathway with PanINs having partially overlapping pathways...